 Glycogen Synthase Kinase 3
"Glycogen Synthase Kinase 3" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A glycogen synthase kinase that was originally described as a key enzyme involved in glycogen metabolism. It regulates a diverse array of functions such as CELL DIVISION, microtubule function and APOPTOSIS.
| Descriptor ID |
D038362
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| MeSH Number(s) |
D05.500.117.875 D08.811.913.696.620.682.700.429.500 D08.811.913.696.620.682.700.646.625 D12.644.360.300.500 D12.776.476.081.875 D12.776.476.300.500
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Glycogen Synthase Kinase 3".
Below are MeSH descriptors whose meaning is more specific than "Glycogen Synthase Kinase 3".
This graph shows the total number of publications written about "Glycogen Synthase Kinase 3" by people in this website by year, and whether "Glycogen Synthase Kinase 3" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 0 | 2 | 2 | | 2001 | 0 | 1 | 1 | | 2002 | 1 | 1 | 2 | | 2004 | 1 | 0 | 1 | | 2005 | 1 | 6 | 7 | | 2006 | 0 | 2 | 2 | | 2007 | 1 | 0 | 1 | | 2008 | 3 | 0 | 3 | | 2009 | 0 | 1 | 1 | | 2010 | 1 | 1 | 2 | | 2011 | 0 | 1 | 1 | | 2013 | 0 | 3 | 3 | | 2014 | 2 | 1 | 3 | | 2015 | 2 | 0 | 2 | | 2016 | 0 | 1 | 1 |
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Below are the most recent publications written about "Glycogen Synthase Kinase 3" by people in Profiles.
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Orme MH, Liccardi G, Moderau N, Feltham R, Wicky-John S, Tenev T, Aram L, Wilson R, Bianchi K, Morris O, Monteiro Domingues C, Robertson D, Tare M, Wepf A, Williams D, Bergmann A, Gstaiger M, Arama E, Ribeiro PS, Meier P. The unconventional myosin CRINKLED and its mammalian orthologue MYO7A regulate caspases in their signalling roles. Nat Commun. 2016 Mar 10; 7:10972.
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Jurczyk A, Nowosielska A, Przewozniak N, Aryee KE, DiIorio P, Blodgett D, Yang C, Campbell-Thompson M, Atkinson M, Shultz L, Rittenhouse A, Harlan D, Greiner D, Bortell R. Beyond the brain: disrupted in schizophrenia 1 regulates pancreatic ß-cell function via glycogen synthase kinase-3ß. FASEB J. 2016 Feb; 30(2):983-93.
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Arnold AC, Robertson D. Defective Wnt Signaling: A Potential Contributor to Cardiometabolic Disease? Diabetes. 2015 Oct; 64(10):3342-4.
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Jones CI, Sage T, Moraes LA, Vaiyapuri S, Hussain U, Tucker KL, Barrett NE, Gibbins JM. Platelet endothelial cell adhesion molecule-1 inhibits platelet response to thrombin and von Willebrand factor by regulating the internalization of glycoprotein Ib via AKT/glycogen synthase kinase-3/dynamin and integrin aIIbß3. Arterioscler Thromb Vasc Biol. 2014 Sep; 34(9):1968-76.
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Landis J, Shaw LM. Insulin receptor substrate 2-mediated phosphatidylinositol 3-kinase signaling selectively inhibits glycogen synthase kinase 3ß to regulate aerobic glycolysis. J Biol Chem. 2014 Jun 27; 289(26):18603-13.
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Zhang W, Xiao H, Parkin KL. Apoptosis in MCF-7 breast cancer cells induced by S-alkenylmercaptocysteine (CySSR) species derived from Allium tissues in combination with sodium selenite. Food Chem Toxicol. 2014 Jun; 68:1-10.
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Guendel I, Iordanskiy S, Van Duyne R, Kehn-Hall K, Saifuddin M, Das R, Jaworski E, Sampey GC, Senina S, Shultz L, Narayanan A, Chen H, Lepene B, Zeng C, Kashanchi F. Novel neuroprotective GSK-3ß inhibitor restricts Tat-mediated HIV-1 replication. J Virol. 2014 Jan; 88(2):1189-208.
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Shim JH, Greenblatt MB, Zou W, Huang Z, Wein MN, Brady N, Hu D, Charron J, Brodkin HR, Petsko GA, Zaller D, Zhai B, Gygi S, Glimcher LH, Jones DC. Schnurri-3 regulates ERK downstream of WNT signaling in osteoblasts. J Clin Invest. 2013 Sep; 123(9):4010-22.
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Chen Y, Yu D, Zhang C, Shang B, He H, Chen J, Zhang H, Zhao W, Wang Z, Xu X, Zhen Y, Shao RG. Lidamycin inhibits tumor initiating cells of hepatocellular carcinoma Huh7 through GSK3ß/ß-catenin pathway. Mol Carcinog. 2015 Jan; 54(1):1-8.
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Li Z, Rana TM. A kinase inhibitor screen identifies small-molecule enhancers of reprogramming and iPS cell generation. Nat Commun. 2012; 3:1085.
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