Transient Receptor Potential Channels
"Transient Receptor Potential Channels" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A broad group of eukaryotic six-transmembrane cation channels that are classified by sequence homology because their functional involvement with SENSATION is varied. They have only weak voltage sensitivity and ion selectivity. They are named after a DROSOPHILA mutant that displayed transient receptor potentials in response to light. A 25-amino-acid motif containing a TRP box (EWKFAR) just C-terminal to S6 is found in TRPC, TRPV and TRPM subgroups. ANKYRIN REPEATS are found in TRPC, TRPV & TRPN subgroups. Some are functionally associated with TYROSINE KINASE or TYPE C PHOSPHOLIPASES.
| Descriptor ID |
D050051
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| MeSH Number(s) |
D12.776.157.530.400.901 D12.776.543.585.400.901
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| Concept/Terms |
Transient Receptor Potential Channels- Transient Receptor Potential Channels
- TRP Membrane Proteins
- Membrane Proteins, TRP
- Proteins, TRP Membrane
- TRP Cation Channels
- Cation Channels, TRP
- Channels, TRP Cation
- Transient Receptor Potential Cation Channels
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Below are MeSH descriptors whose meaning is more general than "Transient Receptor Potential Channels".
Below are MeSH descriptors whose meaning is more specific than "Transient Receptor Potential Channels".
This graph shows the total number of publications written about "Transient Receptor Potential Channels" by people in this website by year, and whether "Transient Receptor Potential Channels" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2012 | 1 | 0 | 1 |
| 2023 | 1 | 0 | 1 |
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Below are the most recent publications written about "Transient Receptor Potential Channels" by people in Profiles.
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Mukhopadhyay D, Goel HL, Xiong C, Goel S, Kumar A, Li R, Zhu LJ, Clark JL, Brehm MA, Mercurio AM. The calcium channel TRPC6 promotes chemotherapy-induced persistence by regulating integrin a6 mRNA splicing. Cell Rep. 2023 11 28; 42(11):113347.
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Ma Z, Freeman MR. TrpML-mediated astrocyte microdomain Ca2+ transients regulate astrocyte-tracheal interactions. Elife. 2020 12 07; 9.
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Ma Z, Stork T, Bergles DE, Freeman MR. Neuromodulators signal through astrocytes to alter neural circuit activity and behaviour. Nature. 2016 11 17; 539(7629):428-432.
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Yan Z, Zhang W, He Y, Gorczyca D, Xiang Y, Cheng LE, Meltzer S, Jan LY, Jan YN. Drosophila NOMPC is a mechanotransduction channel subunit for gentle-touch sensation. Nature. 2013 Jan 10; 493(7431):221-5.
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Yonamine I, Bamba T, Nirala NK, Jesmin N, Kosakowska-Cholody T, Nagashima K, Fukusaki E, Acharya JK, Acharya U. Sphingosine kinases and their metabolites modulate endolysosomal trafficking in photoreceptors. J Cell Biol. 2011 Feb 21; 192(4):557-67.
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Xu XZ, Li HS, Guggino WB, Montell C. Coassembly of TRP and TRPL produces a distinct store-operated conductance. Cell. 1997 Jun 27; 89(7):1155-64.