 Clusterin
"Clusterin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A highly conserved heterodimeric glycoprotein that is differentially expressed during many severe physiological disturbance states such as CANCER; APOPTOSIS; and various NEUROLOGICAL DISORDERS. Clusterin is ubiquitously expressed and appears to function as a secreted MOLECULAR CHAPERONE.
| Descriptor ID |
D051152
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| MeSH Number(s) |
D12.776.395.207 D12.776.580.215
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| Concept/Terms |
Clusterin- Clusterin
- XIP8 Protein
- Complement Lysis Inhibitor
- Complement-Associated Protein SP-40,40
- Complement Associated Protein SP 40,40
- SP-40,40, Complement-Associated Protein
- Ionizing Radiation-Induced Protein-8
- Ionizing Radiation Induced Protein 8
- Radiation-Induced Protein-8, Ionizing
- MAC393 Antigen
- SGP-2 Protein
- SGP 2 Protein
- SP 40,40 Protein
- 40,40 Protein, SP
- Sulfated Glycoprotein 2
- Sulfated Glycoprotein-2
- Testosterone-Repressed Prostate Message-2 Protein
- Testosterone Repressed Prostate Message 2 Protein
- TRPM-2 Protein
- TRPM 2 Protein
- X-Ray-Inducible Protein 8
- X Ray Inducible Protein 8
- ApoJ Protein
- Apolipoprotein J
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Below are MeSH descriptors whose meaning is more general than "Clusterin".
Below are MeSH descriptors whose meaning is more specific than "Clusterin".
This graph shows the total number of publications written about "Clusterin" by people in this website by year, and whether "Clusterin" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2007 | 0 | 1 | 1 | | 2010 | 1 | 0 | 1 | | 2011 | 0 | 1 | 1 | | 2013 | 1 | 0 | 1 |
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Below are the most recent publications written about "Clusterin" by people in Profiles.
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Shafie IN, McLaughlin M, Burchmore R, Lim MA, Montague P, Johnston PE, Penderis J, Anderson TJ. The chaperone protein clusterin may serve as a cerebrospinal fluid biomarker for chronic spinal cord disorders in the dog. Cell Stress Chaperones. 2014 May; 19(3):311-20.
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Miller DD, Emley A, Yang S, Richards JE, Lee JE, Deng A, Hoang MP, Mahalingam M. Mixed versus pure variants of desmoplastic melanoma: a genetic and immunohistochemical appraisal. Mod Pathol. 2012 Apr; 25(4):505-15.
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Golenkina SA, Gol'tsov AIu, Kuznetsova IL, Grigorenko AP, Andreeva TV, Reshetov DA, Kunizheva SS, Shagam LI, Morozova IIu, Goldenkova-Pavlova IV, Shimshilashvili Kh, Viacheslavova AO, Faskhutdinova G, Gareeva AÉ, Zainullina AG, Khusnutdinova ÉK, Puzyrev VP, Stepanov VA, Kolotvin AV, Samokhodskaia LM, Selezneva ND, Gavrilova SI, Rogaev EI. [Analysis of clusterin gene (CLU/APOJ) polymorphism in Alzheimer's disease patients and in normal cohorts from Russian populations]. Mol Biol (Mosk). 2010 Jul-Aug; 44(4):620-6.
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Somera-Molina KC, Robin B, Somera CA, Anderson C, Stine C, Koh S, Behanna HA, Van Eldik LJ, Watterson DM, Wainwright MS. Glial activation links early-life seizures and long-term neurologic dysfunction: evidence using a small molecule inhibitor of proinflammatory cytokine upregulation. Epilepsia. 2007 Sep; 48(9):1785-800.
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Ho SM, Leav I, Ghatak S, Merk F, Jagannathan VS, Mallery K. Lack of association between enhanced TRPM-2/clusterin expression and increased apoptotic activity in sex-hormone-induced prostatic dysplasia of the Noble rat. Am J Pathol. 1998 Jul; 153(1):131-9.
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