 HMGB1 Protein
"HMGB1 Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A 24-kDa HMGB protein that binds to and distorts the minor grove of DNA.
| Descriptor ID |
D024243
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| MeSH Number(s) |
D12.776.260.356.300 D12.776.660.235.400.600.300 D12.776.664.235.400.600.300
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| Concept/Terms |
HMGB1 Protein- HMGB1 Protein
- Box Protein 1, High Mobility Group
- FM1 Gene Product
- HMGB1
- HMG 1 Protein
- HMG-1 Protein
- HMG1
- Amphoterin
- Heparin-Binding Protein p30
- Heparin Binding Protein p30
- p30, Heparin-Binding Protein
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Below are MeSH descriptors whose meaning is more general than "HMGB1 Protein".
Below are MeSH descriptors whose meaning is more specific than "HMGB1 Protein".
This graph shows the total number of publications written about "HMGB1 Protein" by people in this website by year, and whether "HMGB1 Protein" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2006 | 2 | 0 | 2 | | 2007 | 1 | 1 | 2 | | 2010 | 1 | 0 | 1 | | 2013 | 0 | 1 | 1 | | 2015 | 1 | 1 | 2 |
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Below are the most recent publications written about "HMGB1 Protein" by people in Profiles.
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Lovely GA, Brewster RC, Schatz DG, Baltimore D, Phillips R. Single-molecule analysis of RAG-mediated V(D)J DNA cleavage. Proc Natl Acad Sci U S A. 2015 Apr 7; 112(14):E1715-23.
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Yang H, Wang H, Ju Z, Ragab AA, Lundbäck P, Long W, Valdes-Ferrer SI, He M, Pribis JP, Li J, Lu B, Gero D, Szabo C, Antoine DJ, Harris HE, Golenbock DT, Meng J, Roth J, Chavan SS, Andersson U, Billiar TR, Tracey KJ, Al-Abed Y. MD-2 is required for disulfide HMGB1-dependent TLR4 signaling. J Exp Med. 2015 Jan 12; 212(1):5-14.
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Lippai D, Bala S, Petrasek J, Csak T, Levin I, Kurt-Jones EA, Szabo G. Alcohol-induced IL-1ß in the brain is mediated by NLRP3/ASC inflammasome activation that amplifies neuroinflammation. J Leukoc Biol. 2013 Jul; 94(1):171-82.
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Avalos AM, Kiefer K, Tian J, Christensen S, Shlomchik M, Coyle AJ, Marshak-Rothstein A. RAGE-independent autoreactive B cell activation in response to chromatin and HMGB1/DNA immune complexes. Autoimmunity. 2010 Feb; 43(1):103-10.
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Kim CH, Han SI, Lee SY, Youk HS, Moon JY, Duong HQ, Park MJ, Joo YM, Park HG, Kim YJ, Yoo MA, Lim SC, Kang HS. Protein kinase C-ERK1/2 signal pathway switches glucose depletion-induced necrosis to apoptosis by regulating superoxide dismutases and suppressing reactive oxygen species production in A549 lung cancer cells. J Cell Physiol. 2007 May; 211(2):371-85.
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Tian J, Avalos AM, Mao SY, Chen B, Senthil K, Wu H, Parroche P, Drabic S, Golenbock D, Sirois C, Hua J, An LL, Audoly L, La Rosa G, Bierhaus A, Naworth P, Marshak-Rothstein A, Crow MK, Fitzgerald KA, Latz E, Kiener PA, Coyle AJ. Toll-like receptor 9-dependent activation by DNA-containing immune complexes is mediated by HMGB1 and RAGE. Nat Immunol. 2007 May; 8(5):487-96.
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Popovic PJ, DeMarco R, Lotze MT, Winikoff SE, Bartlett DL, Krieg AM, Guo ZS, Brown CK, Tracey KJ, Zeh HJ. High mobility group B1 protein suppresses the human plasmacytoid dendritic cell response to TLR9 agonists. J Immunol. 2006 Dec 15; 177(12):8701-7.
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Yu M, Wang H, Ding A, Golenbock DT, Latz E, Czura CJ, Fenton MJ, Tracey KJ, Yang H. HMGB1 signals through toll-like receptor (TLR) 4 and TLR2. Shock. 2006 Aug; 26(2):174-9.
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Chou DK, Zhang J, Smith FI, McCaffery P, Jungalwala FB. Developmental expression of receptor for advanced glycation end products (RAGE), amphoterin and sulfoglucuronyl (HNK-1) carbohydrate in mouse cerebellum and their role in neurite outgrowth and cell migration. J Neurochem. 2004 Sep; 90(6):1389-401.
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