Sterol Regulatory Element Binding Protein 1

"Sterol Regulatory Element Binding Protein 1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A sterol regulatory element binding protein that regulates expression of GENES involved in FATTY ACIDS metabolism and LIPOGENESIS. Two major isoforms of the protein exist due to ALTERNATIVE SPLICING.

Descriptor ID	D051780
MeSH Number(s)	D12.776.260.103.500.750.500 D12.776.260.108.092.750.500 D12.776.930.125.500.750.500 D12.776.930.127.092.750.500
Concept/Terms	Sterol Regulatory Element Binding Protein 1 Sterol Regulatory Element Binding Protein 1 SREBP1 Protein Sterol Regulatory Element-Binding Protein 1 SRE-1 Binding Protein SRE 1 Binding Protein Sterol Regulatory Element Binding Protein 1c Sterol Regulatory Element Binding Protein 1c SREBP-1c SREBP 1c Transcription Factor ADD1 ADD1, Transcription Factor Adipocyte Determination And Differentiation Factor 1 Sterol Regulatory Element Binding Protein 1a Sterol Regulatory Element Binding Protein 1a SREBP-1a SREBP 1a

Below are MeSH descriptors whose meaning is more general than "Sterol Regulatory Element Binding Protein 1".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
DNA-Binding Proteins [D12.776.260]
Basic Helix-Loop-Helix Transcription Factors [D12.776.260.103]
Basic Helix-Loop-Helix Leucine Zipper Transcription Factors [D12.776.260.103.500]
Sterol Regulatory Element Binding Proteins [D12.776.260.103.500.750]
Sterol Regulatory Element Binding Protein 1 [D12.776.260.103.500.750.500]
Basic-Leucine Zipper Transcription Factors [D12.776.260.108]
Basic Helix-Loop-Helix Leucine Zipper Transcription Factors [D12.776.260.108.092]
Sterol Regulatory Element Binding Proteins [D12.776.260.108.092.750]
Sterol Regulatory Element Binding Protein 1 [D12.776.260.108.092.750.500]
Transcription Factors [D12.776.930]
Basic Helix-Loop-Helix Transcription Factors [D12.776.930.125]
Basic Helix-Loop-Helix Leucine Zipper Transcription Factors [D12.776.930.125.500]
Sterol Regulatory Element Binding Proteins [D12.776.930.125.500.750]
Sterol Regulatory Element Binding Protein 1 [D12.776.930.125.500.750.500]
Basic-Leucine Zipper Transcription Factors [D12.776.930.127]
Basic Helix-Loop-Helix Leucine Zipper Transcription Factors [D12.776.930.127.092]
Sterol Regulatory Element Binding Proteins [D12.776.930.127.092.750]
Sterol Regulatory Element Binding Protein 1 [D12.776.930.127.092.750.500]

Below are MeSH descriptors whose meaning is related to "Sterol Regulatory Element Binding Protein 1".

Below are MeSH descriptors whose meaning is more specific than "Sterol Regulatory Element Binding Protein 1".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Sterol Regulatory Element Binding Protein 1" by people in this website by year, and whether "Sterol Regulatory Element Binding Protein 1" was a major or minor topic of these publications.

Bar chart showing 5 publications over 4 distinct years, with a maximum of 2 publications in 2011

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2010	1	0	1
2011	1	1	2
2012	0	1	1
2014	0	1	1

Below are the most recent publications written about "Sterol Regulatory Element Binding Protein 1" by people in Profiles.

Smulan LJ, Ding W, Freinkman E, Gujja S, Edwards YJK, Walker AK. Cholesterol-Independent SREBP-1 Maturation Is Linked to ARF1 Inactivation. Cell Rep. 2016 06 28; 16(1):9-18.

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Ambade A, Catalano D, Lim A, Kopoyan A, Shaffer SA, Mandrekar P. Inhibition of heat shock protein 90 alleviates steatosis and macrophage activation in murine alcoholic liver injury. J Hepatol. 2014 Oct; 61(4):903-11.

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Liew CW, Assmann A, Templin AT, Raum JC, Lipson KL, Rajan S, Qiang G, Hu J, Kawamori D, Lindberg I, Philipson LH, Sonenberg N, Goldfine AB, Stoffers DA, Mirmira RG, Urano F, Kulkarni RN. Insulin regulates carboxypeptidase E by modulating translation initiation scaffolding protein eIF4G1 in pancreatic ? cells. Proc Natl Acad Sci U S A. 2014 Jun 03; 111(22):E2319-28.

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Danai LV, Guilherme A, Guntur KV, Straubhaar J, Nicoloro SM, Czech MP. Map4k4 suppresses Srebp-1 and adipocyte lipogenesis independent of JNK signaling. J Lipid Res. 2013 Oct; 54(10):2697-707.

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Johnston-Cox H, Koupenova M, Yang D, Corkey B, Gokce N, Farb MG, LeBrasseur N, Ravid K. The A2b adenosine receptor modulates glucose homeostasis and obesity. PLoS One. 2012; 7(7):e40584.

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Koupenova M, Johnston-Cox H, Vezeridis A, Gavras H, Yang D, Zannis V, Ravid K. A2b adenosine receptor regulates hyperlipidemia and atherosclerosis. Circulation. 2012 Jan 17; 125(2):354-63.

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Walker AK, Jacobs RL, Watts JL, Rottiers V, Jiang K, Finnegan DM, Shioda T, Hansen M, Yang F, Niebergall LJ, Vance DE, Tzoneva M, Hart AC, N??r AM. A conserved SREBP-1/phosphatidylcholine feedback circuit regulates lipogenesis in metazoans. Cell. 2011 Nov 11; 147(4):840-52.

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Walker AK, Yang F, Jiang K, Ji JY, Watts JL, Purushotham A, Boss O, Hirsch ML, Ribich S, Smith JJ, Israelian K, Westphal CH, Rodgers JT, Shioda T, Elson SL, Mulligan P, Najafi-Shoushtari H, Black JC, Thakur JK, Kadyk LC, Whetstine JR, Mostoslavsky R, Puigserver P, Li X, Dyson NJ, Hart AC, N??r AM. Conserved role of SIRT1 orthologs in fasting-dependent inhibition of the lipid/cholesterol regulator SREBP. Genes Dev. 2010 Jul 01; 24(13):1403-17.

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Krause JC, Toye MP, Stechenberg BW, Reiter EO, Allen HF. HIV--associated lipodystrophy in children. Pediatr Endocrinol Rev. 2005 Sep; 3(1):45-51.

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