Cyclodextrins

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"Cyclodextrins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A homologous group of cyclic GLUCANS consisting of alpha-1,4 bound glucose units obtained by the action of cyclodextrin glucanotransferase on starch or similar substrates. The enzyme is produced by certain species of Bacillus. Cyclodextrins form inclusion complexes with a wide variety of substances.

Descriptor ID	D003505
MeSH Number(s)	D04.345.103 D09.301.915.400.375 D09.698.365.855.400.375
Concept/Terms	Cyclodextrins Cyclodextrins Cyclomaltooligosaccharides Cyclodextrin Derivatives Derivatives, Cyclodextrin Cycloamylose

Below are MeSH descriptors whose meaning is more general than "Cyclodextrins".

Chemicals and Drugs [D]
Polycyclic Compounds [D04]
Macrocyclic Compounds [D04.345]
Cyclodextrins [D04.345.103]
Carbohydrates [D09]
Dietary Carbohydrates [D09.301]
Starch [D09.301.915]
Dextrins [D09.301.915.400]
Cyclodextrins [D09.301.915.400.375]
Polysaccharides [D09.698]
Glucans [D09.698.365]
Starch [D09.698.365.855]
Dextrins [D09.698.365.855.400]
Cyclodextrins [D09.698.365.855.400.375]

Below are MeSH descriptors whose meaning is related to "Cyclodextrins".

Below are MeSH descriptors whose meaning is more specific than "Cyclodextrins".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Cyclodextrins" by people in this website by year, and whether "Cyclodextrins" was a major or minor topic of these publications.

Bar chart showing 13 publications over 10 distinct years, with a maximum of 2 publications in 1999 and 2019 and 2022

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1999	1	1	2
2000	0	1	1
2002	1	0	1
2003	0	1	1
2013	1	0	1
2017	1	0	1
2018	1	0	1
2019	1	1	2
2021	1	0	1
2022	2	0	2

Below are the most recent publications written about "Cyclodextrins" by people in Profiles.

Hu Y, Guo C, Lin Q, Hu J, Li X, Sang S, McClements DJ, Long J, Jin Z, Wang J, Qiu C. Complexation of curcumin with cyclodextrins adjusts its binding to plasma proteins. Food Funct. 2022 Aug 30; 13(17):8920-8929.

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Liu Y, Qiu C, Li X, McClements DJ, Wang C, Zhang Z, Jiao A, Long J, Zhu K, Wang J, Jin Z. Application of starch-based nanoparticles and cyclodextrin for prebiotics delivery and controlled glucose release in the human gut: a review. Crit Rev Food Sci Nutr. 2023; 63(23):6126-6137.

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Hu Y, Qiu C, McClements DJ, Qin Y, Fan L, Xu X, Wang J, Jin Z. Simple Strategy Preparing Cyclodextrin Carboxylate as a Highly Effective Carrier for Bioactive Compounds. J Agric Food Chem. 2021 Sep 22; 69(37):11006-11014.

View in: PubMed
Vu TP, He L, McClements DJ, Decker EA. Effects of water activity, sugars, and proteins on lipid oxidative stability of low moisture model crackers. Food Res Int. 2020 04; 130:108844.

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Qiu C, McClements DJ, Jin Z, Wang C, Qin Y, Xu X, Wang J. Development of nanoscale bioactive delivery systems using sonication: Glycyrrhizic acid-loaded cyclodextrin metal-organic frameworks. J Colloid Interface Sci. 2019 Oct 01; 553:549-556.

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Guimaraes PPG, Tan M, Tammela T, Wu K, Chung A, Oberli M, Wang K, Spektor R, Riley RS, Viana CTR, Jacks T, Langer R, Mitchell MJ. Potent in vivo lung cancer Wnt signaling inhibition via cyclodextrin-LGK974 inclusion complexes. J Control Release. 2018 11 28; 290:75-87.

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Bakke SS, Aune MH, Niyonzima N, Pilely K, Ryan L, Skjelland M, Garred P, Aukrust P, Halvorsen B, Latz E, Dam?s JK, Mollnes TE, Espevik T. Cyclodextrin Reduces Cholesterol Crystal-Induced Inflammation by Modulating Complement Activation. J Immunol. 2017 10 15; 199(8):2910-2920.

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Hari P, Aljitawi OS, Arce-Lara C, Nath R, Callander N, Bhat G, Allen LF, Stockerl-Goldstein K. A Phase IIb, Multicenter, Open-Label, Safety, and Efficacy Study of High-Dose, Propylene Glycol-Free Melphalan Hydrochloride for Injection (EVOMELA) for Myeloablative Conditioning in Multiple Myeloma Patients Undergoing Autologous Transplantation. Biol Blood Marrow Transplant. 2015 Dec; 21(12):2100-2105.

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Weiss GJ, Chao J, Neidhart JD, Ramanathan RK, Bassett D, Neidhart JA, Choi CHJ, Chow W, Chung V, Forman SJ, Garmey E, Hwang J, Kalinoski DL, Koczywas M, Longmate J, Melton RJ, Morgan R, Oliver J, Peterkin JJ, Ryan JL, Schluep T, Synold TW, Twardowski P, Davis ME, Yen Y. First-in-human phase 1/2a trial of CRLX101, a cyclodextrin-containing polymer-camptothecin nanopharmaceutical in patients with advanced solid tumor malignancies. Invest New Drugs. 2013 Aug; 31(4):986-1000.

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Burkart A, Samii B, Corvera S, Shpetner HS. Regulation of the SHP-2 tyrosine phosphatase by a novel cholesterol- and cell confluence-dependent mechanism. J Biol Chem. 2003 May 16; 278(20):18360-7.

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