 Receptor, TIE-2
"Receptor, TIE-2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A TIE receptor tyrosine kinase that is found almost exclusively on ENDOTHELIAL CELLS. It is required for both normal embryonic vascular development (NEOVASCULARIZATION, PHYSIOLOGIC) and tumor angiogenesis (NEOVASCULARIZATION, PATHOLOGIC).
| Descriptor ID |
D042787
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| MeSH Number(s) |
D08.811.913.696.620.682.725.400.925.500 D12.776.543.750.060.687.500
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| Concept/Terms |
Receptor, TIE-2- Receptor, TIE-2
- Receptor, TIE 2
- TIE-2 Receptor
- Tek Receptor
- Receptor, Tek
- TIE2 Tyrosine Kinase
- Tyrosine Kinase, TIE2
- TIE-2-RTK
- Tie2 Receptor
- Receptor, Tie2
- Angiopoietin Receptor Tie-2
- Angiopoietin Receptor Tie 2
- Receptor Tie-2, Angiopoietin
- Tie-2, Angiopoietin Receptor
- TIE-2 Receptor Tyrosine Kinase
- TIE 2 Receptor Tyrosine Kinase
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Below are MeSH descriptors whose meaning is more general than "Receptor, TIE-2".
Below are MeSH descriptors whose meaning is more specific than "Receptor, TIE-2".
This graph shows the total number of publications written about "Receptor, TIE-2" by people in this website by year, and whether "Receptor, TIE-2" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 0 | 1 | 1 | | 2005 | 1 | 0 | 1 | | 2008 | 1 | 0 | 1 | | 2011 | 0 | 1 | 1 |
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Below are the most recent publications written about "Receptor, TIE-2" by people in Profiles.
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Mazzieri R, Pucci F, Moi D, Zonari E, Ranghetti A, Berti A, Politi LS, Gentner B, Brown JL, Naldini L, De Palma M. Targeting the ANG2/TIE2 axis inhibits tumor growth and metastasis by impairing angiogenesis and disabling rebounds of proangiogenic myeloid cells. Cancer Cell. 2011 Apr 12; 19(4):512-26.
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De Palma M, Mazzieri R, Politi LS, Pucci F, Zonari E, Sitia G, Mazzoleni S, Moi D, Venneri MA, Indraccolo S, Falini A, Guidotti LG, Galli R, Naldini L. Tumor-targeted interferon-alpha delivery by Tie2-expressing monocytes inhibits tumor growth and metastasis. Cancer Cell. 2008 Oct 7; 14(4):299-311.
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De Palma M, Venneri MA, Galli R, Sergi Sergi L, Politi LS, Sampaolesi M, Naldini L. Tie2 identifies a hematopoietic lineage of proangiogenic monocytes required for tumor vessel formation and a mesenchymal population of pericyte progenitors. Cancer Cell. 2005 Sep; 8(3):211-26.
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Shao R, Guo X. Human microvascular endothelial cells immortalized with human telomerase catalytic protein: a model for the study of in vitro angiogenesis. Biochem Biophys Res Commun. 2004 Sep 3; 321(4):788-94.
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