Members of the tumor necrosis factor receptor superfamily with specificity for CD40 LIGAND. They are found on mature B-LYMPHOCYTES, some EPITHELIAL CELLS; and lymphoid DENDRITIC CELLS. Evidence suggests that CD40-dependent activation of B-cells is important for generation of memory B-cells within the germinal centers. Mutations in the CD40 antigen gene result in HYPER-IGM IMMUNODEFICIENCY SYNDROME, TYPE 3. Signaling of the receptor occurs through its association with TNF RECEPTOR-ASSOCIATED FACTORS.

Descriptor ID	D019013
MeSH Number(s)	D12.776.543.750.705.852.760.097 D23.050.301.264.051.140 D23.101.100.150.140
Concept/Terms	CD40 Antigens CD40 Antigens TNFRSF5 Receptor Receptor, TNFRSF5 CDw40 Antigen Antigen, CDw40 Tumor Necrosis Factor Receptor Superfamily, Member 5 CD40 Antigen Antigen, CD40 Antigens, CD40

Below are MeSH descriptors whose meaning is more general than "CD40 Antigens".

Below are MeSH descriptors whose meaning is related to "CD40 Antigens".

Below are MeSH descriptors whose meaning is more specific than "CD40 Antigens".