Capsid

"Capsid" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

The outer protein protective shell of a virus, which protects the viral nucleic acid.

Descriptor ID	D002213
MeSH Number(s)	A21.249.500.250 B04.950.500.250
Concept/Terms	Capsid Capsid Capsids

Below are MeSH descriptors whose meaning is more general than "Capsid".

Anatomy [A]
Viral Structures [A21]
Virion [A21.249]
Nucleocapsid [A21.249.500]
Capsid [A21.249.500.250]
Organisms [B]
Viruses [B04]
Virion [B04.950]
Nucleocapsid [B04.950.500]
Capsid [B04.950.500.250]

Below are MeSH descriptors whose meaning is related to "Capsid".

Below are MeSH descriptors whose meaning is more specific than "Capsid".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Capsid" by people in this website by year, and whether "Capsid" was a major or minor topic of these publications.

Bar chart showing 64 publications over 27 distinct years, with a maximum of 5 publications in 2012 and 2024 and 2025

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1996	2	0	2
1997	0	1	1
1998	1	0	1
1999	1	0	1
2000	2	1	3
2001	1	0	1
2002	2	1	3
2003	0	1	1
2004	0	2	2
2005	0	3	3
2006	1	1	2
2007	1	0	1
2008	0	2	2
2009	1	1	2
2011	1	1	2
2012	3	2	5
2013	2	1	3
2014	1	0	1
2015	2	0	2
2016	1	0	1
2017	2	1	3
2019	3	1	4
2020	3	1	4
2022	0	1	1
2023	0	3	3
2024	3	2	5
2025	5	0	5

Below are the most recent publications written about "Capsid" by people in Profiles.

Hoyle B, Hill J, Bello D. Quantifying the Full-to-Empty Adeno-Associated Virus (AAV) Capsid Ratios and Their Impact on Transduction Efficiency in vitro. AAPS J. 2025 Dec 17; 28(1):36.

View in: PubMed
Bal V, Wolfrum JM, Barone PW, Springs SL, Sinskey AJ, Kotin RM, Braatz RD. Selective Enrichment of Full Capsids of Adeno-Associated Virus. ACS Nano. 2025 Oct 14; 19(40):35348-35369.

View in: PubMed
Xing R, Xu M, Reil D, Destefano A, Cui M, Liu N, Liang J, Xu G, Luo L, Xu M, Zhang F, Tai PWL, Wei Y, Gruntman AM, Flotte TR, Gao G, Wang D. A single amino acid variant in the variable region I of AAV capsid confers liver detargeting. PLoS Pathog. 2025 Sep; 21(9):e1013533.

View in: PubMed
Roddy K, Grzesik P, Smith BJ, Ko N, Vashee S, Desai PJ. The loss of both pUL16 and pUL21 in HSV-1-infected cells alters capsid-tegument composition, nuclear membrane architecture, cytoplasmic maturation and cell-to-cell spread. J Gen Virol. 2025 03; 106(3).

View in: PubMed
M'Angale PG, Lemieux A, Liu Y, Wang S, Zinter M, Alegre G, Simkin A, Budnik V, Kelch BA, Thomson T. Capsid transfer of the retrotransposon Copia controls structural synaptic plasticity in Drosophila. PLoS Biol. 2025 Feb; 23(2):e3002983.

View in: PubMed
Furusho T, Das R, Hakui H, Sairavi A, Adachi K, Galbraith-Liss MS, Rajagopal P, Horikawa M, Luo S, Li L, Yamada K, Andeen N, Dissen GA, Nakai H. Enhancing gene transfer to renal tubules and podocytes by context-dependent selection of AAV capsids. Nat Commun. 2024 12 30; 15(1):10728.

View in: PubMed
Padron A, Dwivedi R, Chakraborty R, Prakash P, Kim K, Shi J, Ahn J, Pandhare J, Luban J, Aiken C, Balasubramaniam M, Dash C. Cyclophilin A facilitates HIV-1 integration. J Virol. 2024 11 19; 98(11):e0094724.

View in: PubMed
Fu Q, Wang Y, Qin J, Xie D, McNally D, Yoon S. Enhanced ER protein processing gene expression increases rAAV yield and full capsid ratio in HEK293 cells. Appl Microbiol Biotechnol. 2024 Sep 04; 108(1):459.

View in: PubMed
Cui M, Su Q, Yip M, McGowan J, Punzo C, Gao G, Tai PWL. The AAV2.7m8 capsid packages a higher degree of heterogeneous vector genomes than AAV2. Gene Ther. 2024 09; 31(9-10):489-498.

View in: PubMed
Suk Lee Y, Lee J, Fang K, Gee GV, Rogers B, McNally D, Yoon S. Separation of full, empty, and partial adeno-associated virus capsids via anion-exchange chromatography with continuous recycling and accumulation. J Chromatogr B Analyt Technol Biomed Life Sci. 2024 Jul 15; 1242:124206.

View in: PubMed

People

Explore

Similar Concepts

Top Journals