Below are the most recent publications written about "Induced Pluripotent Stem Cells" by people in Profiles.
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Gontier G, Kim G, Wang C, Zhu K, Gau R, Zhang N, Naphade S, Stewart A, Schmidt MJ, Galemmo R, Shook B, Tarachandani A, Choi I, Raines S, Scannevin RH, Grievink HW, Smits LMG, Kremer PHC, Cadavid D. Glycoprotein Non-Metastatic Melanoma Protein B (GPNMB): A Translational Pharmacodynamic Biomarker for PIKfyve Inhibition With VRG50635. Clin Transl Sci. 2026 Feb; 19(2):e70489.
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Shah S, Barnes D, Liu B, Tseyang T, Do T, Bubenik JL, Jung S, Anadolu MN, Ivshina MP, Mart?nez-Cerde?o V, Berry-Kravis E, Swanson MS, Spinelli JB, Richter JD. Metabolic reprogramming during human neuron differentiation indicates glutaminase as a key determinant in Fragile X syndrome. Cell Rep. 2026 Jan 27; 45(1):116857.
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Jun YW, Lee S, Almeida S, Freude KK, Ichida JK, Gao FB. The Ku80-p53-SIRT1 axis in DNA damage response contributes to sporadic and familial ALS and FTD. Nat Commun. 2025 Dec 20; 17(1):1007.
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Tolomeo M, Magliocca V, Petrini S, Nisco A, Barbaro R, Lanza M, Piccione M, Giudetti AM, Massey K, Console L, Indiveri C, Zanier K, Bertini E, Persichini T, Compagnucci C, Colella M, Barile M. Altered dimerization of certain riboflavin transporter 2 mutants: a possible source of UPR, altered calcium signalling and mitochondrial derangements in RTD2. Arch Biochem Biophys. 2026 Jan; 775:110675.
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Joseph BJ, Marshall KA, Harley P, Mann JR, Alessandrini F, Vanoye CG, Chi W, Prudencio M, Simkin D, Kao TT, Desai RR, Keuss MJ, Barattucci S, Zanovello M, Mehta PR, DeKeyser JM, Limone F, Lee J, Brown AL, Leyton-Jaimes MF, Nash LA, Juan IGS, Aronica E, Wainger BJ, Shah M, Goswami A, Shneider NA, Dickson DW, Burrone J, Zhang C, Wichterle H, Petrucelli L, Watts JK, George AL, Fratta P, Eggan K, Kiskinis E. TDP-43-dependent mis-splicing of KCNQ2 triggers intrinsic neuronal hyperexcitability in ALS/FTD. Nat Neurosci. 2025 Dec; 28(12):2476-2492.
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Fang M, Banday S, Deibler SK, Simone TM, Coleman M, O'Connor E, Li R, Zhu LJ, Green MR. Inhibition of Rho-Associated Kinases ROCK1 and ROCK2 as a Therapeutic Strategy to Reactivate the Repressed FXN Gene in Friedreich Ataxia. J Neurosci. 2025 06 25; 45(26).
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Liu S, Li L, Zhang F, Garcia-Corral M, Meyer K, Fortuna PRJ, van Sambeek B, Appleton E, Ng AHM, Khoshakhlagh P, Lu YR, Cameron J, Ramirez RN, Chen Y, Wu CT, Huang JY, Tan Y, Chao G, Aach J, Lim ET, Tam JM, Raychaudhuri S, Church GM. Iterative transcription factor screening enables rapid generation of microglia-like cells from human iPSC. Nat Commun. 2025 Jun 10; 16(1):5136.
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Liu Z, Tan Y, Flynn WF, Sun L, Pratumkaew P, Alcoforado Diniz J, Oliveira NAJ, McDonough JA, Skarnes WC, Robson P. HAND1, partially mediated through ape-specific LTR binding, is essential for human extra-embryonic mesenchyme derivation from iPSCs. Cell Rep. 2025 Apr 22; 44(4):115568.
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Mon-Wei Yu S, Choi JY, Kady J, De Cos M, Wong JS, King E, Younis N, Al Rahy N, Al Chaar S, Djebli H, Eskandari S, Samuel S, Merhej T, Sukumar N, Lin JR, Chen JY, Xu Y, Santagata S, Weins A, Yeung M, Cravedi P, Campbell KN, Lemos D, Bonventre JV, Brehm MA, Azzi J. Transplantation of human kidney organoids elicited a robust allogeneic response in a humanized mouse model. Kidney Int. 2025 Jun; 107(6):1011-1016.
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Pierson Smela M, Kramme CC, Fortuna PRJ, Wolf B, Goel S, Adams J, Ma C, Velychko S, Widocki U, Srikar Kavirayuni V, Chen T, Vincoff S, Dong E, Kohman RE, Kobayashi M, Shioda T, Church GM, Chatterjee P. Rapid human oogonia-like cell specification via transcription factor-directed differentiation. EMBO Rep. 2025 Feb; 26(4):1114-1143.