Mitogen-Activated Protein Kinase 14
"Mitogen-Activated Protein Kinase 14" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A 38-kDa mitogen-activated protein kinase that is abundantly expressed in a broad variety of cell types. It is involved in the regulation of cellular stress responses as well as the control of proliferation and survival of many cell types. The kinase activity of the enzyme is inhibited by the pyridinyl-imidazole compound SB 203580.
| Descriptor ID |
D048308
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| MeSH Number(s) |
D08.811.913.696.620.682.700.567.843.937 D12.644.360.450.835.800 D12.776.476.450.835.937
|
| Concept/Terms |
Mitogen-Activated Protein Kinase 14- Mitogen-Activated Protein Kinase 14
- Mitogen Activated Protein Kinase 14
- CSAID-Binding Protein
- CSAID Binding Protein
- Kinase CSBP
- CSBP, Kinase
- p38alpha MAP Kinase
- MAP Kinase, p38alpha
- p38alphaMAPK
- Cytokine Suppressive Anti-inflammatory Drug Binding Protein
- Cytokine Suppressive Anti inflammatory Drug Binding Protein
- Mxi2 Protein
- MAX-Interacting Protein 2
- MAX Interacting Protein 2
- p38alpha Mitogen-Activated Protein Kinase
- p38alpha Mitogen Activated Protein Kinase
- MAPK14
- Stress-activated protein kinase 2a
- Stress activated protein kinase 2a
- SAPK2a
- MAPK14 Mitogen-Activated Protein Kinase
- MAPK14 Mitogen Activated Protein Kinase
|
Below are MeSH descriptors whose meaning is more general than "Mitogen-Activated Protein Kinase 14".
Below are MeSH descriptors whose meaning is more specific than "Mitogen-Activated Protein Kinase 14".
This graph shows the total number of publications written about "Mitogen-Activated Protein Kinase 14" by people in this website by year, and whether "Mitogen-Activated Protein Kinase 14" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2007 | 1 | 0 | 1 |
| 2010 | 0 | 1 | 1 |
| 2011 | 0 | 1 | 1 |
| 2014 | 2 | 0 | 2 |
| 2016 | 1 | 0 | 1 |
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Below are the most recent publications written about "Mitogen-Activated Protein Kinase 14" by people in Profiles.
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Haldane A, Flynn WF, He P, Vijayan RS, Levy RM. Structural propensities of kinase family proteins from a Potts model of residue co-variation. Protein Sci. 2016 08; 25(8):1378-84.
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Greenblatt MB, Kim JM, Oh H, Park KH, Choo MK, Sano Y, Tye CE, Skobe Z, Davis RJ, Park JM, Bei M, Glimcher LH, Shim JH. p38a MAPK is required for tooth morphogenesis and enamel secretion. J Biol Chem. 2015 Jan 02; 290(1):284-95.
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Waterworth DM, Li L, Scott R, Warren L, Gillson C, Aponte J, Sarov-Blat L, Sprecher D, Dupuis J, Reiner A, Psaty BM, Tracy RP, Lin H, McPherson R, Chissoe S, Wareham N, Ehm MG. A low-frequency variant in MAPK14 provides mechanistic evidence of a link with myeloperoxidase: a prognostic cardiovascular risk marker. J Am Heart Assoc. 2014 Aug 27; 3(4).
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Tang WH, Stitham J, Gleim S, Di Febbo C, Porreca E, Fava C, Tacconelli S, Capone M, Evangelista V, Levantesi G, Wen L, Martin K, Minuz P, Rade J, Patrignani P, Hwa J. Glucose and collagen regulate human platelet activity through aldose reductase induction of thromboxane. J Clin Invest. 2011 Nov; 121(11):4462-76.
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Greenblatt MB, Shim JH, Zou W, Sitara D, Schweitzer M, Hu D, Lotinun S, Sano Y, Baron R, Park JM, Arthur S, Xie M, Schneider MD, Zhai B, Gygi S, Davis R, Glimcher LH. The p38 MAPK pathway is essential for skeletogenesis and bone homeostasis in mice. J Clin Invest. 2010 Jul; 120(7):2457-73.
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Kennedy NJ, Cellurale C, Davis RJ. A radical role for p38 MAPK in tumor initiation. Cancer Cell. 2007 Feb; 11(2):101-3.
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Aouadi M, Laurent K, Prot M, Le Marchand-Brustel Y, Bin?truy B, Bost F. Inhibition of p38MAPK increases adipogenesis from embryonic to adult stages. Diabetes. 2006 Feb; 55(2):281-9.