"Toll-Like Receptors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of pattern recognition receptors characterized by an extracellular leucine-rich domain and a cytoplasmic domain that share homology with the INTERLEUKIN 1 RECEPTOR and the DROSOPHILA toll protein. Following pathogen recognition, toll-like receptors recruit and activate a variety of SIGNAL TRANSDUCING ADAPTOR PROTEINS.
| Descriptor ID |
D051193
|
| MeSH Number(s) |
D12.776.543.750.705.910.500
|
| Concept/Terms |
Toll-Like Receptors- Toll-Like Receptors
- Toll Like Receptors
- Toll-Like Receptor
- Receptor, Toll-Like
- Toll Like Receptor
- Receptors, Toll-Like
- Receptors, Toll Like
|
Below are MeSH descriptors whose meaning is more general than "Toll-Like Receptors".
Below are MeSH descriptors whose meaning is more specific than "Toll-Like Receptors".
This graph shows the total number of publications written about "Toll-Like Receptors" by people in this website by year, and whether "Toll-Like Receptors" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 0 | 8 | 8 |
| 2000 | 0 | 7 | 7 |
| 2001 | 0 | 12 | 12 |
| 2002 | 0 | 13 | 13 |
| 2003 | 0 | 21 | 21 |
| 2004 | 0 | 43 | 43 |
| 2005 | 5 | 19 | 24 |
| 2006 | 11 | 3 | 14 |
| 2007 | 17 | 3 | 20 |
| 2008 | 9 | 5 | 14 |
| 2009 | 9 | 3 | 12 |
| 2010 | 5 | 4 | 9 |
| 2011 | 5 | 9 | 14 |
| 2012 | 1 | 3 | 4 |
| 2013 | 8 | 7 | 15 |
| 2014 | 5 | 2 | 7 |
| 2015 | 4 | 1 | 5 |
| 2016 | 5 | 3 | 8 |
| 2017 | 2 | 3 | 5 |
| 2018 | 2 | 1 | 3 |
| 2019 | 3 | 2 | 5 |
| 2020 | 3 | 2 | 5 |
To return to the timeline,
click here.
Below are the most recent publications written about "Toll-Like Receptors" by people in Profiles.
-
Sato R, Reuter T, Hiranuma R, Shibata T, Fukui R, Motoi Y, Murakami Y, Tsukamoto H, Yamazaki S, Liu K, Saitoh SI, Latz E, Miyake K. The impact of cell maturation and tissue microenvironments on the expression of endosomal Toll-like receptors in monocytes and macrophages. Int Immunol. 2020 11 23; 32(12):785-798.
-
Pereira LMN, Assis PA, de Ara?jo NM, Durso DF, Junqueira C, Ata?de MA, Pereira DB, Lien E, Fitzgerald KA, Zamboni DS, Golenbock DT, Gazzinelli RT. Caspase-8 mediates inflammation and disease in rodent malaria. Nat Commun. 2020 09 14; 11(1):4596.
-
Koupenova M, Freedman JE. Platelets and Immunity: Going Viral. Arterioscler Thromb Vasc Biol. 2020 07; 40(7):1605-1607.
-
Marshak-Rothstein A, Manning CA, Baum R, Pawaria S, Gravallese EM. Interplay of Cyclic GMP-AMP Synthase/Stimulator of IFN Genes and Toll-Like Receptor Nucleic Acid Sensing Pathways in Autoinflammation and Abnormal Bone Formation due to DNaseII-Deficiency. Viral Immunol. 2020 04; 33(3):246-249.
-
Fitzgerald KA, Kagan JC. Toll-like Receptors and the Control of Immunity. Cell. 2020 03 19; 180(6):1044-1066.
-
Shahini N, Schjalm C, Nilsson PH, Holt MF, ?gaard JDS, Lien E, Ahmed MS, Attramadal H, Aukrust P, Yndestad A, Mollnes TE, Louwe MC. Complement component C3 and the TLR co-receptor CD14 are not involved in angiotensin II induced cardiac remodelling. Biochem Biophys Res Commun. 2020 03 19; 523(4):867-873.
-
Antonelli LR, Junqueira C, Vinetz JM, Golenbock DT, Ferreira MU, Gazzinelli RT. The immunology of Plasmodium vivax malaria. Immunol Rev. 2020 01; 293(1):163-189.
-
Lee MH, Gallo PM, Hooper KM, Corradetti C, Ganea D, Caricchio R, Gallucci S. The cytokine network type I IFN-IL-27-IL-10 is augmented in murine and human lupus. J Leukoc Biol. 2019 10; 106(4):967-975.
-
Chowdhury M, Li CF, He Z, Lu Y, Liu XS, Wang YF, Ip YT, Strand MR, Yu XQ. Toll family members bind multiple Sp?tzle proteins and activate antimicrobial peptide gene expression in Drosophila. J Biol Chem. 2019 06 28; 294(26):10172-10181.
-
West C, Rus F, Chen Y, Kleino A, Gangloff M, Gammon DB, Silverman N. IIV-6 Inhibits NF-?B Responses in Drosophila. Viruses. 2019 05 01; 11(5).