"Defective Viruses" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Viruses which lack a complete genome so that they cannot completely replicate or cannot form a protein coat. Some are host-dependent defectives, meaning they can replicate only in cell systems which provide the particular genetic function which they lack. Others, called SATELLITE VIRUSES, are able to replicate only when their genetic defect is complemented by a helper virus.
Descriptor ID |
D003673
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MeSH Number(s) |
B04.265
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Concept/Terms |
Defective Viruses- Defective Viruses
- Defective Virus
- Virus, Defective
- Viruses, Defective
- Defective Interfering Particles
- Defective Interfering Particle
- Interfering Particle, Defective
- Interfering Particles, Defective
- Particle, Defective Interfering
- Particles, Defective Interfering
- Incomplete Viruses
- Incomplete Virus
- Virus, Incomplete
- Viruses, Incomplete
- Defective Hybrids
- Defective Hybrid
- Hybrid, Defective
- Hybrids, Defective
- Defective Interfering Viruses
- Defective Interfering Virus
- Interfering Virus, Defective
- Interfering Viruses, Defective
- Virus, Defective Interfering
- Viruses, Defective Interfering
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Below are MeSH descriptors whose meaning is more general than "Defective Viruses".
Below are MeSH descriptors whose meaning is more specific than "Defective Viruses".
This graph shows the total number of publications written about "Defective Viruses" by people in this website by year, and whether "Defective Viruses" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
Year | Major Topic | Minor Topic | Total |
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1999 | 0 | 1 | 1 |
2018 | 0 | 1 | 1 |
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Below are the most recent publications written about "Defective Viruses" by people in Profiles.
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Sharaf R, Lee GQ, Sun X, Etemad B, Aboukhater LM, Hu Z, Brumme ZL, Aga E, Bosch RJ, Wen Y, Namazi G, Gao C, Acosta EP, Gandhi RT, Jacobson JM, Skiest D, Margolis DM, Mitsuyasu R, Volberding P, Connick E, Kuritzkes DR, Lederman MM, Yu XG, Lichterfeld M, Li JZ. HIV-1 proviral landscapes distinguish posttreatment controllers from noncontrollers. J Clin Invest. 2018 08 31; 128(9):4074-4085.
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Le Meur G, Weber M, P?r?on Y, Mendes-Madeira A, Nivard D, Deschamps JY, Moullier P, Rolling F. Postsurgical assessment and long-term safety of recombinant adeno-associated virus-mediated gene transfer into the retinas of dogs and primates. Arch Ophthalmol. 2005 Apr; 123(4):500-6.
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Weber M, Rabinowitz J, Provost N, Conrath H, Folliot S, Briot D, Ch?rel Y, Chenuaud P, Samulski J, Moullier P, Rolling F. Recombinant adeno-associated virus serotype 4 mediates unique and exclusive long-term transduction of retinal pigmented epithelium in rat, dog, and nonhuman primate after subretinal delivery. Mol Ther. 2003 Jun; 7(6):774-81.
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Favre D, Provost N, Blouin V, Blancho G, Ch?rel Y, Salvetti A, Moullier P. Immediate and long-term safety of recombinant adeno-associated virus injection into the nonhuman primate muscle. Mol Ther. 2001 Dec; 4(6):559-66.
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Flotte TR. Gene therapy for cystic fibrosis. Curr Opin Mol Ther. 1999 Aug; 1(4):510-6.
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Loiler SA, DiFronzo NL, Holland CA. Gene transfer to human cells using retrovirus vectors produced by a new polytropic packaging cell line. J Virol. 1997 Jun; 71(6):4825-8.
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Brubaker JO, Thompson CM, Morrison LA, Knipe DM, Siber GR, Finberg RW. Th1-associated immune responses to beta-galactosidase expressed by a replication-defective herpes simplex virus. J Immunol. 1996 Aug 15; 157(4):1598-604.
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Budenz DL, Bennett J, Alonso L, Maguire A. In vivo gene transfer into murine corneal endothelial and trabecular meshwork cells. Invest Ophthalmol Vis Sci. 1995 Oct; 36(11):2211-5.
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Moullier P, Friedlander G, Calise D, Ronco P, Perricaudet M, Ferry N. Adenoviral-mediated gene transfer to renal tubular cells in vivo. Kidney Int. 1994 Apr; 45(4):1220-5.
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Desrosiers RC, Silva DP, Waldron LM, Letvin NL. Nononcogenic deletion mutants of herpesvirus saimiri are defective for in vitro immortalization. J Virol. 1986 Feb; 57(2):701-5.