Mitogen-Activated Protein Kinase 1
"Mitogen-Activated Protein Kinase 1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A proline-directed serine/threonine protein kinase which mediates signal transduction from the cell surface to the nucleus. Activation of the enzyme by phosphorylation leads to its translocation into the nucleus where it acts upon specific transcription factors. p40 MAPK and p41 MAPK are isoforms.
| Descriptor ID |
D019950
|
| MeSH Number(s) |
D08.811.913.696.620.682.700.567.249.500 D12.644.360.450.169.500 D12.776.476.450.169.500
|
| Concept/Terms |
Mitogen-Activated Protein Kinase 1- Mitogen-Activated Protein Kinase 1
- Mitogen Activated Protein Kinase 1
- p42 MAPK
- p42(Mitogen-Activated Protein Kinase)
- p42(Mapk) Kinase
- p42 MAP Kinase
- MAP Kinase, p42
- MAPK2 Mitogen-Activated Protein Kinase
- MAPK2 Mitogen Activated Protein Kinase
- Extracellular Signal-Regulated Kinase 2
- Extracellular Signal Regulated Kinase 2
- Mitogen-Activated Protein Kinase 2
- Mitogen Activated Protein Kinase 2
- MAPK1 Mitogen-Activated Protein Kinase
- MAPK1 Mitogen Activated Protein Kinase
- p42(Mapk)
- MAP Kinase 2
|
Below are MeSH descriptors whose meaning is more general than "Mitogen-Activated Protein Kinase 1".
Below are MeSH descriptors whose meaning is more specific than "Mitogen-Activated Protein Kinase 1".
This graph shows the total number of publications written about "Mitogen-Activated Protein Kinase 1" by people in this website by year, and whether "Mitogen-Activated Protein Kinase 1" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2007 | 0 | 1 | 1 |
| 2015 | 0 | 1 | 1 |
| 2017 | 0 | 1 | 1 |
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Below are the most recent publications written about "Mitogen-Activated Protein Kinase 1" by people in Profiles.
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Thamilselvan V, Menon M, Stein GS, Valeriote F, Thamilselvan S. Combination of Carmustine and Selenite Inhibits EGFR Mediated Growth Signaling in Androgen-Independent Prostate Cancer Cells. J Cell Biochem. 2017 12; 118(12):4331-4340.
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Acharya D, Hainer SJ, Yoon Y, Wang F, Bach I, Rivera-P?rez JA, Fazzio TG. KAT-Independent Gene Regulation by Tip60 Promotes ESC Self-Renewal but Not Pluripotency. Cell Rep. 2017 04 25; 19(4):671-679.
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Myklebust JH, Brody J, Kohrt HE, Kolstad A, Czerwinski DK, W?lchli S, Green MR, Tr?en G, Liest?l K, Beiske K, Houot R, Delabie J, Alizadeh AA, Irish JM, Levy R. Distinct patterns of B-cell receptor signaling in non-Hodgkin lymphomas identified by single-cell profiling. Blood. 2017 02 09; 129(6):759-770.
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Spinazzola JM, Smith TC, Liu M, Luna EJ, Barton ER. Gamma-sarcoglycan is required for the response of archvillin to mechanical stimulation in skeletal muscle. Hum Mol Genet. 2015 May 01; 24(9):2470-81.
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Khurana L, Ali HI, Olszewska T, Ahn KH, Damaraju A, Kendall DA, Lu D. Optimization of chemical functionalities of indole-2-carboxamides to improve allosteric parameters for the cannabinoid receptor 1 (CB1). J Med Chem. 2014 Apr 10; 57(7):3040-52.
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Shan Z, Cuadra AE, Sumners C, Raizada MK. Characterization of a functional (pro)renin receptor in rat brain neurons. Exp Physiol. 2008 May; 93(5):701-8.
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Fitzgerald JB, Jin M, Chai DH, Siparsky P, Fanning P, Grodzinsky AJ. Shear- and compression-induced chondrocyte transcription requires MAPK activation in cartilage explants. J Biol Chem. 2008 Mar 14; 283(11):6735-43.
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Merdek KD, Yang X, Taglienti CA, Shaw LM, Mercurio AM. Intrinsic signaling functions of the beta4 integrin intracellular domain. J Biol Chem. 2007 Oct 12; 282(41):30322-30.
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Chakravarti A, Chakladar A, Delaney MA, Latham DE, Loeffler JS. The epidermal growth factor receptor pathway mediates resistance to sequential administration of radiation and chemotherapy in primary human glioblastoma cells in a RAS-dependent manner. Cancer Res. 2002 Aug 01; 62(15):4307-15.
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Song S, Freedman J, Mody M, Lazarus AH. Porcine von Willebrand factor and thrombin induce the activation of c-Jun amino-terminal kinase (JNK/SAPK) whereas only thrombin induces activation of extracellular signal-related kinase 2 (ERK2) in human platelets. Br J Haematol. 2000 Jun; 109(4):851-6.