 Toll-Like Receptor 8
"Toll-Like Receptor 8" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A pattern recognition receptor that recognizes GUANOSINE and URIDINE-rich single-stranded RNA.
| Descriptor ID |
D051200
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| MeSH Number(s) |
D12.776.543.750.705.910.500.800
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Toll-Like Receptor 8".
Below are MeSH descriptors whose meaning is more specific than "Toll-Like Receptor 8".
This graph shows the total number of publications written about "Toll-Like Receptor 8" by people in this website by year, and whether "Toll-Like Receptor 8" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 0 | 2 | 2 | | 2004 | 0 | 1 | 1 | | 2005 | 2 | 1 | 3 | | 2006 | 1 | 0 | 1 | | 2007 | 0 | 1 | 1 | | 2008 | 3 | 1 | 4 | | 2009 | 1 | 0 | 1 | | 2010 | 1 | 1 | 2 | | 2011 | 0 | 2 | 2 | | 2012 | 1 | 0 | 1 | | 2014 | 1 | 1 | 2 | | 2015 | 2 | 0 | 2 |
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Below are the most recent publications written about "Toll-Like Receptor 8" by people in Profiles.
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Eigenbrod T, Pelka K, Latz E, Kreikemeyer B, Dalpke AH. TLR8 Senses Bacterial RNA in Human Monocytes and Plays a Nonredundant Role for Recognition of Streptococcus pyogenes. J Immunol. 2015 Aug 1; 195(3):1092-9.
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Geyer M, Pelka K, Latz E. Synergistic activation of Toll-like receptor 8 by two RNA degradation products. Nat Struct Mol Biol. 2015 Feb; 22(2):99-101.
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Sarvestani ST, Stunden HJ, Behlke MA, Forster SC, McCoy CE, Tate MD, Ferrand J, Lennox KA, Latz E, Williams BR, Gantier MP. Sequence-dependent off-target inhibition of TLR7/8 sensing by synthetic microRNA inhibitors. Nucleic Acids Res. 2015 Jan; 43(2):1177-88.
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Wochal P, Rathinam VA, Dunne A, Carlson T, Kuang W, Seidl KJ, Hall JP, Lin LL, Collins M, Schattgen SA, MacKay CR, Fagundes CT, Carpenter S, Fitzgerald KA, O'Neill LA. TRIL is involved in cytokine production in the brain following Escherichia coli infection. J Immunol. 2014 Aug 15; 193(4):1911-9.
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Libraty DH, Zhang L, Woda M, Giaya K, Kathivu CL, Acosta LP, Tallo V, Segubre-Mercado E, Bautista A, Obcena A, Brion JD, Capeding RZ. Low adiposity during early infancy is associated with a low risk for developing dengue hemorrhagic fever: a preliminary model. PLoS One. 2014; 9(2):e88944.
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Libraty DH, Zhang L, Woda M, Acosta LP, Obcena A, Brion JD, Capeding RZ. Toll-like receptor induced pro-interleukin-1ß and interleukin-6 in monocytes are lower in healthy infants compared to adults. PLoS One. 2013; 8(10):e78018.
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Wang JP, Zhang L, Madera RF, Woda M, Libraty DH. Plasmacytoid dendritic cell interferon-a production to R-848 stimulation is decreased in male infants. BMC Immunol. 2012 Jul 06; 13:35.
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Pang M, Bala S, Kodys K, Catalano D, Szabo G. Inhibition of TLR8- and TLR4-induced Type I IFN induction by alcohol is different from its effects on inflammatory cytokine production in monocytes. BMC Immunol. 2011 Sep 30; 12:55.
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Jeudy S, Wardrop KE, Alessi A, Dominov JA. Bcl-2 inhibits the innate immune response during early pathogenesis of murine congenital muscular dystrophy. PLoS One. 2011; 6(8):e22369.
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Richardt-Pargmann D, Wechsler M, Krieg AM, Vollmer J, Jurk M. Positive T cell co-stimulation by TLR7/8 ligands is dependent on the cellular environment. Immunobiology. 2011 Jan-Feb; 216(1-2):12-23.
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