"DNA, Satellite" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Highly repetitive DNA sequences found in HETEROCHROMATIN, mainly near centromeres. They are composed of simple sequences (very short) (see MINISATELLITE REPEATS) repeated in tandem many times to form large blocks of sequence. Additionally, following the accumulation of mutations, these blocks of repeats have been repeated in tandem themselves. The degree of repetition is on the order of 1000 to 10 million at each locus. Loci are few, usually one or two per chromosome. They were called satellites since in density gradients, they often sediment as distinct, satellite bands separate from the bulk of genomic DNA owing to a distinct BASE COMPOSITION.
| Descriptor ID |
D004276
|
| MeSH Number(s) |
D13.444.308.480 G02.111.570.080.708.800.150 G05.360.080.708.800.150 G05.360.340.024.220.150 G05.360.340.024.850.150
|
| Concept/Terms |
DNA, Satellite- DNA, Satellite
- Satellite DNA
- DNAs, Satellite
- Satellite DNAs
Satellite I DNA- Satellite I DNA
- DNA, Satellite I
- DNAs, Satellite I
- I DNA, Satellite
- I DNAs, Satellite
- Satellite I DNAs
|
Below are MeSH descriptors whose meaning is more general than "DNA, Satellite".
- Chemicals and Drugs [D]
- Nucleic Acids, Nucleotides, and Nucleosides [D13]
- Nucleic Acids [D13.444]
- DNA [D13.444.308]
- DNA, Satellite [D13.444.308.480]
- Biological Sciences [G]
- Chemical Phenomena [G02]
- Biochemical Phenomena [G02.111]
- Molecular Structure [G02.111.570]
- Base Sequence [G02.111.570.080]
- Repetitive Sequences, Nucleic Acid [G02.111.570.080.708]
- Tandem Repeat Sequences [G02.111.570.080.708.800]
- DNA, Satellite [G02.111.570.080.708.800.150]
- Genetic Phenomena [G05]
- Genetic Structures [G05.360]
- Base Sequence [G05.360.080]
- Repetitive Sequences, Nucleic Acid [G05.360.080.708]
- Tandem Repeat Sequences [G05.360.080.708.800]
- DNA, Satellite [G05.360.080.708.800.150]
- Genome [G05.360.340]
- Genome Components [G05.360.340.024]
- DNA, Intergenic [G05.360.340.024.220]
- DNA, Satellite [G05.360.340.024.220.150]
- Tandem Repeat Sequences [G05.360.340.024.850]
- DNA, Satellite [G05.360.340.024.850.150]
Below are MeSH descriptors whose meaning is more specific than "DNA, Satellite".
This graph shows the total number of publications written about "DNA, Satellite" by people in this website by year, and whether "DNA, Satellite" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 |
| 1998 | 1 | 0 | 1 |
| 2006 | 0 | 1 | 1 |
| 2009 | 0 | 1 | 1 |
| 2013 | 0 | 1 | 1 |
| 2014 | 2 | 1 | 3 |
| 2016 | 1 | 0 | 1 |
| 2017 | 1 | 0 | 1 |
| 2018 | 3 | 0 | 3 |
| 2019 | 0 | 1 | 1 |
| 2024 | 1 | 0 | 1 |
| 2025 | 0 | 1 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "DNA, Satellite" by people in Profiles.
-
Hall LL, Smith KP, Lawrence JB. Emerging Functions of the Repeat Genome in Nuclear Structure: A View from the Human Karyotype. Annu Rev Genomics Hum Genet. 2025 08; 26(1):45-75.
-
Said I, Barbash DA, Clark AG. The Structure of Simple Satellite Variation in the Human Genome and Its Correlation With Centromere Ancestry. Genome Biol Evol. 2024 08 05; 16(8).
-
Lower SE, Dion-C?t? AM, Clark AG, Barbash DA. Special Issue: Repetitive DNA Sequences. Genes (Basel). 2019 11 06; 10(11).
-
Wei KH, Lower SE, Caldas IV, Sless TJS, Barbash DA, Clark AG. Variable Rates of Simple Satellite Gains across the Drosophila Phylogeny. Mol Biol Evol. 2018 04 01; 35(4):925-941.
-
McGurk MP, Barbash DA. Double insertion of transposable elements provides a substrate for the evolution of satellite DNA. Genome Res. 2018 05; 28(5):714-725.
-
Lower SS, McGurk MP, Clark AG, Barbash DA. Satellite DNA evolution: old ideas, new approaches. Curr Opin Genet Dev. 2018 04; 49:70-78.
-
Hall LL, Byron M, Carone DM, Whitfield TW, Pouliot GP, Fischer A, Jones P, Lawrence JB. Demethylated HSATII DNA and HSATII RNA Foci Sequester PRC1 and MeCP2 into Cancer-Specific Nuclear Bodies. Cell Rep. 2017 03 21; 18(12):2943-2956.
-
Ziccardi W, Zhao C, Shepelev V, Uralsky L, Alexandrov I, Andreeva T, Rogaev E, Bun C, Miller E, Putonti C, Doering J. Clusters of alpha satellite on human chromosome 21 are dispersed far onto the short arm and lack ancient layers. Chromosome Res. 2016 09; 24(3):421-36.
-
Wei KH, Grenier JK, Barbash DA, Clark AG. Correlated variation and population differentiation in satellite DNA abundance among lines of Drosophila melanogaster. Proc Natl Acad Sci U S A. 2014 Dec 30; 111(52):18793-8.
-
Satyaki PR, Cuykendall TN, Wei KH, Brideau NJ, Kwak H, Aruna S, Ferree PM, Ji S, Barbash DA. The Hmr and Lhr hybrid incompatibility genes suppress a broad range of heterochromatic repeats. PLoS Genet. 2014 Mar; 10(3):e1004240.