 Serotonin
"Serotonin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A biochemical messenger and regulator, synthesized from the essential amino acid L-TRYPTOPHAN. In humans it is found primarily in the central nervous system, gastrointestinal tract, and blood platelets. Serotonin mediates several important physiological functions including neurotransmission, gastrointestinal motility, hemostasis, and cardiovascular integrity. Multiple receptor families (RECEPTORS, SEROTONIN) explain the broad physiological actions and distribution of this biochemical mediator.
| Descriptor ID |
D012701
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| MeSH Number(s) |
D02.092.211.215.801.852 D03.438.473.914.814 D23.469.050.650
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| Concept/Terms |
Serotonin- Serotonin
- 5-HT
- Enteramine
- Hippophaine
- 3-(2-Aminoethyl)-1H-indol-5-ol
- 5-Hydroxytryptamine
- 5 Hydroxytryptamine
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Below are MeSH descriptors whose meaning is more general than "Serotonin".
Below are MeSH descriptors whose meaning is more specific than "Serotonin".
This graph shows the total number of publications written about "Serotonin" by people in this website by year, and whether "Serotonin" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1982 | 1 | 0 | 1 | | 1984 | 1 | 0 | 1 | | 1985 | 0 | 1 | 1 | | 1992 | 1 | 0 | 1 | | 1993 | 1 | 0 | 1 | | 1994 | 2 | 0 | 2 | | 1995 | 0 | 1 | 1 | | 1996 | 0 | 1 | 1 | | 1997 | 0 | 1 | 1 | | 1998 | 1 | 0 | 1 | | 1999 | 0 | 1 | 1 | | 2001 | 0 | 1 | 1 | | 2002 | 2 | 3 | 5 | | 2003 | 2 | 1 | 3 | | 2004 | 2 | 0 | 2 | | 2005 | 0 | 4 | 4 | | 2006 | 4 | 1 | 5 | | 2007 | 3 | 3 | 6 | | 2008 | 0 | 1 | 1 | | 2009 | 2 | 1 | 3 | | 2010 | 0 | 1 | 1 | | 2011 | 0 | 1 | 1 | | 2012 | 1 | 1 | 2 | | 2013 | 2 | 0 | 2 | | 2015 | 0 | 1 | 1 | | 2016 | 1 | 0 | 1 | | 2017 | 2 | 0 | 2 |
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Below are the most recent publications written about "Serotonin" by people in Profiles.
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Haynes RL, Frelinger AL, Giles EK, Goldstein RD, Tran H, Kozakewich HP, Haas EA, Gerrits AJ, Mena OJ, Trachtenberg FL, Paterson DS, Berry GT, Adeli K, Kinney HC, Michelson AD. High serum serotonin in sudden infant death syndrome. Proc Natl Acad Sci U S A. 2017 07 18; 114(29):7695-7700.
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Lavoie B, Lian JB, Mawe GM. Regulation of Bone Metabolism by Serotonin. Adv Exp Med Biol. 2017; 1033:35-46.
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Lu H, Yu J, Wang J, Wu L, Xiao H, Gao R. Simultaneous quantification of neuroactive dopamine serotonin and kynurenine pathway metabolites in gender-specific youth urine by ultra performance liquid chromatography tandem high resolution mass spectrometry. J Pharm Biomed Anal. 2016 Apr 15; 122:42-51.
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Wu S, Bellve KD, Fogarty KE, Melikian HE. Ack1 is a dopamine transporter endocytic brake that rescues a trafficking-dysregulated ADHD coding variant. Proc Natl Acad Sci U S A. 2015 Dec 15; 112(50):15480-5.
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Blair LM, Colby Davie EA, Sperry J. Total synthesis of putative montamine and a proposed structural reassignment. Org Biomol Chem. 2014 Sep 21; 12(35):6878-84.
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Engster KM, Frommelt L, Hofmann T, Nolte S, Fischer F, Rose M, Stengel A, Kobelt P. Peripheral injected cholecystokinin-8S modulates the concentration of serotonin in nerve fibers of the rat brainstem. Peptides. 2014 Sep; 59:25-33.
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Li HJ, Johnston B, Aiello D, Caffrey DR, Giel-Moloney M, Rindi G, Leiter AB. Distinct cellular origins for serotonin-expressing and enterochromaffin-like cells in the gastric corpus. Gastroenterology. 2014 Mar; 146(3):754-764.e3.
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Harrington RA, Lee LC, Crum RM, Zimmerman AW, Hertz-Picciotto I. Serotonin hypothesis of autism: implications for selective serotonin reuptake inhibitor use during pregnancy. Autism Res. 2013 Jun; 6(3):149-68.
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Biezonski DK, Piper BJ, Shinday NM, Kim PJ, Ali SF, Meyer JS. Effects of a short-course MDMA binge on dopamine transporter binding and on levels of dopamine and its metabolites in adult male rats. Eur J Pharmacol. 2013 Feb 15; 701(1-3):176-80.
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Sumara G, Sumara O, Kim JK, Karsenty G. Gut-derived serotonin is a multifunctional determinant to fasting adaptation. Cell Metab. 2012 Nov 7; 16(5):588-600.
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