"Bromodeoxyuridine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A nucleoside that substitutes for thymidine in DNA and thus acts as an antimetabolite. It causes breaks in chromosomes and has been proposed as an antiviral and antineoplastic agent. It has been given orphan drug status for use in the treatment of primary brain tumors.
| Descriptor ID |
D001973
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| MeSH Number(s) |
D03.383.742.680.852.300.150 D13.570.230.430.196 D13.570.685.852.300.150
|
| Concept/Terms |
Bromodeoxyuridine- Bromodeoxyuridine
- Bromouracil Deoxyriboside
- Deoxyriboside, Bromouracil
- 5-Bromo-2'-deoxyuridine
- 5 Bromo 2' deoxyuridine
- BrdU
- BUdR
- 5-Bromodeoxyuridine
- 5 Bromodeoxyuridine
- Broxuridine
|
Below are MeSH descriptors whose meaning is more general than "Bromodeoxyuridine".
Below are MeSH descriptors whose meaning is more specific than "Bromodeoxyuridine".
This graph shows the total number of publications written about "Bromodeoxyuridine" by people in this website by year, and whether "Bromodeoxyuridine" was a major or minor topic of these publications.
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Below are the most recent publications written about "Bromodeoxyuridine" by people in Profiles.
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Sharma RB, Darko C, Zheng X, Gablaski B, Alonso LC. DNA Damage Does Not Cause BrdU Labeling of Mouse or Human ?-Cells. Diabetes. 2019 05; 68(5):975-987.
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Miska J, Abdulreda MH, Devarajan P, Lui JB, Suzuki J, Pileggi A, Berggren PO, Chen Z. Real-time immune cell interactions in target tissue during autoimmune-induced damage and graft tolerance. J Exp Med. 2014 Mar 10; 211(3):441-56.
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Haddady S, Low HP, Billings-Gagliardi S, Riskind PN, Schwartz WJ. Pregnancy modulates precursor cell proliferation in a murine model of focal demyelination. Neuroscience. 2010 May 19; 167(3):656-64.
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Friedline RH, Brown DS, Nguyen H, Kornfeld H, Lee J, Zhang Y, Appleby M, Der SD, Kang J, Chambers CA. CD4+ regulatory T cells require CTLA-4 for the maintenance of systemic tolerance. J Exp Med. 2009 Feb 16; 206(2):421-34.
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Uetake Y, Loncarek J, Nordberg JJ, English CN, La Terra S, Khodjakov A, Sluder G. Cell cycle progression and de novo centriole assembly after centrosomal removal in untransformed human cells. J Cell Biol. 2007 Jan 15; 176(2):173-82.
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Qu Q, Crandall JE, Luo T, McCaffery PJ, Smith FI. Defects in tangential neuronal migration of pontine nuclei neurons in the Largemyd mouse are associated with stalled migration in the ventrolateral hindbrain. Eur J Neurosci. 2006 Jun; 23(11):2877-86.
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Alonso L, Okada H, Pasolli HA, Wakeham A, You-Ten AI, Mak TW, Fuchs E. Sgk3 links growth factor signaling to maintenance of progenitor cells in the hair follicle. J Cell Biol. 2005 Aug 15; 170(4):559-70.
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Do K, Barnard GF. Effect of concomitant polyethylene glycol and celecoxib on colonic aberrant crypt foci and tumors in F344 rats. Dig Dis Sci. 2005 Jul; 50(7):1304-11.
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Girgenrath M, Kostek CA, Miller JB. Diseased muscles that lack dystrophin or laminin-alpha2 have altered compositions and proliferation of mononuclear cell populations. BMC Neurol. 2005 Apr 07; 5(1):7.
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Roberson DW, Alosi JA, Cotanche DA. Direct transdifferentiation gives rise to the earliest new hair cells in regenerating avian auditory epithelium. J Neurosci Res. 2004 Nov 15; 78(4):461-71.