PAX3 Transcription Factor
"PAX3 Transcription Factor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A paired box transcription factor that functions in CELL PROLIFERATION; CELL MIGRATION; and APOPTOSIS. It also is involved in MYOGENESIS and neural development. Mutations in the PAX3 gene are associated with WAARDENBURG SYNDROME TYPE 1.
Descriptor ID |
D000072041
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MeSH Number(s) |
D12.776.260.645.782 D12.776.930.700.782
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Concept/Terms |
PAX3 Transcription Factor- PAX3 Transcription Factor
- Transcription Factor, PAX3
- Paired Box Transcription Factor 3
- Transcription Factor PAX3
- Factor PAX3, Transcription
- PAX3, Transcription Factor
- Paired Box 3 Protein
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Below are MeSH descriptors whose meaning is more general than "PAX3 Transcription Factor".
Below are MeSH descriptors whose meaning is more specific than "PAX3 Transcription Factor".
This graph shows the total number of publications written about "PAX3 Transcription Factor" by people in this website by year, and whether "PAX3 Transcription Factor" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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1997 | 0 | 1 | 1 |
1999 | 0 | 1 | 1 |
2005 | 0 | 1 | 1 |
2011 | 0 | 1 | 1 |
2012 | 0 | 1 | 1 |
2013 | 0 | 1 | 1 |
2018 | 0 | 1 | 1 |
2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "PAX3 Transcription Factor" by people in Profiles.
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Guo D, Daman K, Chen JJ, Shi MJ, Yan J, Matijasevic Z, Rickard AM, Bennett MH, Kiselyov A, Zhou H, Bang AG, Wagner KR, Maehr R, King OD, Hayward LJ, Emerson CP. iMyoblasts for ex vivo and in vivo investigations of human myogenesis and disease modeling. Elife. 2022 01 25; 11.
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Orriss IR, Lanham S, Savery D, Greene NDE, Stanier P, Oreffo R, Copp AJ, Galea GL. Spina bifida-predisposing heterozygous mutations in Planar Cell Polarity genes and Zic2 reduce bone mass in young mice. Sci Rep. 2018 02 20; 8(1):3325.
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Himeda CL, Barro MV, Emerson CP. Pax3 synergizes with Gli2 and Zic1 in transactivating the Myf5 epaxial somite enhancer. Dev Biol. 2013 Nov 01; 383(1):7-14.
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Bonvin E, Falletta P, Shaw H, Delmas V, Goding CR. A phosphatidylinositol 3-kinase-Pax3 axis regulates Brn-2 expression in melanoma. Mol Cell Biol. 2012 Nov; 32(22):4674-83.
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Singh N, Trivedi CM, Lu M, Mullican SE, Lazar MA, Epstein JA. Histone deacetylase 3 regulates smooth muscle differentiation in neural crest cells and development of the cardiac outflow tract. Circ Res. 2011 Nov 11; 109(11):1240-9.
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Darabi R, Baik J, Clee M, Kyba M, Tupler R, Perlingeiro RC. Engraftment of embryonic stem cell-derived myogenic progenitors in a dominant model of muscular dystrophy. Exp Neurol. 2009 Nov; 220(1):212-6.
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Hanel ML, Wuebbles RD, Jones PL. Muscular dystrophy candidate gene FRG1 is critical for muscle development. Dev Dyn. 2009 Jun; 238(6):1502-12.
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Bradshaw L, Chaudhry B, Hildreth V, Webb S, Henderson DJ. Dual role for neural crest cells during outflow tract septation in the neural crest-deficient mutant Splotch(2H). J Anat. 2009 Feb; 214(2):245-57.
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Jensen AM. Potential roles for BMP and Pax genes in the development of iris smooth muscle. Dev Dyn. 2005 Feb; 232(2):385-92.
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Borycki AG, Li J, Jin F, Emerson CP, Epstein JA. Pax3 functions in cell survival and in pax7 regulation. Development. 1999 Apr; 126(8):1665-74.