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Last Name

Alisha M Gruntman DVM, PhD

TitleAssistant Professor
InstitutionUniversity of Massachusetts Medical School
AddressUniversity of Massachusetts Medical School
55 Lake Ave North
Worcester MA 01605
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    Other Positions
    InstitutionUMMS - School of Medicine

    Collapse Biography 
    Collapse education and training
    Purdue University West Lafayette, West Lafayette, IN, United StatesDVMVeterinary Medicine
    University of Massachusetts Medical School, Worcester, MA, United StatesPHDGene Therapy

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Borel F, Sun H, Zieger M, Cox A, Cardozo B, Li W, Oliveira G, Davis A, Gruntman A, Flotte TR, Brodsky MH, Hoffman AM, Elmallah MK, Mueller C. Editing out five Serpina1 paralogs to create a mouse model of genetic emphysema. Proc Natl Acad Sci U S A. 2018 Mar 13; 115(11):2788-2793. PMID: 29453277.
      View in: PubMed
    2. Mueller C, Gernoux G, Gruntman AM, Borel F, Reeves EP, Calcedo R, Rouhani FN, Yachnis A, Humphries M, Campbell-Thompson M, Messina L, Chulay JD, Trapnell B, Wilson JM, McElvaney NG, Flotte TR. 5 Year Expression and Neutrophil Defect Repair after Gene Therapy in Alpha-1 Antitrypsin Deficiency. Mol Ther. 2017 Apr 10. PMID: 28408179.
      View in: PubMed
    3. Gruntman AM, Su L, Flotte TR. Retro-Orbital Venous Sinus Delivery of rAAV9 Mediates High-Level Transduction of Brain and Retina Compared with Temporal Vein Delivery in Neonatal Mouse Pups. Hum Gene Ther. 2017 Mar; 28(3):228-230. PMID: 28319444.
      View in: PubMed
    4. Gruntman AM. Genotyping Protocol for the Alpha-1 Antitrypsin (PiZ) Mouse Model. Methods Mol Biol. 2017; 1639:61-65. PMID: 28752446.
      View in: PubMed
    5. Gruntman AM, Flotte TR. Therapeutics: Gene Therapy for Alpha-1 Antitrypsin Deficiency. Methods Mol Biol. 2017; 1639:267-275. PMID: 28752467.
      View in: PubMed
    6. Tang Q, Gruntman AM, Flotte TR. Quantification of Total Human Alpha-1 Antitrypsin by Sandwich ELISA. Methods Mol Biol. 2017; 1639:211-216. PMID: 28752460.
      View in: PubMed
    7. Gruntman AM, Flotte TR. Delivery of Adeno-Associated Virus Gene Therapy by Intravascular Limb Infusion Methods. Hum Gene Ther Clin Dev. 2015 Sep; 26(3):159-64. PMID: 26357010.
      View in: PubMed
    8. Gruntman AM, Flotte TR. Progress with Recombinant Adeno-Associated Virus Vectors for Gene Therapy of Alpha-1 Antitrypsin Deficiency. Hum Gene Ther Methods. 2015 Jun; 26(3):77-81. PMID: 26067712.
      View in: PubMed
    9. Gruntman AM, Su L, Su Q, Gao G, Mueller C, Flotte TR. Stability and compatibility of recombinant adeno-associated virus under conditions commonly encountered in human gene therapy trials. Hum Gene Ther Methods. 2015 Apr; 26(2):71-6. PMID: 25819833.
      View in: PubMed
    10. Paxson JA, Gruntman AM, Davis AM, Parkin CM, Ingenito EP, Hoffman AM. Age dependence of lung mesenchymal stromal cell dynamics following pneumonectomy. Stem Cells Dev. 2013 Dec 15; 22(24):3214-25. PMID: 23895415; PMCID: PMC3868307.
    11. Gruntman AM, Bish LT, Mueller C, Sweeney HL, Flotte TR, Gao G. Gene transfer in skeletal and cardiac muscle using recombinant adeno-associated virus. Curr Protoc Microbiol. 2013; Chapter 14:Unit 14D.3. PMID: 23408131.
      View in: PubMed
    12. Gruntman AM, Mueller C, Flotte TR, Gao G. Gene transfer in the lung using recombinant adeno-associated virus. Curr Protoc Microbiol. 2012 Aug; Chapter 14:Unit14D.2. PMID: 22875566.
      View in: PubMed
    13. Mueller C, Tang Q, Gruntman A, Blomenkamp K, Teckman J, Song L, Zamore PD, Flotte TR. Sustained miRNA-mediated knockdown of mutant AAT with simultaneous augmentation of wild-type AAT has minimal effect on global liver miRNA profiles. Mol Ther. 2012 Mar; 20(3):590-600. PMID: 22252449.
      View in: PubMed
    14. Paxson JA, Gruntman A, Parkin CD, Mazan MR, Davis A, Ingenito EP, Hoffman AM. Age-dependent decline in mouse lung regeneration with loss of lung fibroblast clonogenicity and increased myofibroblastic differentiation. PLoS One. 2011; 6(8):e23232. PMID: 21912590; PMCID: PMC3166052.
    15. Melidone R, Parry NM, Gruntman A. Urinary bladder agenesis in an alpaca (Vicugna pacos) cria. J Vet Diagn Invest. 2010 May; 22(3):473-5. PMID: 20453232.
      View in: PubMed
    16. Hoffman AM, Shifren A, Mazan MR, Gruntman AM, Lascola KM, Nolen-Walston RD, Kim CF, Tsai L, Pierce RA, Mecham RP, Ingenito EP. Matrix modulation of compensatory lung regrowth and progenitor cell proliferation in mice. Am J Physiol Lung Cell Mol Physiol. 2010 Feb; 298(2):L158-68. PMID: 19915155; PMCID: PMC2822560.
    17. Gruntman A, Nolen-Walston R, Parry N, Wilborn R, Maxwell H. Presumptive albendazole toxicosis in 12 alpacas. J Vet Intern Med. 2009 Jul-Aug; 23(4):945-9. PMID: 19496913.
      View in: PubMed
    18. Nolen-Walston RD, Kim CF, Mazan MR, Ingenito EP, Gruntman AM, Tsai L, Boston R, Woolfenden AE, Jacks T, Hoffman AM. Cellular kinetics and modeling of bronchioalveolar stem cell response during lung regeneration. Am J Physiol Lung Cell Mol Physiol. 2008 Jun; 294(6):L1158-65. PMID: 18375744; PMCID: PMC2593913.
    19. Rosenthal FS, Gruntman A, Couetil LL. A comparison of total, respirable, and real-time airborne particulate sampling in horse barns. J Occup Environ Hyg. 2006 Nov; 3(11):599-605. PMID: 17086664.
      View in: PubMed
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