Genes, MHC Class II

"Genes, MHC Class II" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Genetic loci in the vertebrate major histocompatibility complex that encode polymorphic products which control the immune response to specific antigens. The genes are found in the HLA-D region in humans and includes H-2M, I-A, and I-E loci in mice.

Descriptor ID	D005802
MeSH Number(s)	G05.360.340.024.340.610.600 G05.360.340.024.380.500.600 G12.500.500.600
Concept/Terms	Genes, MHC Class II Genes, MHC Class II Genes, Class II MHC Class II Genes Class II Genes Class II Gene Gene, Class II Genes, HLA Class II

Below are MeSH descriptors whose meaning is more general than "Genes, MHC Class II".

Biological Sciences [G]
Genetic Phenomena [G05]
Genetic Structures [G05.360]
Genome [G05.360.340]
Genome Components [G05.360.340.024]
Genes [G05.360.340.024.340]
Major Histocompatibility Complex [G05.360.340.024.340.610]
Genes, MHC Class II [G05.360.340.024.340.610.600]
Genetic Loci [G05.360.340.024.380]
Major Histocompatibility Complex [G05.360.340.024.380.500]
Genes, MHC Class II [G05.360.340.024.380.500.600]
Immune System Phenomena [G12]
Immunogenetic Phenomena [G12.500]
Major Histocompatibility Complex [G12.500.500]
Genes, MHC Class II [G12.500.500.600]

Below are MeSH descriptors whose meaning is related to "Genes, MHC Class II".

Below are MeSH descriptors whose meaning is more specific than "Genes, MHC Class II".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Genes, MHC Class II" by people in this website by year, and whether "Genes, MHC Class II" was a major or minor topic of these publications.

Bar chart showing 17 publications over 14 distinct years, with a maximum of 3 publications in 2009

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1994	0	1	1
1995	0	1	1
1999	0	1	1
2004	1	0	1
2005	1	0	1
2006	0	2	2
2009	0	3	3
2010	1	0	1
2011	0	1	1
2012	0	1	1
2013	0	1	1
2014	0	1	1
2016	0	1	1
2018	0	1	1

Below are the most recent publications written about "Genes, MHC Class II" by people in Profiles.

Brehm MA, Kenney LL, Wiles MV, Low BE, Tisch RM, Burzenski L, Mueller C, Greiner DL, Shultz LD. Lack of acute xenogeneic graft- versus-host disease, but retention of T-cell function following engraftment of human peripheral blood mononuclear cells in NSG mice deficient in MHC class I and II expression. FASEB J. 2019 03; 33(3):3137-3151.

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Bradbury AM, Peterson TA, Gross AL, Wells SZ, McCurdy VJ, Wolfe KG, Dennis JC, Brunson BL, Gray-Edwards H, Randle AN, Johnson AK, Morrison EE, Cox NR, Baker HJ, Sena-Esteves M, Martin DR. AAV-mediated gene delivery attenuates neuroinflammation in feline Sandhoff disease. Neuroscience. 2017 01 06; 340:117-125.

View in: PubMed
McKinstry KK, Strutt TM, Bautista B, Zhang W, Kuang Y, Cooper AM, Swain SL. Effector CD4 T-cell transition to memory requires late cognate interactions that induce autocrine IL-2. Nat Commun. 2014 Nov 05; 5:5377.

View in: PubMed
Jakovcevski M, Bharadwaj R, Straubhaar J, Gao G, Gavin DP, Jakovcevski I, Mitchell AC, Akbarian S. Prefrontal cortical dysfunction after overexpression of histone deacetylase 1. Biol Psychiatry. 2013 Nov 01; 74(9):696-705.

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Riella LV, Liu T, Yang J, Chock S, Shimizu T, Mfarrej B, Batal I, Xiao X, Sayegh MH, Chandraker A. Deleterious effect of CTLA4-Ig on a Treg-dependent transplant model. Am J Transplant. 2012 Apr; 12(4):846-55.

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Covassin L, Laning J, Abdi R, Langevin DL, Phillips NE, Shultz LD, Brehm MA. Human peripheral blood CD4 T cell-engrafted non-obese diabetic-scid IL2r?(null) H2-Ab1 (tm1Gru) Tg (human leucocyte antigen D-related 4) mice: a mouse model of human allogeneic graft-versus-host disease. Clin Exp Immunol. 2011 Nov; 166(2):269-80.

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Pino S, Brehm MA, Covassin-Barberis L, King M, Gott B, Chase TH, Wagner J, Burzenski L, Foreman O, Greiner DL, Shultz LD. Development of novel major histocompatibility complex class I and class II-deficient NOD-SCID IL2R gamma chain knockout mice for modeling human xenogeneic graft-versus-host disease. Methods Mol Biol. 2010; 602:105-17.

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Yang J, Riella LV, Boenisch O, Popoola J, Robles S, Watanabe T, Vanguri V, Yuan X, Guleria I, Turka LA, Sayegh MH, Chandraker A. Paradoxical functions of B7: CD28 costimulation in a MHC class II-mismatched cardiac transplant model. Am J Transplant. 2009 Dec; 9(12):2837-44.

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Campbell JD, Buckland KF, McMillan SJ, Kearley J, Oldfield WL, Stern LJ, Gr?nlund H, van Hage M, Reynolds CJ, Boyton RJ, Cobbold SP, Kay AB, Altmann DM, Lloyd CM, Larch? M. Peptide immunotherapy in allergic asthma generates IL-10-dependent immunological tolerance associated with linked epitope suppression. J Exp Med. 2009 Jul 06; 206(7):1535-47.

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Stern LJ, Calvo-Calle JM. HLA-DR: molecular insights and vaccine design. Curr Pharm Des. 2009; 15(28):3249-61.

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