 Sarcoma, Kaposi
"Sarcoma, Kaposi" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A multicentric, malignant neoplastic vascular proliferation characterized by the development of bluish-red cutaneous nodules, usually on the lower extremities, most often on the toes or feet, and slowly increasing in size and number and spreading to more proximal areas. The tumors have endothelium-lined channels and vascular spaces admixed with variably sized aggregates of spindle-shaped cells, and often remain confined to the skin and subcutaneous tissue, but widespread visceral involvement may occur. Kaposi's sarcoma occurs spontaneously in Jewish and Italian males in Europe and the United States. An aggressive variant in young children is endemic in some areas of Africa. A third form occurs in about 0.04% of kidney transplant patients. There is also a high incidence in AIDS patients. (From Dorland, 27th ed & Holland et al., Cancer Medicine, 3d ed, pp2105-7) HHV-8 is the suspected cause.
| Descriptor ID |
D012514
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| MeSH Number(s) |
C02.256.466.860 C04.557.450.795.850 C04.557.645.750
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| Concept/Terms |
Sarcoma, Kaposi- Sarcoma, Kaposi
- Kaposi's Sarcoma
- Kaposis Sarcoma
- Sarcoma, Kaposi's
- Multiple Idiopathic Pigmented Hemangiosarcoma
- Kaposi Sarcoma
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Below are MeSH descriptors whose meaning is more general than "Sarcoma, Kaposi".
Below are MeSH descriptors whose meaning is more specific than "Sarcoma, Kaposi".
This graph shows the total number of publications written about "Sarcoma, Kaposi" by people in this website by year, and whether "Sarcoma, Kaposi" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1988 | 1 | 0 | 1 | | 1989 | 0 | 1 | 1 | | 1990 | 0 | 1 | 1 | | 1996 | 1 | 1 | 2 | | 2002 | 1 | 0 | 1 | | 2005 | 1 | 1 | 2 | | 2009 | 1 | 0 | 1 | | 2010 | 2 | 0 | 2 | | 2016 | 0 | 1 | 1 |
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Below are the most recent publications written about "Sarcoma, Kaposi" by people in Profiles.
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Bolduc P, Roder N, Colgate E, Cheeseman SH. Care of Patients With HIV Infection: Medical Complications and Comorbidities. FP Essent. 2016 Apr; 443:16-22.
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Davis DA, Naiman NE, Wang V, Shrestha P, Haque M, Hu D, Anagho HA, Carey RF, Davidoff KS, Yarchoan R. Identification of Caspase Cleavage Sites in KSHV Latency-Associated Nuclear Antigen and Their Effects on Caspase-Related Host Defense Responses. PLoS Pathog. 2015 Jul; 11(7):e1005064.
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Lu CC, Li Z, Chu CY, Feng J, Feng J, Sun R, Rana TM. MicroRNAs encoded by Kaposi's sarcoma-associated herpesvirus regulate viral life cycle. EMBO Rep. 2010 Oct; 11(10):784-90.
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O'Donnell PJ, Pantanowitz L, Grayson W. Unique histologic variants of cutaneous Kaposi sarcoma. Am J Dermatopathol. 2010 May; 32(3):244-50.
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Strother RM, Gregory KM, Pastakia SD, Were P, Tenge C, Busakhala N, Jakait B, Schellhase EM, Rosmarin AG, Loehrer PJ. Retrospective analysis of the efficacy of gemcitabine for previously treated AIDS-associated Kaposi's sarcoma in western Kenya. Oncology. 2010; 78(1):5-11.
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Pantanowitz L, Otis CN, Dezube BJ. Immunohistochemistry in Kaposi's sarcoma. Clin Exp Dermatol. 2010 Jan; 35(1):68-72.
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Gill MB, Murphy JE, Fingeroth JD. Functional divergence of Kaposi's sarcoma-associated herpesvirus and related gamma-2 herpesvirus thymidine kinases: novel cytoplasmic phosphoproteins that alter cellular morphology and disrupt adhesion. J Virol. 2005 Dec; 79(23):14647-59.
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Zhang X, Wang JF, Chandran B, Persaud K, Pytowski B, Fingeroth J, Groopman JE. Kaposi's sarcoma-associated herpesvirus activation of vascular endothelial growth factor receptor 3 alters endothelial function and enhances infection. J Biol Chem. 2005 Jul 15; 280(28):26216-24.
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Dezube BJ, Zambela M, Sage DR, Wang JF, Fingeroth JD. Characterization of Kaposi sarcoma-associated herpesvirus/human herpesvirus-8 infection of human vascular endothelial cells: early events. Blood. 2002 Aug 1; 100(3):888-96.
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Li M, MacKey J, Czajak SC, Desrosiers RC, Lackner AA, Jung JU. Identification and characterization of Kaposi's sarcoma-associated herpesvirus K8.1 virion glycoprotein. J Virol. 1999 Feb; 73(2):1341-9.
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