"Kynurenine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A metabolite of the essential amino acid tryptophan metabolized via the tryptophan-kynurenine pathway.
Descriptor ID |
D007737
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MeSH Number(s) |
D12.125.608
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Kynurenine".
Below are MeSH descriptors whose meaning is more specific than "Kynurenine".
This graph shows the total number of publications written about "Kynurenine" by people in this website by year, and whether "Kynurenine" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2014 | 1 | 0 | 1 |
2016 | 2 | 0 | 2 |
2017 | 1 | 0 | 1 |
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Below are the most recent publications written about "Kynurenine" by people in Profiles.
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Malhotra R, Persic V, Zhang W, Brown J, Tao X, Rosales L, Thijssen S, Finkelstein FO, Unruh ML, Ikizler A, Garimella PS, Ix JH, Kooman J, Levin NW, Handelman GJ, Kotanko P. Tryptophan and Kynurenine Levels and Its Association With Sleep, Nonphysical Fatigue, and Depression in Chronic Hemodialysis Patients. J Ren Nutr. 2017 07; 27(4):260-266.
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Mudry JM, Alm PS, Erhardt S, Goiny M, Fritz T, Caidahl K, Zierath JR, Krook A, Wallberg-Henriksson H. Direct effects of exercise on kynurenine metabolism in people with normal glucose tolerance or type 2 diabetes. Diabetes Metab Res Rev. 2016 10; 32(7):754-761.
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Lu H, Yu J, Wang J, Wu L, Xiao H, Gao R. Simultaneous quantification of neuroactive dopamine serotonin and kynurenine pathway metabolites in gender-specific youth urine by ultra performance liquid chromatography tandem high resolution mass spectrometry. J Pharm Biomed Anal. 2016 Apr 15; 122:42-51.
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Agudelo LZ, Femen?a T, Orhan F, Porsmyr-Palmertz M, Goiny M, Martinez-Redondo V, Correia JC, Izadi M, Bhat M, Schuppe-Koistinen I, Pettersson AT, Ferreira DMS, Krook A, Barres R, Zierath JR, Erhardt S, Lindskog M, Ruas JL. Skeletal muscle PGC-1a1 modulates kynurenine metabolism and mediates resilience to stress-induced depression. Cell. 2014 Sep 25; 159(1):33-45.
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Outinen TK, M?kel? SM, Ala-Houhala IO, Huhtala HS, Hurme M, Libraty DH, Oja SS, P?rsti IH, Syrj?nen JT, Vaheri A, Mustonen JT. High activity of indoleamine 2,3-dioxygenase is associated with renal insufficiency in Puumala hantavirus induced nephropathia epidemica. J Med Virol. 2011 Apr; 83(4):731-7.
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Wang Y, Liu H, McKenzie G, Witting PK, Stasch JP, Hahn M, Changsirivathanathamrong D, Wu BJ, Ball HJ, Thomas SR, Kapoor V, Celermajer DS, Mellor AL, Keaney JF, Hunt NH, Stocker R. Kynurenine is an endothelium-derived relaxing factor produced during inflammation. Nat Med. 2010 Mar; 16(3):279-85.