"Calcium Signaling" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Signal transduction mechanisms whereby calcium mobilization (from outside the cell or from intracellular storage pools) to the cytoplasm is triggered by external stimuli. Calcium signals are often seen to propagate as waves, oscillations, spikes, sparks, or puffs. The calcium acts as an intracellular messenger by activating calcium-responsive proteins.
| Descriptor ID |
D020013
|
| MeSH Number(s) |
G02.111.820.800.100 G03.143.500.100 G04.835.800.100
|
| Concept/Terms |
Calcium Signaling- Calcium Signaling
- Calcium Signalings
- Signaling, Calcium
- Signalings, Calcium
Calcium Waves- Calcium Waves
- Calcium Wave
- Wave, Calcium
- Waves, Calcium
- Calcium Oscillations
- Calcium Oscillation
- Oscillation, Calcium
- Oscillations, Calcium
Calcium Spikes- Calcium Spikes
- Calcium Spike
- Spike, Calcium
- Spikes, Calcium
Calcium Puffs- Calcium Puffs
- Calcium Puff
- Puff, Calcium
- Puffs, Calcium
Calcium Sparks- Calcium Sparks
- Calcium Spark
- Spark, Calcium
- Sparks, Calcium
|
Below are MeSH descriptors whose meaning is more general than "Calcium Signaling".
Below are MeSH descriptors whose meaning is more specific than "Calcium Signaling".
This graph shows the total number of publications written about "Calcium Signaling" by people in this website by year, and whether "Calcium Signaling" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 1 | 0 | 1 |
| 1999 | 2 | 0 | 2 |
| 2000 | 3 | 0 | 3 |
| 2001 | 1 | 1 | 2 |
| 2002 | 1 | 3 | 4 |
| 2003 | 7 | 2 | 9 |
| 2004 | 4 | 4 | 8 |
| 2005 | 4 | 0 | 4 |
| 2006 | 6 | 1 | 7 |
| 2007 | 5 | 4 | 9 |
| 2008 | 6 | 2 | 8 |
| 2009 | 0 | 2 | 2 |
| 2010 | 2 | 1 | 3 |
| 2011 | 4 | 2 | 6 |
| 2012 | 4 | 3 | 7 |
| 2013 | 5 | 3 | 8 |
| 2014 | 2 | 5 | 7 |
| 2015 | 4 | 4 | 8 |
| 2016 | 0 | 2 | 2 |
| 2017 | 0 | 2 | 2 |
| 2018 | 6 | 3 | 9 |
| 2019 | 3 | 3 | 6 |
| 2020 | 1 | 2 | 3 |
| 2021 | 3 | 1 | 4 |
| 2023 | 0 | 1 | 1 |
| 2024 | 0 | 2 | 2 |
| 2025 | 3 | 3 | 6 |
| 2026 | 1 | 0 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Calcium Signaling" by people in Profiles.
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Suthar KP, Hounsell C, Fan Y, Bergmann A. Calcium signaling regulates apoptosis-induced proliferation in Drosophila. PLoS Biol. 2026 Jan; 24(1):e3003607.
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Tolomeo M, Magliocca V, Petrini S, Nisco A, Barbaro R, Lanza M, Piccione M, Giudetti AM, Massey K, Console L, Indiveri C, Zanier K, Bertini E, Persichini T, Compagnucci C, Colella M, Barile M. Altered dimerization of certain riboflavin transporter 2 mutants: a possible source of UPR, altered calcium signalling and mitochondrial derangements in RTD2. Arch Biochem Biophys. 2026 Jan; 775:110675.
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Stadinski BD, Mills EA, Humphries PA, Cleveland SB, Dow P, Murakami K, Li YR, Murakami M, Ono M, Au-Yeung BB, Morris GP, Z??iga-Pfl?cker JC, Campbell RA, Griffiths ER, Huseby ES, Lo WL. Age-dependent Zap70 expression in thymocytes regulates selection of the neonatal regulatory T cell repertoire. Nat Immunol. 2025 Dec; 26(12):2256-2269.
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Fissore RA, Lopes EM, Carpentiero F. Zebrafish sperm outsource activation to eggs' protease-activated receptors. PLoS Biol. 2025 Jun; 23(6):e3003214.
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Luque GM, Jablo?ski M, Schiavi-Ehrenhaus LJ, Del Prado RC, Balbach M, Romarowski A, Martin-Hidalgo D, Visconti PE, Krapf D, Darszon A, Krapf D, Buck J, Levin LR, Buffone MG. Bovine serum albumin-induced calcium influx triggers soluble adenylyl cyclase activation and cyclic AMP signalling pathways in mouse sperm capacitation. J Physiol. 2025 05; 603(9):2633-2653.
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Lee HC, Akizawa H, Fissore RA. Roles of the EF-hand domain of PLCZ1 in establishing species-specific Ca2+ oscillations in mouse and rat fertilization?. Biol Reprod. 2025 Apr 13; 112(4):663-674.
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S?nchez-C?rdenas C, Oliver EI, Ch?vez JC, Luque GM, Hern?ndez-Cruz A, Buffone MG, Darszon A, Visconti PE, Romarowski A. Ion channels and transporters involved in calcium flux regulation in mammalian sperm. Curr Top Dev Biol. 2025; 162:351-385.
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Zhang X, Zhang X, Cheng S, Fan X, Bao H, Zhou S, Ping J. Spatiotemporal Cell Control via High-Precision Electronic Regulation of Microenvironmental pH. Nano Lett. 2024 12 11; 24(49):15645-15651.
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Debold EP, Westerblad H. New insights into the cellular and molecular mechanisms of skeletal muscle fatigue: the Marion J. Siegman Award Lectureships. Am J Physiol Cell Physiol. 2024 Oct 01; 327(4):C946-C958.
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Akizawa H, Lopes EM, Fissore RA. Zn2+ is essential for Ca2+ oscillations in mouse eggs. Elife. 2023 12 15; 12.