 Interleukin-2
"Interleukin-2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A soluble substance elaborated by antigen- or mitogen-stimulated T-LYMPHOCYTES which induces DNA synthesis in naive lymphocytes.
| Descriptor ID |
D007376
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| MeSH Number(s) |
D12.644.276.374.465.502 D12.644.276.374.480.372 D12.776.467.374.465.502 D12.776.467.374.480.372 D23.529.374.465.502 D23.529.374.480.372
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| Concept/Terms |
Interleukin-2- Interleukin-2
- Interleukin 2
- IL-2
- IL2
- TCGF
- Interleukine 2
- Lymphocyte Mitogenic Factor
- Mitogenic Factor, Lymphocyte
- T-Cell Growth Factor
- T Cell Growth Factor
- T-Cell Stimulating Factor
- T Cell Stimulating Factor
- Thymocyte Stimulating Factor
- Interleukin II
Ro-23-6019- Ro-23-6019
- Ro 23 6019
- Ro236019
- Ro-236019
- Ro 236019
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Below are MeSH descriptors whose meaning is more general than "Interleukin-2".
Below are MeSH descriptors whose meaning is more specific than "Interleukin-2".
This graph shows the total number of publications written about "Interleukin-2" by people in this website by year, and whether "Interleukin-2" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1981 | 2 | 0 | 2 | | 1982 | 1 | 3 | 4 | | 1983 | 1 | 4 | 5 | | 1984 | 2 | 2 | 4 | | 1985 | 1 | 1 | 2 | | 1986 | 0 | 1 | 1 | | 1987 | 2 | 2 | 4 | | 1988 | 1 | 1 | 2 | | 1990 | 3 | 2 | 5 | | 1991 | 4 | 8 | 12 | | 1992 | 1 | 3 | 4 | | 1993 | 3 | 2 | 5 | | 1994 | 1 | 4 | 5 | | 1995 | 1 | 2 | 3 | | 1996 | 2 | 7 | 9 | | 1997 | 1 | 5 | 6 | | 1998 | 2 | 1 | 3 | | 1999 | 1 | 5 | 6 | | 2000 | 1 | 1 | 2 | | 2001 | 1 | 1 | 2 | | 2002 | 0 | 7 | 7 | | 2003 | 2 | 3 | 5 | | 2004 | 0 | 7 | 7 | | 2005 | 3 | 1 | 4 | | 2007 | 2 | 2 | 4 | | 2008 | 0 | 1 | 1 | | 2009 | 2 | 2 | 4 | | 2010 | 0 | 3 | 3 | | 2012 | 0 | 2 | 2 | | 2013 | 1 | 0 | 1 | | 2014 | 2 | 4 | 6 | | 2015 | 1 | 3 | 4 | | 2016 | 0 | 2 | 2 |
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Below are the most recent publications written about "Interleukin-2" by people in Profiles.
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Chang HH, Liu GY, Dwivedi N, Sun B, Okamoto Y, Kinslow JD, Deane KD, Demoruelle MK, Norris JM, Thompson PR, Sparks JA, Rao DA, Karlson EW, Hung HC, Holers VM, Ho IC. A molecular signature of preclinical rheumatoid arthritis triggered by dysregulated PTPN22. JCI Insight. 2016 10 20; 1(17):e90045.
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Jayaraman P, Jacques MK, Zhu C, Steblenko KM, Stowell BL, Madi A, Anderson AC, Kuchroo VK, Behar SM. TIM3 Mediates T Cell Exhaustion during Mycobacterium tuberculosis Infection. PLoS Pathog. 2016 Mar; 12(3):e1005490.
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Friedline RH, Ko HJ, Jung DY, Lee Y, Bortell R, Dagdeviren S, Patel PR, Hu X, Inashima K, Kearns C, Tsitsilianos N, Shafiq U, Shultz LD, Lee KW, Greiner DL, Kim JK. Genetic ablation of lymphocytes and cytokine signaling in nonobese diabetic mice prevents diet-induced obesity and insulin resistance. FASEB J. 2016 Mar; 30(3):1328-38.
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Wu T, Shin HM, Moseman EA, Ji Y, Huang B, Harly C, Sen JM, Berg LJ, Gattinoni L, McGavern DB, Schwartzberg PL. TCF1 Is Required for the T Follicular Helper Cell Response to Viral Infection. Cell Rep. 2015 Sep 29; 12(12):2099-110.
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Massari F, Santoni M, Ciccarese C, Santini D. The immunocheckpoints in modern oncology: the next 15 years. Expert Opin Biol Ther. 2015 Jul; 15(7):917-21.
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Lee J, Martinez N, West K, Kornfeld H. Differential adjuvant activities of TLR7 and TLR9 agonists inversely correlate with nitric oxide and PGE2 production. PLoS One. 2015; 10(4):e0123165.
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Nobles C, Bertone-Johnson ER, Ronnenberg AG, Faraj JM, Zagarins S, Takashima-Uebelhoer BB, Whitcomb BW. Correlation of urine and plasma cytokine levels among reproductive-aged women. Eur J Clin Invest. 2015 May; 45(5):460-5.
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McKinstry KK, Strutt TM, Bautista B, Zhang W, Kuang Y, Cooper AM, Swain SL. Effector CD4 T-cell transition to memory requires late cognate interactions that induce autocrine IL-2. Nat Commun. 2014 Nov 05; 5:5377.
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Keck S, Schmaler M, Ganter S, Wyss L, Oberle S, Huseby ES, Zehn D, King CG. Antigen affinity and antigen dose exert distinct influences on CD4 T-cell differentiation. Proc Natl Acad Sci U S A. 2014 Oct 14; 111(41):14852-7.
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Youk H, Lim WA. Sending mixed messages for cell population control. Cell. 2014 Aug 28; 158(5):973-975.
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