Nucleotidyltransferases

"Nucleotidyltransferases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A class of enzymes that transfers nucleotidyl residues. EC 2.7.7.

Descriptor ID	D009713
MeSH Number(s)	D08.811.913.696.445
Concept/Terms	Nucleotidyltransferases Nucleotidyltransferases

Below are MeSH descriptors whose meaning is more general than "Nucleotidyltransferases".

Chemicals and Drugs [D]
Enzymes and Coenzymes [D08]
Enzymes [D08.811]
Transferases [D08.811.913]
Phosphotransferases [D08.811.913.696]
Nucleotidyltransferases [D08.811.913.696.445]

Below are MeSH descriptors whose meaning is related to "Nucleotidyltransferases".

Below are MeSH descriptors whose meaning is more specific than "Nucleotidyltransferases".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Nucleotidyltransferases" by people in this website by year, and whether "Nucleotidyltransferases" was a major or minor topic of these publications.

Bar chart showing 28 publications over 13 distinct years, with a maximum of 6 publications in 2017

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2003	1	0	1
2005	1	0	1
2008	0	1	1
2013	0	1	1
2014	1	1	2
2015	2	0	2
2016	3	0	3
2017	5	1	6
2018	0	1	1
2019	1	0	1
2020	0	1	1
2021	3	0	3
2023	1	4	5

Below are the most recent publications written about "Nucleotidyltransferases" by people in Profiles.

Barasa L, Chaudhuri S, Zhou JY, Jiang Z, Choudhary S, Green RM, Wiggin E, Cameron M, Humphries F, Fitzgerald KA, Thompson PR. Development of LB244, an Irreversible STING Antagonist. J Am Chem Soc. 2023 09 20; 145(37):20273-20288.

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Humphries F, Shmuel-Galia L, Jiang Z, Zhou JY, Barasa L, Mondal S, Wilson R, Sultana N, Shaffer SA, Ng SL, Pesiridis GS, Thompson PR, Fitzgerald KA. Targeting STING oligomerization with small-molecule inhibitors. Proc Natl Acad Sci U S A. 2023 08 15; 120(33):e2305420120.

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Broekema N, Mertens ME, Angelova M, Orzalli MH, Oh HS, Knipe DM. Herpes simplex virus infected cell protein 8 is required for viral inhibition of the cGAS pathway. Virology. 2023 08; 585:34-41.

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de Carvalho Ribeiro M, Cho Y, Mehta J, Wang X, Babuta M, Copeland C, Hussein H, Catalano D, Wang Y, Szabo G. Protective role of cGAS in NASH is related to the maintenance of intestinal homeostasis. Liver Int. 2023 09; 43(9):1937-1949.

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Gao KM, Marshak-Rothstein A, Fitzgerald KA. Type-1 interferon-dependent and -independent mechanisms in cyclic GMP-AMP synthase-stimulator of interferon genes-driven auto-inflammation. Curr Opin Immunol. 2023 02; 80:102280.

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Leone P, Tolomeo M, Piancone E, Puzzovio PG, De Giorgi C, Indiveri C, Di Schiavi E, Barile M. Mimicking human riboflavin responsive neuromuscular disorders by silencing flad-1 gene in C. elegans: Alteration of vitamin transport and cholinergic transmission. IUBMB Life. 2022 07; 74(7):672-683.

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West C, Silverman N. cGAS-like receptors put a sting into the evolution of immune defence. Nature. 2021 09; 597(7874):34-35.

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Motwani M, McGowan J, Antonovitch J, Gao KM, Jiang Z, Sharma S, Baltus GA, Nickerson KM, Marshak-Rothstein A, Fitzgerald KA. cGAS-STING Pathway Does Not Promote Autoimmunity in Murine Models of SLE. Front Immunol. 2021; 12:605930.

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Humphries F, Fitzgerald KA. Loosening the grip on nuclear cGAS. Nat Genet. 2020 12; 52(12):1269-1270.

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Motwani M, Pesiridis S, Fitzgerald KA. DNA sensing by the cGAS-STING pathway in health and disease. Nat Rev Genet. 2019 11; 20(11):657-674.

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