Regulatory-Associated Protein of mTOR
"Regulatory-Associated Protein of mTOR" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An adaptor protein component of the MECHANISTIC TARGET OF RAPAMYCIN COMPLEX 1 that forms stoichiometric complexes with TOR KINASES, which it negatively regulates. It functions as a positive regulator of RIBOSOMAL PROTEIN S6 KINASES.
Descriptor ID |
D000076223
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MeSH Number(s) |
D05.500.337.500 D08.811.913.696.620.682.700.931.500.500 D12.644.360.024.324 D12.776.157.057.157 D12.776.476.024.419 D12.776.476.925.500.500
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Regulatory-Associated Protein of mTOR".
Below are MeSH descriptors whose meaning is more specific than "Regulatory-Associated Protein of mTOR".
This graph shows the total number of publications written about "Regulatory-Associated Protein of mTOR" by people in this website by year, and whether "Regulatory-Associated Protein of mTOR" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2012 | 0 | 1 | 1 |
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Below are the most recent publications written about "Regulatory-Associated Protein of mTOR" by people in Profiles.
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Miloslavski R, Cohen E, Avraham A, Iluz Y, Hayouka Z, Kasir J, Mudhasani R, Jones SN, Cybulski N, R?egg MA, Larsson O, Gandin V, Rajakumar A, Topisirovic I, Meyuhas O. Oxygen sufficiency controls TOP mRNA translation via the TSC-Rheb-mTOR pathway in a 4E-BP-independent manner. J Mol Cell Biol. 2014 Jun; 6(3):255-66.
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Kalaitzidis D, Sykes SM, Wang Z, Punt N, Tang Y, Ragu C, Sinha AU, Lane SW, Souza AL, Clish CB, Anastasiou D, Gilliland DG, Scadden DT, Guertin DA, Armstrong SA. mTOR complex 1 plays critical roles in hematopoiesis and Pten-loss-evoked leukemogenesis. Cell Stem Cell. 2012 Sep 07; 11(3):429-39.