Receptors, Metabotropic Glutamate

"Receptors, Metabotropic Glutamate" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Cell surface proteins that bind glutamate and act through G-proteins to influence second messenger systems. Several types of metabotropic glutamate receptors have been cloned. They differ in pharmacology, distribution, and mechanisms of action.

Descriptor ID	D018094
MeSH Number(s)	D12.776.543.750.695.450 D12.776.543.750.720.200.450.500
Concept/Terms	Receptors, Metabotropic Glutamate Receptors, Metabotropic Glutamate Metabotropic Glutamate Receptor Glutamate Receptor, Metabotropic Receptor, Metabotropic Glutamate Metabotropic Glutamate Receptors Receptors, Glutamate, Metabotropic Glutamate Receptors, Metabotropic

Below are MeSH descriptors whose meaning is more general than "Receptors, Metabotropic Glutamate".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Membrane Proteins [D12.776.543]
Receptors, Cell Surface [D12.776.543.750]
Receptors, G-Protein-Coupled [D12.776.543.750.695]
Receptors, Metabotropic Glutamate [D12.776.543.750.695.450]
Receptors, Neurotransmitter [D12.776.543.750.720]
Receptors, Amino Acid [D12.776.543.750.720.200]
Receptors, Glutamate [D12.776.543.750.720.200.450]
Receptors, Metabotropic Glutamate [D12.776.543.750.720.200.450.500]

Below are MeSH descriptors whose meaning is related to "Receptors, Metabotropic Glutamate".

Below are MeSH descriptors whose meaning is more specific than "Receptors, Metabotropic Glutamate".

Receptors, Metabotropic Glutamate
Receptor, Metabotropic Glutamate 5

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Receptors, Metabotropic Glutamate" by people in this website by year, and whether "Receptors, Metabotropic Glutamate" was a major or minor topic of these publications.

Bar chart showing 28 publications over 17 distinct years, with a maximum of 3 publications in 1996 and 2008 and 2010 and 2011

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1995	2	0	2
1996	3	0	3
2002	0	1	1
2005	1	0	1
2006	1	0	1
2007	1	0	1
2008	1	2	3
2010	1	2	3
2011	2	1	3
2012	1	1	2
2015	1	0	1
2018	1	0	1
2019	1	0	1
2020	0	2	2
2021	1	0	1
2023	1	0	1
2024	1	0	1

Below are the most recent publications written about "Receptors, Metabotropic Glutamate" by people in Profiles.

Nabit BP, Taylor A, Winder DG. Thalamocortical mGlu8 Modulates Dorsal Thalamus Excitatory Transmission and Sensorimotor Activity. J Neurosci. 2024 Jul 31; 44(31).

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Protasova MS, Andreeva TV, Klyushnikov SA, Illarioshkin SN, Rogaev EI. Genetic Variant in GRM1 Underlies Congenital Cerebellar Ataxia with No Obvious Intellectual Disability. Int J Mol Sci. 2023 Jan 12; 24(2).

View in: PubMed
Joffe ME, Winder DG, Conn PJ. Increased Synaptic Strength and mGlu2/3 Receptor Plasticity on Mouse Prefrontal Cortex Intratelencephalic Pyramidal Cells Following Intermittent Access to Ethanol. Alcohol Clin Exp Res. 2021 03; 45(3):518-529.

View in: PubMed
Yemini E, Lin A, Nejatbakhsh A, Varol E, Sun R, Mena GE, Samuel ADT, Paninski L, Venkatachalam V, Hobert O. NeuroPAL: A Multicolor Atlas for Whole-Brain Neuronal Identification in C.?elegans. Cell. 2021 01 07; 184(1):272-288.e11.

View in: PubMed
Hien A, Molinaro G, Liu B, Huber KM, Richter JD. Ribosome profiling in mouse hippocampus: plasticity-induced regulation and bidirectional control by TSC2 and FMRP. Mol Autism. 2020 10 14; 11(1):78.

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Joffe ME, Santiago CI, Oliver KH, Maksymetz J, Harris NA, Engers JL, Lindsley CW, Winder DG, Conn PJ. mGlu2 and mGlu3 Negative Allosteric Modulators Divergently Enhance Thalamocortical Transmission and Exert Rapid Antidepressant-like Effects. Neuron. 2020 01 08; 105(1):46-59.e3.

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Joffe ME, Centanni SW, Jaramillo AA, Winder DG, Conn PJ. Metabotropic Glutamate Receptors in Alcohol Use Disorder: Physiology, Plasticity, and Promising Pharmacotherapies. ACS Chem Neurosci. 2018 09 19; 9(9):2188-2204.

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Jin LE, Wang M, Galvin VC, Lightbourne TC, Conn PJ, Arnsten AFT, Paspalas CD. mGluR2 versus mGluR3 Metabotropic Glutamate Receptors in Primate Dorsolateral Prefrontal Cortex: Postsynaptic mGluR3 Strengthen Working Memory Networks. Cereb Cortex. 2018 03 01; 28(3):974-987.

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Wills TA, Baucum AJ, Holleran KM, Chen Y, Pasek JG, Delpire E, Tabb DL, Colbran RJ, Winder DG. Chronic intermittent alcohol disrupts the GluN2B-associated proteome and specifically regulates group I mGlu receptor-dependent long-term depression. Addict Biol. 2017 Mar; 22(2):275-290.

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Gabriel L, Lvov A, Orthodoxou D, Rittenhouse AR, Kobertz WR, Melikian HE. The acid-sensitive, anesthetic-activated potassium leak channel, KCNK3, is regulated by 14-3-3?-dependent, protein kinase C (PKC)-mediated endocytic trafficking. J Biol Chem. 2012 Sep 21; 287(39):32354-66.

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