DNA, Satellite
"DNA, Satellite" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Highly repetitive DNA sequences found in HETEROCHROMATIN, mainly near centromeres. They are composed of simple sequences (very short) (see MINISATELLITE REPEATS) repeated in tandem many times to form large blocks of sequence. Additionally, following the accumulation of mutations, these blocks of repeats have been repeated in tandem themselves. The degree of repetition is on the order of 1000 to 10 million at each locus. Loci are few, usually one or two per chromosome. They were called satellites since in density gradients, they often sediment as distinct, satellite bands separate from the bulk of genomic DNA owing to a distinct BASE COMPOSITION.
Descriptor ID |
D004276
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MeSH Number(s) |
D13.444.308.480 G02.111.570.080.708.800.150 G05.360.080.708.800.150 G05.360.340.024.220.150 G05.360.340.024.850.150
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Concept/Terms |
DNA, Satellite- DNA, Satellite
- Satellite DNA
- DNAs, Satellite
- Satellite DNAs
Satellite I DNA- Satellite I DNA
- DNA, Satellite I
- DNAs, Satellite I
- I DNA, Satellite
- I DNAs, Satellite
- Satellite I DNAs
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Below are MeSH descriptors whose meaning is more general than "DNA, Satellite".
- Chemicals and Drugs [D]
- Nucleic Acids, Nucleotides, and Nucleosides [D13]
- Nucleic Acids [D13.444]
- DNA [D13.444.308]
- DNA, Satellite [D13.444.308.480]
- Biological Sciences [G]
- Chemical Phenomena [G02]
- Biochemical Phenomena [G02.111]
- Molecular Structure [G02.111.570]
- Base Sequence [G02.111.570.080]
- Repetitive Sequences, Nucleic Acid [G02.111.570.080.708]
- Tandem Repeat Sequences [G02.111.570.080.708.800]
- DNA, Satellite [G02.111.570.080.708.800.150]
- Genetic Phenomena [G05]
- Genetic Structures [G05.360]
- Base Sequence [G05.360.080]
- Repetitive Sequences, Nucleic Acid [G05.360.080.708]
- Tandem Repeat Sequences [G05.360.080.708.800]
- DNA, Satellite [G05.360.080.708.800.150]
- Genome [G05.360.340]
- Genome Components [G05.360.340.024]
- DNA, Intergenic [G05.360.340.024.220]
- DNA, Satellite [G05.360.340.024.220.150]
- Tandem Repeat Sequences [G05.360.340.024.850]
- DNA, Satellite [G05.360.340.024.850.150]
Below are MeSH descriptors whose meaning is more specific than "DNA, Satellite".
This graph shows the total number of publications written about "DNA, Satellite" by people in this website by year, and whether "DNA, Satellite" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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1989 | 1 | 0 | 1 | 1990 | 1 | 0 | 1 | 1992 | 1 | 0 | 1 | 1993 | 1 | 0 | 1 | 1994 | 0 | 1 | 1 | 1996 | 0 | 1 | 1 | 1998 | 1 | 0 | 1 | 2006 | 0 | 1 | 1 | 2013 | 0 | 1 | 1 | 2014 | 1 | 0 | 1 |
To return to the timeline, click here.
Below are the most recent publications written about "DNA, Satellite" by people in Profiles.
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Pederson T. Repeated TALEs: visualizing DNA sequence localization and chromosome dynamics in live cells. Nucleus. 2014 Jan-Feb; 5(1):28-31.
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Swanson EC, Manning B, Zhang H, Lawrence JB. Higher-order unfolding of satellite heterochromatin is a consistent and early event in cell senescence. J Cell Biol. 2013 Dec 23; 203(6):929-42.
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Nusbaum C, Mikkelsen TS, Zody MC, Asakawa S, Taudien S, Garber M, Kodira CD, Schueler MG, Shimizu A, Whittaker CA, Chang JL, Cuomo CA, Dewar K, FitzGerald MG, Yang X, Allen NR, Anderson S, Asakawa T, Blechschmidt K, Bloom T, Borowsky ML, Butler J, Cook A, Corum B, DeArellano K, DeCaprio D, Dooley KT, Dorris L, Engels R, Glöckner G, Hafez N, Hagopian DS, Hall JL, Ishikawa SK, Jaffe DB, Kamat A, Kudoh J, Lehmann R, Lokitsang T, Macdonald P, Major JE, Matthews CD, Mauceli E, Menzel U, Mihalev AH, Minoshima S, Murayama Y, Naylor JW, Nicol R, Nguyen C, O'Leary SB, O'Neill K, Parker SC, Polley A, Raymond CK, Reichwald K, Rodriguez J, Sasaki T, Schilhabel M, Siddiqui R, Smith CL, Sneddon TP, Talamas JA, Tenzin P, Topham K, Venkataraman V, Wen G, Yamazaki S, Young SK, Zeng Q, Zimmer AR, Rosenthal A, Birren BW, Platzer M, Shimizu N, Lander ES. DNA sequence and analysis of human chromosome 8. Nature. 2006 Jan 19; 439(7074):331-5.
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Elgar G, Clark MS, Meek S, Smith S, Warner S, Edwards YJ, Bouchireb N, Cottage A, Yeo GS, Umrania Y, Williams G, Brenner S. Generation and analysis of 25 Mb of genomic DNA from the pufferfish Fugu rubripes by sequence scanning. Genome Res. 1999 Oct; 9(10):960-71.
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Solov'ev IV, Iurov IuB, Vorsanova SG, Marcais B, Rogaev EI, Kapanadze BI, Brodianskii VM, Iankovskii NK, Roizes G. [Study of alpha-satellite DNA in cosmid libraries, specific for chromosomes 13, 21, and 22, using fluorescence in situ hybridization]. Genetika. 1998 Nov; 34(11):1470-9.
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Edwards YJ, Elgar G, Clark MS, Bishop MJ. The identification and characterization of microsatellites in the compact genome of the Japanese pufferfish, Fugu rubripes: perspectives in functional and comparative genomic analyses. J Mol Biol. 1998 May 15; 278(4):843-54.
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Heine D, Passmore HC, Patel V, Shultz LD, Ward-Bailey P, Cook SA, Davisson MT. Effect of the mouse scid mutation on meiotic recombination. Mamm Genome. 1996 Jul; 7(7):497-500.
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Couch FJ, Kiousis S, Castilla LH, Xu J, Chandrasekharappa SC, Chamberlain JS, Collins FS, Weber BL. Characterization of 10 new polymorphic dinucleotide repeats and generation of a high-density microsatellite-based physical map of the BRCA1 region of chromosome 17q21. Genomics. 1994 Dec; 24(3):419-24.
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Tupler R, Rogaeva E, Vaula G, Mortilla M, Lukiw W, Liang Y, Hancock R, Rogaev E, St George-Hyslop P. A highly informative microsatellite repeat polymorphism in intron 1 of the human amyloid precursor protein (APP) gene. Hum Mol Genet. 1993 May; 2(5):620.
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Rogaev E, Rogaeva E, Lukiw WJ, Vaula G, Liang Y, Hancock R, McLachlan DC, St George-Hyslop PH. An informative microsatellite repeat polymorphism in the human neurofilament light polypeptide (NEFL) gene. Hum Mol Genet. 1992 Dec; 1(9):781.
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