Signaling Lymphocytic Activation Molecule Associated Protein
"Signaling Lymphocytic Activation Molecule Associated Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A signal transducing adaptor protein that contains a single SH2 DOMAIN and is essential for the regulation of SLAM FAMILY RECEPTORS in the immune response. Mutations in the SLAM-associated protein gene have been identified in cases of X-LINKED LYMPHOPROLIFERATIVE DISEASE.
| Descriptor ID |
D000071179
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| MeSH Number(s) |
D12.644.360.024.332 D12.776.157.057.166 D12.776.476.024.426
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Signaling Lymphocytic Activation Molecule Associated Protein".
Below are MeSH descriptors whose meaning is more specific than "Signaling Lymphocytic Activation Molecule Associated Protein".
This graph shows the total number of publications written about "Signaling Lymphocytic Activation Molecule Associated Protein" by people in this website by year, and whether "Signaling Lymphocytic Activation Molecule Associated Protein" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 0 | 1 | 1 |
| 2006 | 0 | 1 | 1 |
| 2008 | 0 | 1 | 1 |
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Below are the most recent publications written about "Signaling Lymphocytic Activation Molecule Associated Protein" by people in Profiles.
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Kamperschroer C, Roberts DM, Zhang Y, Weng NP, Swain SL. SAP enables T cells to help B cells by a mechanism distinct from Th cell programming or CD40 ligand regulation. J Immunol. 2008 Sep 15; 181(6):3994-4003.
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Kamperschroer C, Dibble JP, Meents DL, Schwartzberg PL, Swain SL. SAP is required for Th cell function and for immunity to influenza. J Immunol. 2006 Oct 15; 177(8):5317-27.
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Sullivan JL. The abnormal gene in X-linked lymphoproliferative syndrome. Curr Opin Immunol. 1999 Aug; 11(4):431-4.