"Pyroptosis" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Type of programmed cell death associated with infection by intracellular pathogens. It is characterized by INFLAMMASOME formation; activation of CASPASE 1; and CYTOKINES mediated inflammation.
| Descriptor ID |
D000069292
|
| MeSH Number(s) |
G04.146.160.530
|
| Concept/Terms |
Pyroptosis- Pyroptosis
- Pyroptoses
- Pyroptotic Cell Death
- Cell Death, Pyroptotic
- Cell Deaths, Pyroptotic
- Death, Pyroptotic Cell
- Deaths, Pyroptotic Cell
- Pyroptotic Cell Deaths
- Inflammatory Apoptosis
- Apoptoses, Inflammatory
- Apoptosis, Inflammatory
- Inflammatory Apoptoses
- Caspase-1 Dependent Cell Death
- Caspase 1 Dependent Cell Death
|
Below are MeSH descriptors whose meaning is more general than "Pyroptosis".
Below are MeSH descriptors whose meaning is more specific than "Pyroptosis".
This graph shows the total number of publications written about "Pyroptosis" by people in this website by year, and whether "Pyroptosis" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2019 | 1 | 2 | 3 |
| 2020 | 2 | 2 | 4 |
| 2021 | 3 | 3 | 6 |
| 2023 | 0 | 2 | 2 |
| 2024 | 0 | 1 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Pyroptosis" by people in Profiles.
-
Stine L, Humphries F. Gasdermin D palmitoylation: to cleave or not to cleave? Trends Immunol. 2024 Jun; 45(6):403-405.
-
Orzalli MH. An orphan no more: Nur77 senses cytosolic LPS. Immunity. 2023 04 11; 56(4):742-744.
-
Humphries F. Biochemical Methods for Assessing Gasdermin D Inactivation in Macrophages. Methods Mol Biol. 2023; 2641:125-133.
-
Ketelut-Carneiro N, Fitzgerald KA. Apoptosis, Pyroptosis, and Necroptosis-Oh My! The Many Ways a Cell Can Die. J Mol Biol. 2022 02 28; 434(4):167378.
-
de Carvalho Ribeiro M, Szabo G. Role of the Inflammasome in Liver Disease. Annu Rev Pathol. 2022 01 24; 17:345-365.
-
Humphries F, Fitzgerald KA. Igniting the firestorm: The inflammasome in autoinflammatory syndromes. J Allergy Clin Immunol. 2021 12; 148(6):1470-1472.
-
Budden CF, Gearing LJ, Kaiser R, Standke L, Hertzog PJ, Latz E. Inflammasome-induced extracellular vesicles harbour distinct RNA signatures and alter bystander macrophage responses. J Extracell Vesicles. 2021 08; 10(10):e12127.
-
Orzalli MH, Prochera A, Payne L, Smith A, Garlick JA, Kagan JC. Virus-mediated inactivation of anti-apoptotic Bcl-2 family members promotes Gasdermin-E-dependent pyroptosis in barrier epithelial cells. Immunity. 2021 07 13; 54(7):1447-1462.e5.
-
Bertheloot D, Latz E, Franklin BS. Necroptosis, pyroptosis and apoptosis: an intricate game of cell death. Cell Mol Immunol. 2021 05; 18(5):1106-1121.
-
Tian Y, Qu S, Alam HB, Williams AM, Wu Z, Deng Q, Pan B, Zhou J, Liu B, Duan X, Ma J, Mondal S, Thompson PR, Stringer KA, Standiford TJ, Li Y. Peptidylarginine deiminase 2 has potential as both a biomarker and therapeutic target of sepsis. JCI Insight. 2020 10 15; 5(20).