Species- or subspecies-specific DNA (including COMPLEMENTARY DNA; conserved genes, whole chromosomes, or whole genomes) used in hybridization studies in order to identify microorganisms, to measure DNA-DNA homologies, to group subspecies, etc. The DNA probe hybridizes with a specific mRNA, if present. Conventional techniques used for testing for the hybridization product include dot blot assays, Southern blot assays, and DNA:RNA hybrid-specific antibody tests. Conventional labels for the DNA probe include the radioisotope labels 32P and 125I and the chemical label biotin. The use of DNA probes provides a specific, sensitive, rapid, and inexpensive replacement for cell culture techniques for diagnosing infections.

Descriptor ID	D015342
MeSH Number(s)	D13.444.600.223 D27.505.259.750.600.223 D27.720.470.530.600.223
Concept/Terms	DNA Probes DNA Probes Probes, DNA DNA Hybridization Probes Hybridization Probes, DNA Probes, DNA Hybridization Whole Genomic DNA Probes Whole Genomic DNA Probes Gene Probes, DNA Gene Probes, DNA DNA Gene Probes Probes, DNA Gene Whole Chromosomal Probes Whole Chromosomal Probes Chromosomal Probes, Whole Probes, Whole Chromosomal Chromosomal Probes Chromosomal Probes Probes, Chromosomal Conserved Gene Probes Conserved Gene Probes Gene Probes, Conserved Probes, Conserved Gene

Below are MeSH descriptors whose meaning is more general than "DNA Probes".

Below are MeSH descriptors whose meaning is related to "DNA Probes".

Below are MeSH descriptors whose meaning is more specific than "DNA Probes".