 PPAR gamma
"PPAR gamma" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A nuclear transcription factor. Heterodimerization with RETINOID X RECEPTOR ALPHA is important in regulation of GLUCOSE metabolism and CELL GROWTH PROCESSES. It is a target of THIAZOLIDINEDIONES for control of DIABETES MELLITUS.
| Descriptor ID |
D047495
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| MeSH Number(s) |
D12.776.260.698.239.588 D12.776.826.239.588 D12.776.930.669.239.588
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| Concept/Terms |
PPAR gamma- PPAR gamma
- PPARgamma
- Thiazolidinedione Receptor
- Receptor, Thiazolidinedione
- Peroxisome Proliferator-Activated Receptor gamma
- Peroxisome Proliferator Activated Receptor gamma
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Below are MeSH descriptors whose meaning is more general than "PPAR gamma".
Below are MeSH descriptors whose meaning is more specific than "PPAR gamma".
This graph shows the total number of publications written about "PPAR gamma" by people in this website by year, and whether "PPAR gamma" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 1 | 1 | 2 | | 2005 | 3 | 2 | 5 | | 2006 | 4 | 1 | 5 | | 2007 | 4 | 2 | 6 | | 2008 | 3 | 5 | 8 | | 2009 | 3 | 3 | 6 | | 2011 | 1 | 0 | 1 | | 2012 | 3 | 2 | 5 | | 2014 | 2 | 0 | 2 | | 2015 | 0 | 1 | 1 | | 2017 | 0 | 1 | 1 | | 2020 | 0 | 1 | 1 |
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Below are the most recent publications written about "PPAR gamma" by people in Profiles.
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Martinez Calejman C, Trefely S, Entwisle SW, Luciano A, Jung SM, Hsiao W, Torres A, Hung CM, Li H, Snyder NW, Villén J, Wellen KE, Guertin DA. mTORC2-AKT signaling to ATP-citrate lyase drives brown adipogenesis and de novo lipogenesis. Nat Commun. 2020 Jan 29; 11(1):575.
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Rothchild AC, Stowell B, Goyal G, Nunes-Alves C, Yang Q, Papavinasasundaram K, Sassetti CM, Dranoff G, Chen X, Lee J, Behar SM. Role of Granulocyte-Macrophage Colony-Stimulating Factor Production by T Cells during Mycobacterium tuberculosis Infection. MBio. 2017 10 24; 8(5).
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McCormick DL, Horn TL, Johnson WD, Peng X, Lubet RA, Steele VE. Suppression of Rat Oral Carcinogenesis by Agonists of Peroxisome Proliferator Activated Receptor ?. PLoS One. 2015; 10(10):e0141849.
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Hu YJ, Belaghzal H, Hsiao WY, Qi J, Bradner JE, Guertin DA, Sif S, Imbalzano AN. Transcriptional and post-transcriptional control of adipocyte differentiation by Jumonji domain-containing protein 6. Nucleic Acids Res. 2015 Sep 18; 43(16):7790-804.
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Kummer MP, Schwarzenberger R, Sayah-Jeanne S, Dubernet M, Walczak R, Hum DW, Schwartz S, Axt D, Heneka MT. Pan-PPAR modulation effectively protects APP/PS1 mice from amyloid deposition and cognitive deficits. Mol Neurobiol. 2015 Apr; 51(2):661-71.
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Bourke JE, Bai Y, Donovan C, Esposito JG, Tan X, Sanderson MJ. Novel small airway bronchodilator responses to rosiglitazone in mouse lung slices. Am J Respir Cell Mol Biol. 2014 Apr; 50(4):748-56.
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LeBlanc SE, Wu Q, Barutcu AR, Xiao H, Ohkawa Y, Imbalzano AN. The PPAR? locus makes long-range chromatin interactions with selected tissue-specific gene loci during adipocyte differentiation in a protein kinase A dependent manner. PLoS One. 2014; 9(1):e86140.
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Chan KH, Niu T, Ma Y, You NC, Song Y, Sobel EM, Hsu YH, Balasubramanian R, Qiao Y, Tinker L, Liu S. Common genetic variants in peroxisome proliferator-activated receptor-? (PPARG) and type 2 diabetes risk among Women's Health Initiative postmenopausal women. J Clin Endocrinol Metab. 2013 Mar; 98(3):E600-4.
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Yamanaka M, Ishikawa T, Griep A, Axt D, Kummer MP, Heneka MT. PPAR?/RXRa-induced and CD36-mediated microglial amyloid-ß phagocytosis results in cognitive improvement in amyloid precursor protein/presenilin 1 mice. J Neurosci. 2012 Nov 28; 32(48):17321-31.
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Mcilroy GD, Delibegovic M, Owen C, Stoney PN, Shearer KD, McCaffery PJ, Mody N. Fenretinide treatment prevents diet-induced obesity in association with major alterations in retinoid homeostatic gene expression in adipose, liver, and hypothalamus. Diabetes. 2013 Mar; 62(3):825-36.
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