Stem Cell Factor

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"Stem Cell Factor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A hematopoietic growth factor and the ligand of the cell surface c-kit protein (PROTO-ONCOGENE PROTEINS C-KIT). It is expressed during embryogenesis and is a growth factor for a number of cell types including the MAST CELLS and the MELANOCYTES in addition to the HEMATOPOIETIC STEM CELLS.

Descriptor ID	D019089
MeSH Number(s)	D12.644.276.374.410.800 D12.776.467.374.410.800 D23.529.374.410.800
Concept/Terms	Stem Cell Factor Stem Cell Factor Steel Factor Mast Cell Growth Factor c-kit Ligand c kit Ligand kit Ligand

Below are MeSH descriptors whose meaning is more general than "Stem Cell Factor".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Peptides [D12.644]
Intercellular Signaling Peptides and Proteins [D12.644.276]
Cytokines [D12.644.276.374]
Hematopoietic Cell Growth Factors [D12.644.276.374.410]
Stem Cell Factor [D12.644.276.374.410.800]
Proteins [D12.776]
Intercellular Signaling Peptides and Proteins [D12.776.467]
Cytokines [D12.776.467.374]
Hematopoietic Cell Growth Factors [D12.776.467.374.410]
Stem Cell Factor [D12.776.467.374.410.800]
Biological Factors [D23]
Intercellular Signaling Peptides and Proteins [D23.529]
Cytokines [D23.529.374]
Hematopoietic Cell Growth Factors [D23.529.374.410]
Stem Cell Factor [D23.529.374.410.800]

Below are MeSH descriptors whose meaning is related to "Stem Cell Factor".

Below are MeSH descriptors whose meaning is more specific than "Stem Cell Factor".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Stem Cell Factor" by people in this website by year, and whether "Stem Cell Factor" was a major or minor topic of these publications.

Bar chart showing 16 publications over 10 distinct years, with a maximum of 3 publications in 2000

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1996	1	0	1
1998	1	1	2
1999	0	1	1
2000	0	3	3
2002	0	1	1
2004	0	2	2
2012	2	0	2
2016	1	1	2
2017	0	1	1
2018	0	1	1

Below are the most recent publications written about "Stem Cell Factor" by people in Profiles.

Riding RL, Richmond JM, Harris JE. Mouse Model for Human Vitiligo. Curr Protoc Immunol. 2019 02; 124(1):e63.

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Herring BP, Hoggatt AM, Gupta A, Griffith S, Nakeeb A, Choi JN, Idrees MT, Nowak T, Morris DL, Wo JM. Idiopathic gastroparesis is associated with specific transcriptional changes in the gastric muscularis externa. Neurogastroenterol Motil. 2018 04; 30(4):e13230.

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Bahal R, Ali McNeer N, Quijano E, Liu Y, Sulkowski P, Turchick A, Lu YC, Bhunia DC, Manna A, Greiner DL, Brehm MA, Cheng CJ, L?pez-Gir?ldez F, Ricciardi A, Beloor J, Krause DS, Kumar P, Gallagher PG, Braddock DT, Mark Saltzman W, Ly DH, Glazer PM. In vivo correction of anaemia in ?-thalassemic mice by ?PNA-mediated gene editing with nanoparticle delivery. Nat Commun. 2016 10 26; 7:13304.

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Jangalwe S, Shultz LD, Mathew A, Brehm MA. Improved B cell development in humanized NOD-scid IL2R?null mice transgenically expressing human stem cell factor, granulocyte-macrophage colony-stimulating factor and interleukin-3. Immun Inflamm Dis. 2016 12; 4(4):427-440.

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Takagi S, Saito Y, Hijikata A, Tanaka S, Watanabe T, Hasegawa T, Mochizuki S, Kunisawa J, Kiyono H, Koseki H, Ohara O, Saito T, Taniguchi S, Shultz LD, Ishikawa F. Membrane-bound human SCF/KL promotes in vivo human hematopoietic engraftment and myeloid differentiation. Blood. 2012 Mar 22; 119(12):2768-77.

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Brehm MA, Racki WJ, Leif J, Burzenski L, Hosur V, Wetmore A, Gott B, Herlihy M, Ignotz R, Dunn R, Shultz LD, Greiner DL. Engraftment of human HSCs in nonirradiated newborn NOD-scid IL2r? null mice is enhanced by transgenic expression of membrane-bound human SCF. Blood. 2012 Mar 22; 119(12):2778-88.

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Kang J, Der SD. Cytokine functions in the formative stages of a lymphocyte's life. Curr Opin Immunol. 2004 Apr; 16(2):180-90.

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Colvin GA, Lambert JF, Moore BE, Carlson JE, Dooner MS, Abedi M, Cerny J, Quesenberry PJ. Intrinsic hematopoietic stem cell/progenitor plasticity: Inversions. J Cell Physiol. 2004 Apr; 199(1):20-31.

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Cerny J, Dooner M, McAuliffe C, Habibian H, Stencil K, Berrios V, Reilly J, Carlson J, Cerny AM, d'Hondt L, Benoit B, Lambert JF, Colvin G, Nilsson S, Becker P, Quesenberry P. Homing of purified murine lymphohematopoietic stem cells: a cytokine-induced defect. J Hematother Stem Cell Res. 2002 Dec; 11(6):913-22.

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Chute JP, Saini A, Wells M, Clark W, Wu A, St Louis D, Blair P, Harlan D, Kaushal S. Preincubation with endothelial cell monolayers increases gene transfer efficiency into human bone marrow CD34(+)CD38(-) progenitor cells. Hum Gene Ther. 2000 Dec 10; 11(18):2515-28.

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