"G(M2) Ganglioside" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A glycosphingolipid that accumulates due to a deficiency of hexosaminidase A or B (BETA-N-ACETYLHEXOSAMINIDASES), or GM2 activator protein, resulting in GANGLIOSIDOSES, heredity metabolic disorders that include TAY-SACHS DISEASE and SANDHOFF DISEASE.
| Descriptor ID |
D005678
|
| MeSH Number(s) |
D09.400.410.420.025.475.400 D10.390.470.025.475.400 D10.570.877.360.025.475.400
|
| Concept/Terms |
G(M2) Ganglioside- G(M2) Ganglioside
- Ganglioside GM2
- GM2, Ganglioside
- Tay-Sachs Disease Ganglioside
- Ganglioside, Tay-Sachs Disease
- Tay Sachs Disease Ganglioside
|
Below are MeSH descriptors whose meaning is more general than "G(M2) Ganglioside".
Below are MeSH descriptors whose meaning is more specific than "G(M2) Ganglioside".
This graph shows the total number of publications written about "G(M2) Ganglioside" by people in this website by year, and whether "G(M2) Ganglioside" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2005 | 1 | 0 | 1 |
| 2015 | 0 | 1 | 1 |
| 2020 | 0 | 1 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "G(M2) Ganglioside" by people in Profiles.
-
Lahey HG, Webber CJ, Golebiowski D, Izzo CM, Horn E, Taghian T, Rodriguez P, Batista AR, Ellis LE, Hwang M, Martin DR, Gray-Edwards H, Sena-Esteves M. Pronounced Therapeutic Benefit of a Single Bidirectional AAV Vector Administered Systemically in Sandhoff Mice. Mol Ther. 2020 10 07; 28(10):2150-2160.
-
Rockwell HE, McCurdy VJ, Eaton SC, Wilson DU, Johnson AK, Randle AN, Bradbury AM, Gray-Edwards HL, Baker HJ, Hudson JA, Cox NR, Sena-Esteves M, Seyfried TN, Martin DR. AAV-mediated gene delivery in a feline model of Sandhoff disease corrects lysosomal storage in the central nervous system. ASN Neuro. 2015 Mar-Apr; 7(2).
-
Retter MW, Johnson JC, Peckham DW, Bannink JE, Bangur CS, Dresser K, Cai F, Foy TM, Fanger NA, Fanger GR, Woda B, Rock KL. Characterization of a proapoptotic antiganglioside GM2 monoclonal antibody and evaluation of its therapeutic effect on melanoma and small cell lung carcinoma xenografts. Cancer Res. 2005 Jul 15; 65(14):6425-34.