Mediator Complex Subunit 1
"Mediator Complex Subunit 1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A mediator complex subunit that is believed to play a key role in the coactivation of nuclear receptor-activated transcription by the mediator complex. It interacts with a variety of nuclear receptors including RETINOIC ACID RECEPTORS; THYROID HORMONE RECEPTORS; VITAMIN D RECEPTORS; PEROXISOME PROLIFERATOR-ACTIVATED RECEPTORS; ESTROGEN RECEPTORS; and GLUCOCORTICOID RECEPTORS.
| Descriptor ID |
D056913
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| MeSH Number(s) |
D05.500.374.750 D12.644.360.024.309.750 D12.644.360.024.314.049 D12.776.157.057.072.750 D12.776.157.057.080.049 D12.776.476.024.388.750 D12.776.476.024.394.049 D12.776.660.551.750 D12.776.660.675.049 D12.776.930.617.049
|
| Concept/Terms |
Mediator Complex Subunit 1- Mediator Complex Subunit 1
- TRAP220
- Mediator of RNA Polymerase II Transcription Subunit 1
- p53 Regulatory Protein RB18A
- RB18A
- Vitamin D Receptor-Interacting Protein Complex Component DRIP205
- Vitamin D Receptor Interacting Protein Complex Component DRIP205
- Peroxisome Proliferator-Activated Receptor Binding Protein
- Peroxisome Proliferator Activated Receptor Binding Protein
- PPAR-Binding Protein
- PPAR Binding Protein
- Thyroid Receptor Interacting Protein 2
- TR-Associated Protein P220
- TR Associated Protein P220
- TRIP2 (Thyroid Receptor Interacting Protein 2)
- DRIP205
- Thyroid Hormone Receptor Associated Protein 220
|
Below are MeSH descriptors whose meaning is more general than "Mediator Complex Subunit 1".
Below are MeSH descriptors whose meaning is more specific than "Mediator Complex Subunit 1".
This graph shows the total number of publications written about "Mediator Complex Subunit 1" by people in this website by year, and whether "Mediator Complex Subunit 1" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2006 | 0 | 1 | 1 |
| 2008 | 0 | 1 | 1 |
| 2010 | 0 | 2 | 2 |
| 2016 | 0 | 1 | 1 |
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Below are the most recent publications written about "Mediator Complex Subunit 1" by people in Profiles.
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LeBlanc SE, Wu Q, Lamba P, Sif S, Imbalzano AN. Promoter-enhancer looping at the PPAR?2 locus during adipogenic differentiation requires the Prmt5 methyltransferase. Nucleic Acids Res. 2016 06 20; 44(11):5133-47.
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Arriagada G, Henriquez B, Moena D, Merino P, Ruiz-Tagle C, Lian JB, Stein GS, Stein JL, Montecino M. Recruitment and subnuclear distribution of the regulatory machinery during 1alpha,25-dihydroxy vitamin D3-mediated transcriptional upregulation in osteoblasts. J Steroid Biochem Mol Biol. 2010 Jul; 121(1-2):156-8.
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Arriagada G, Paredes R, van Wijnen AJ, Lian JB, van Zundert B, Stein GS, Stein JL, Montecino M. 1alpha,25-dihydroxy vitamin D(3) induces nuclear matrix association of the 1alpha,25-dihydroxy vitamin D(3) receptor in osteoblasts independently of its ability to bind DNA. J Cell Physiol. 2010 Feb; 222(2):336-46.
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Carvallo L, Henr?quez B, Paredes R, Olate J, Onate S, van Wijnen AJ, Lian JB, Stein GS, Stein JL, Montecino M. 1alpha,25-dihydroxy vitamin D3-enhanced expression of the osteocalcin gene involves increased promoter occupancy of basal transcription regulators and gradual recruitment of the 1alpha,25-dihydroxy vitamin D3 receptor-SRC-1 coactivator complex. J Cell Physiol. 2008 Mar; 214(3):740-9.
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Sastre M, Klockgether T, Heneka MT. Contribution of inflammatory processes to Alzheimer's disease: molecular mechanisms. Int J Dev Neurosci. 2006 Apr-May; 24(2-3):167-76.