DNA Nucleotidylexotransferase
"DNA Nucleotidylexotransferase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A non-template-directed DNA polymerase normally found in vertebrate thymus and bone marrow. It catalyzes the elongation of oligo- or polydeoxynucleotide chains and is widely used as a tool in the differential diagnosis of acute leukemias in man. EC 2.7.7.31.
| Descriptor ID |
D004253
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| MeSH Number(s) |
D08.811.913.696.445.308.325
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| Concept/Terms |
DNA Nucleotidylexotransferase- DNA Nucleotidylexotransferase
- Nucleotidylexotransferase, DNA
- Terminal Deoxynucleotidyl Transferase
- Deoxynucleotidyl Transferase, Terminal
- Transferase, Terminal Deoxynucleotidyl
- Terminal Deoxyribonucleotidyl Transferase
- Deoxyribonucleotidyl Transferase, Terminal
- Transferase, Terminal Deoxyribonucleotidyl
- Desoxynucleotidyl Transferase
- Transferase, Desoxynucleotidyl
- Desoxynucleotidyltransferase
- Terminal Deoxyribonucleotidyltransferase
- Deoxyribonucleotidyltransferase, Terminal
- Deoxynucleotidyl Transferase
- Transferase, Deoxynucleotidyl
- Terminal Addition Enzyme
- Addition Enzyme, Terminal
- Enzyme, Terminal Addition
- Deoxynucleotidyltransferase
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Below are MeSH descriptors whose meaning is more general than "DNA Nucleotidylexotransferase".
Below are MeSH descriptors whose meaning is more specific than "DNA Nucleotidylexotransferase".
This graph shows the total number of publications written about "DNA Nucleotidylexotransferase" by people in this website by year, and whether "DNA Nucleotidylexotransferase" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 1 | 1 |
| 2003 | 0 | 1 | 1 |
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Below are the most recent publications written about "DNA Nucleotidylexotransferase" by people in Profiles.
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Schrader CE, Bradley SP, Vardo J, Mochegova SN, Flanagan E, Stavnezer J. Mutations occur in the Ig Smu region but rarely in Sgamma regions prior to class switch recombination. EMBO J. 2003 Nov 03; 22(21):5893-903.
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Zhang X, Giangreco L, Broome HE, Dargan CM, Swain SL. Control of CD4 effector fate: transforming growth factor beta 1 and interleukin 2 synergize to prevent apoptosis and promote effector expansion. J Exp Med. 1995 Sep 01; 182(3):699-709.
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McKenna SD, Medlock ES, Greiner DL, Goldschneider I. A selective culture system for generating terminal deoxynucleotidyl transferase-positive lymphoid precursor cells in vitro. IV. Properties and developmental relationships of the lymphoid cells in the adherent and nonadherent compartments of the culture. Exp Hematol. 1994 Nov; 22(12):1164-70.
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Hunt SV, Medlock ES, Greiner DL, Goldschneider I, Opstelten D. Rat immunoglobulin genes have comparable patterns of JH rearrangement in normal peripheral B cells and in pre-B and cultured TdT+ cells from bone marrow. Adv Exp Med Biol. 1988; 237:63-8.
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Medlock ES, Goldschneider I, Greiner DL, Shultz L. Defective lymphopoiesis in the bone marrow of motheaten (me/me) and viable motheaten (mev/mev) mutant mice. II. Description of a microenvironmental defect for the generation of terminal deoxynucleotidyltransferase-positive bone marrow cells in vitro. J Immunol. 1987 Jun 01; 138(11):3590-7.
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Greiner DL, Goldschneider I, Komschlies KL, Medlock ES, Bollum FJ, Schultz L. Defective lymphopoiesis in bone marrow of motheaten (me/me) and viable motheaten (mev/mev) mutant mice. I. Analysis of development of prothymocytes, early B lineage cells, and terminal deoxynucleotidyl transferase-positive cells. J Exp Med. 1986 Oct 01; 164(4):1129-44.
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Barton RW, Greiner DL, Medlock ES, Goldschneider I. Phenotypic heterogeneity of Gross virus-induced thymic lymphomas in the rat: cellular origins and migratory properties. Cell Immunol. 1985 Aug; 94(1):113-21.
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Whittum J, Goldschneider I, Greiner D, Zurier R. Developmental abnormalities of terminal deoxynucleotidyl transferase positive bone marrow cells and thymocytes in New Zealand mice: effects of prostaglandin E1. J Immunol. 1985 Jul; 135(1):272-80.
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Greiner DL, Goldschneider I, Barton RW. Identification of thymocyte progenitors in hemopoietic tissues of the rat. II. Enrichment of functional prothymocytes on the fluorescence-activated cell sorter. J Exp Med. 1982 Nov 01; 156(5):1448-60.
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Bell R, Lillquist A, Abelson H, McCaffrey R. Chromatographic forms of terminal deoxynucleotidyl transferase in normal lymphoid cells and in leukemia cells at presentation and relapse. Leuk Res. 1982; 6(6):775-80.