5' Untranslated Regions

"5' Untranslated Regions" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

The sequence at the 5' end of the messenger RNA that does not code for product. This sequence contains the ribosome binding site and other transcription and translation regulating sequences.

Descriptor ID	D020121
MeSH Number(s)	D13.444.735.544.875.885 D13.444.735.790.878.885 G05.360.340.024.220.880.885 G05.360.340.024.340.137.910.885
Concept/Terms	5' Untranslated Regions 5' Untranslated Regions 5' Untranslated Region Region, 5' Untranslated Regions, 5' Untranslated Untranslated Region, 5' Untranslated Regions, 5' 5'UTR 5'UTRs Leader Sequences, mRNA Leader Sequence, mRNA Sequence, mRNA Leader Sequences, mRNA Leader mRNA Leader Sequence mRNA Leader Sequences 5' UTR 5' UTRs UTR, 5' UTRs, 5' Leader mRNA Sequences Leader mRNA Sequence Sequence, Leader mRNA Sequences, Leader mRNA mRNA Sequence, Leader mRNA Sequences, Leader

Below are MeSH descriptors whose meaning is more general than "5' Untranslated Regions".

Chemicals and Drugs [D]
Nucleic Acids, Nucleotides, and Nucleosides [D13]
Nucleic Acids [D13.444]
RNA [D13.444.735]
RNA, Messenger [D13.444.735.544]
Untranslated Regions [D13.444.735.544.875]
5' Untranslated Regions [D13.444.735.544.875.885]
RNA, Untranslated [D13.444.735.790]
Untranslated Regions [D13.444.735.790.878]
5' Untranslated Regions [D13.444.735.790.878.885]
Biological Sciences [G]
Genetic Phenomena [G05]
Genetic Structures [G05.360]
Genome [G05.360.340]
Genome Components [G05.360.340.024]
DNA, Intergenic [G05.360.340.024.220]
Untranslated Regions [G05.360.340.024.220.880]
5' Untranslated Regions [G05.360.340.024.220.880.885]
Genes [G05.360.340.024.340]
Gene Components [G05.360.340.024.340.137]
Untranslated Regions [G05.360.340.024.340.137.910]
5' Untranslated Regions [G05.360.340.024.340.137.910.885]

Below are MeSH descriptors whose meaning is related to "5' Untranslated Regions".

Below are MeSH descriptors whose meaning is more specific than "5' Untranslated Regions".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "5' Untranslated Regions" by people in this website by year, and whether "5' Untranslated Regions" was a major or minor topic of these publications.

Bar chart showing 19 publications over 14 distinct years, with a maximum of 3 publications in 2017

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2002	0	1	1
2003	0	1	1
2004	0	1	1
2005	0	2	2
2009	2	0	2
2011	1	0	1
2012	1	0	1
2013	0	1	1
2014	1	0	1
2015	1	0	1
2016	1	0	1
2017	2	1	3
2019	1	0	1
2021	0	2	2

Below are the most recent publications written about "5' Untranslated Regions" by people in Profiles.

Blakemore RJ, Burnett C, Swanson C, Kharytonchyk S, Telesnitsky A, Munro JB. Stability and conformation of the dimeric HIV-1 genomic RNA 5'UTR. Biophys J. 2021 11 02; 120(21):4874-4890.

View in: PubMed
Ilbay O, Nelson C, Ambros V. C.?elegans LIN-28 controls temporal cell fate progression by regulating LIN-46 expression via the 5' UTR of lin-46 mRNA. Cell Rep. 2021 09 07; 36(10):109670.

View in: PubMed
Brigham BS, Kitzrow JP, Reyes JC, Musier-Forsyth K, Munro JB. Intrinsic conformational dynamics of the HIV-1 genomic RNA 5'UTR. Proc Natl Acad Sci U S A. 2019 05 21; 116(21):10372-10381.

View in: PubMed
Na CH, Barbhuiya MA, Kim MS, Verbruggen S, Eacker SM, Pletnikova O, Troncoso JC, Halushka MK, Menschaert G, Overall CM, Pandey A. Discovery of noncanonical translation initiation sites through mass spectrometric analysis of protein N termini. Genome Res. 2018 01; 28(1):25-36.

View in: PubMed
Protasova MS, Gusev FE, Grigorenko AP, Kuznetsova IL, Rogaev EI, Andreeva TV. Quantitative Analysis of L1-Retrotransposons in Alzheimer's Disease and Aging. Biochemistry (Mosc). 2017 Aug; 82(8):962-971.

View in: PubMed
Kalantari P, Harandi OF, Agarwal S, Rus F, Kurt-Jones EA, Fitzgerald KA, Caffrey DR, Golenbock DT. miR-718 represses proinflammatory cytokine production through targeting phosphatase and tensin homolog (PTEN). J Biol Chem. 2017 04 07; 292(14):5634-5644.

View in: PubMed
Cenik C, Chua HN, Singh G, Akef A, Snyder MP, Palazzo AF, Moore MJ, Roth FP. A common class of transcripts with 5'-intron depletion, distinct early coding sequence features, and N1-methyladenosine modification. RNA. 2017 03; 23(3):270-283.

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Martinez M, Hinojosa M, Trombly D, Morin V, Stein J, Stein G, Javed A, Gutierrez SE. Transcriptional Auto-Regulation of RUNX1 P1 Promoter. PLoS One. 2016; 11(2):e0149119.

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Kim EZ, Wespiser AR, Caffrey DR. The domain structure and distribution of Alu elements in long noncoding RNAs and mRNAs. RNA. 2016 Feb; 22(2):254-64.

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Wolfe AL, Singh K, Zhong Y, Drewe P, Rajasekhar VK, Sanghvi VR, Mavrakis KJ, Jiang M, Roderick JE, Van der Meulen J, Schatz JH, Rodrigo CM, Zhao C, Rondou P, de Stanchina E, Teruya-Feldstein J, Kelliher MA, Speleman F, Porco JA, Pelletier J, R?tsch G, Wendel HG. RNA G-quadruplexes cause eIF4A-dependent oncogene translation in cancer. Nature. 2014 Sep 04; 513(7516):65-70.

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