 Glucagon
"Glucagon" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A 29-amino acid pancreatic peptide derived from proglucagon which is also the precursor of intestinal GLUCAGON-LIKE PEPTIDES. Glucagon is secreted by PANCREATIC ALPHA CELLS and plays an important role in regulation of BLOOD GLUCOSE concentration, ketone metabolism, and several other biochemical and physiological processes. (From Gilman et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 9th ed, p1511)
| Descriptor ID |
D005934
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| MeSH Number(s) |
D06.472.699.587.469.500 D12.644.548.586.469.500
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| Concept/Terms |
Glucagon- Glucagon
- Proglucagon (33-61)
- HG-Factor
- HG Factor
- Hyperglycemic-Glycogenolytic Factor
- Hyperglycemic Glycogenolytic Factor
- Glucagon (1-29)
- Glukagon
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Below are MeSH descriptors whose meaning is more general than "Glucagon".
Below are MeSH descriptors whose meaning is more specific than "Glucagon".
This graph shows the total number of publications written about "Glucagon" by people in this website by year, and whether "Glucagon" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1989 | 0 | 2 | 2 | | 1990 | 0 | 1 | 1 | | 1991 | 1 | 1 | 2 | | 1996 | 0 | 1 | 1 | | 1999 | 0 | 1 | 1 | | 2000 | 1 | 0 | 1 | | 2003 | 1 | 1 | 2 | | 2008 | 1 | 0 | 1 | | 2011 | 1 | 1 | 2 | | 2014 | 1 | 3 | 4 | | 2015 | 0 | 1 | 1 |
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Below are the most recent publications written about "Glucagon" by people in Profiles.
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Andrzejewski D, Brown ML, Ungerleider N, Burnside A, Schneyer AL. Activins A and B Regulate Fate-Determining Gene Expression in Islet Cell Lines and Islet Cells From Male Mice. Endocrinology. 2015 Jul; 156(7):2440-50.
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Purwana I, Zheng J, Li X, Deurloo M, Son DO, Zhang Z, Liang C, Shen E, Tadkase A, Feng ZP, Li Y, Hasilo C, Paraskevas S, Bortell R, Greiner DL, Atkinson M, Prud'homme GJ, Wang Q. GABA promotes human ß-cell proliferation and modulates glucose homeostasis. Diabetes. 2014 Dec; 63(12):4197-205.
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Song WJ, Mondal P, Wolfe A, Alonso LC, Stamateris R, Ong BW, Lim OC, Yang KS, Radovick S, Novaira HJ, Farber EA, Farber CR, Turner SD, Hussain MA. Glucagon regulates hepatic kisspeptin to impair insulin secretion. Cell Metab. 2014 Apr 1; 19(4):667-81.
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Zachariah Tom R, Garcia-Roves PM, Sjögren RJ, Jiang LQ, Holmström MH, Deshmukh AS, Vieira E, Chibalin AV, Björnholm M, Zierath JR. Effects of AMPK activation on insulin sensitivity and metabolism in leptin-deficient ob/ob mice. Diabetes. 2014 May; 63(5):1560-71.
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Liu L, Nam M, Fan W, Akie TE, Hoaglin DC, Gao G, Keaney JF, Cooper MP. Nutrient sensing by the mitochondrial transcription machinery dictates oxidative phosphorylation. J Clin Invest. 2014 Feb; 124(2):768-84.
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Soleimanpour SA, Hirshberg B, Bunnell DJ, Sumner AE, Ader M, Remaley AT, Rother KI, Rickels MR, Harlan DM. Metabolic function of a suboptimal transplanted islet mass in nonhuman primates on rapamycin monotherapy. Cell Transplant. 2012; 21(6):1297-304.
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Hosseinnezhad A, Black RM, Aeddula NR, Adhikari D, Trivedi N. Glucagon-induced pheochromocytoma crisis. Endocr Pract. 2011 May-Jun; 17(3):e51-4.
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Cabrera O, Jacques-Silva MC, Speier S, Yang SN, Köhler M, Fachado A, Vieira E, Zierath JR, Kibbey R, Berman DM, Kenyon NS, Ricordi C, Caicedo A, Berggren PO. Glutamate is a positive autocrine signal for glucagon release. Cell Metab. 2008 Jun; 7(6):545-54.
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Farilla L, Bulotta A, Hirshberg B, Li Calzi S, Khoury N, Noushmehr H, Bertolotto C, Di Mario U, Harlan DM, Perfetti R. Glucagon-like peptide 1 inhibits cell apoptosis and improves glucose responsiveness of freshly isolated human islets. Endocrinology. 2003 Dec; 144(12):5149-58.
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Laforenza U, Gastaldi G, Rindi G, Leiter AB, Cova E, Marchetti A, Candusso ME, Autelli M, Orsenigo MN, Ventura U. PYY-Tag transgenic mice displaying abnormal (H+-K+)ATPase activity and gastric mucosal barrier impairment. Lab Invest. 2003 Jan; 83(1):47-54.
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