Tumor Suppressor Proteins

"Tumor Suppressor Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Proteins that are normally involved in holding cellular growth in check. Deficiencies or abnormalities in these proteins may lead to unregulated cell growth and tumor development.

Descriptor ID	D025521
MeSH Number(s)	D12.776.624.776
Concept/Terms	Tumor Suppressor Proteins Tumor Suppressor Proteins Proteins, Tumor Suppressor Metastasis Suppressor Proteins Metastasis Suppressor Proteins Proteins, Metastasis Suppressor Growth Suppressor Proteins Growth Suppressor Proteins Proteins, Growth Suppressor

Below are MeSH descriptors whose meaning is more general than "Tumor Suppressor Proteins".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Neoplasm Proteins [D12.776.624]
Tumor Suppressor Proteins [D12.776.624.776]

Below are MeSH descriptors whose meaning is related to "Tumor Suppressor Proteins".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Tumor Suppressor Proteins" by people in this website by year, and whether "Tumor Suppressor Proteins" was a major or minor topic of these publications.

Bar chart showing 166 publications over 30 distinct years, with a maximum of 11 publications in 2010 and 2011

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1995	0	1	1
1996	0	1	1
1997	2	0	2
1998	1	0	1
1999	1	1	2
2000	1	3	4
2001	2	1	3
2002	7	2	9
2003	5	4	9
2004	2	6	8
2005	2	4	6
2006	4	4	8
2007	4	1	5
2008	5	4	9
2009	3	3	6
2010	5	6	11
2011	8	3	11
2012	3	5	8
2013	3	5	8
2014	4	5	9
2015	5	5	10
2016	4	3	7
2017	0	1	1
2018	4	3	7
2019	5	2	7
2020	1	2	3
2021	2	4	6
2023	0	1	1
2024	0	2	2
2025	1	0	1

Below are the most recent publications written about "Tumor Suppressor Proteins" by people in Profiles.

Abou Nader N, Jakuc N, Meinsohn MC, Charrier L, Banville L, Brind'Amour J, Paquet M, St-Jean G, Boerboom D, Mao J, P?pin D, Breault DT, Zamberlam G, Boyer A. Hippo Signaling Is Essential for the Maintenance of Zona Glomerulosa Cell Fate in the Murine Adrenal Cortex. Endocrinology. 2025 Apr 22; 166(6).

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Lee WP, Choi SH, Shea MG, Cheng PL, Dombroski BA, Pitsillides AN, Heard-Costa NL, Wang H, Bulekova K, Kuzma AB, Leung YY, Farrell JJ, Lin H, Kunkle BW, Naj A, Blue EE, Nusetor F, Wang D, Boerwinkle E, Bush WS, Zhang X, De Jager PL, Dupuis J, Farrer LA, Fornage M, Martin E, Pericak-Vance M, Seshadri S, Wijsman EM, Wang LS, Schellenberg GD, Destefano AL, Haines JL, Peloso GM. Association of common and rare variants with Alzheimer's disease in more than 13,000 diverse individuals with whole-genome sequencing from the Alzheimer's Disease Sequencing Project. Alzheimers Dement. 2024 Dec; 20(12):8470-8483.

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Ray S, DeSilva C, Dasgupta I, Mana-Capelli S, Cruz-Calderon N, McCollum D. The ability of the LIMD1 and TRIP6 LIM domains to bind strained f-actin is critical for their tension dependent localization to adherens junctions and association with the Hippo pathway kinase LATS1. Cytoskeleton (Hoboken). 2024 Sep; 81(9-10):436-447.

View in: PubMed
Medeiros MC, The S, Bellile E, Russo N, Schmitd L, Danella E, Singh P, Banerjee R, Bassis C, Murphy GR, Sartor MA, Lombaert I, Schmidt TM, Eisbruch A, Murdoch-Kinch CA, Rozek L, Wolf GT, Li G, Chen GY, D'Silva NJ. Salivary microbiome changes distinguish response to chemoradiotherapy in patients with oral cancer. Microbiome. 2023 Nov 30; 11(1):268.

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Liu S, Bellile E, Nguyen A, Zarins K, D'Silva N, Rozek L, Wolf GT, Sartor MA. Characterization of the immune response in patients with cancer of the oral cavity after neoadjuvant immunotherapy with the IRX-2 regimen. Oral Oncol. 2021 12; 123:105587.

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Lv B, Stuck MW, Desai PB, Cabrera OA, Pazour GJ. E3 ubiquitin ligase Wwp1 regulates ciliary dynamics of the Hedgehog receptor Smoothened. J Cell Biol. 2021 09 06; 220(9).

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Carter P, Schnell U, Chaney C, Tong B, Pan X, Ye J, Mernaugh G, Cotton JL, Margulis V, Mao J, Zent R, Evers BM, Kapur P, Carroll TJ. Deletion of Lats1/2 in adult kidney epithelia leads to renal cell carcinoma. J Clin Invest. 2021 06 01; 131(11).

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Huang WY, Wen LH, Wu G, Pang PP, Ogbuji R, Zhang CC, Chen F, Zhao JN. Radiological model based on the standard magnetic resonance sequences for detecting methylguanine methyltransferase methylation in glioma using texture analysis. Cancer Sci. 2021 Jul; 112(7):2835-2844.

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Politi LS, Pessina F, Simonelli M, Navarria P. Editorial for "Noninvasive Assessment of MGMT Promoter Methylation Status in World Health Organization Grade II-IV Glioma Using Histogram Analysis of Inflow-Based Vascular-Space Occupancy Combined with Structural MR Imaging". J Magn Reson Imaging. 2021 07; 54(1):237-238.

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Maor-Nof M, Shipony Z, Lopez-Gonzalez R, Nakayama L, Zhang YJ, Couthouis J, Blum JA, Castruita PA, Linares GR, Ruan K, Ramaswami G, Simon DJ, Nof A, Santana M, Han K, Sinnott-Armstrong N, Bassik MC, Geschwind DH, Tessier-Lavigne M, Attardi LD, Lloyd TE, Ichida JK, Gao FB, Greenleaf WJ, Yokoyama JS, Petrucelli L, Gitler AD. p53 is a central regulator driving neurodegeneration caused by C9orf72 poly(PR). Cell. 2021 02 04; 184(3):689-708.e20.

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