RNA, Long Noncoding

"RNA, Long Noncoding" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A class of untranslated RNA molecules that are typically greater than 200 nucleotides in length and do not code for proteins. Members of this class have been found to play roles in transcriptional regulation, post-transcriptional processing, CHROMATIN REMODELING, and in the epigenetic control of chromatin.

Descriptor ID	D062085
MeSH Number(s)	D13.444.735.790.375
Concept/Terms	RNA, Long Noncoding RNA, Long Noncoding Noncoding RNA, Long lncRNA Long ncRNA ncRNA, Long RNA, Long Non-Translated Long Non-Translated RNA Non-Translated RNA, Long RNA, Long Non Translated Long Non-Coding RNA Long Non Coding RNA Non-Coding RNA, Long RNA, Long Non-Coding Long Non-Protein-Coding RNA Long Non Protein Coding RNA Non-Protein-Coding RNA, Long RNA, Long Non-Protein-Coding Long Noncoding RNA RNA, Long Untranslated Long Untranslated RNA Untranslated RNA, Long Long ncRNAs ncRNAs, Long Long Intergenic Non-Protein Coding RNA Long Intergenic Non-Protein Coding RNA Long Intergenic Non Protein Coding RNA LincRNAs LINC RNA

Below are MeSH descriptors whose meaning is more general than "RNA, Long Noncoding".

Chemicals and Drugs [D]
Nucleic Acids, Nucleotides, and Nucleosides [D13]
Nucleic Acids [D13.444]
RNA [D13.444.735]
RNA, Untranslated [D13.444.735.790]
RNA, Long Noncoding [D13.444.735.790.375]

Below are MeSH descriptors whose meaning is related to "RNA, Long Noncoding".

Below are MeSH descriptors whose meaning is more specific than "RNA, Long Noncoding".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "RNA, Long Noncoding" by people in this website by year, and whether "RNA, Long Noncoding" was a major or minor topic of these publications.

Bar chart showing 101 publications over 23 distinct years, with a maximum of 12 publications in 2024

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2002	0	4	4
2003	0	2	2
2004	0	1	1
2005	0	1	1
2006	0	1	1
2007	0	3	3
2008	0	1	1
2009	0	1	1
2010	0	1	1
2011	0	2	2
2012	1	1	2
2013	6	0	6
2014	7	3	10
2015	6	1	7
2016	7	4	11
2017	4	1	5
2018	6	1	7
2019	3	1	4
2020	7	1	8
2021	1	1	2
2022	4	0	4
2023	6	0	6
2024	11	1	12

Below are the most recent publications written about "RNA, Long Noncoding" by people in Profiles.

Bighetti-Trevisan RL, Almeida LO, Ramos JIR, Freitas GP, Oliveira FS, Gordon JAR, Tye CE, Stein GS, Lian JB, Stein JL, Rosa AL, Beloti MM. The effect of osteoclasts on epigenetic regulation by long non-coding RNAs in osteoblasts grown on titanium with nanotopography. Biomater Adv. 2025 Mar; 168:214128.

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Rahman S, Bloye G, Farah N, Demeulemeester J, Costa JR, O'Connor D, Pocock R, Rapoz-D'Silva T, Turna A, Wang L, Lee S, Fielding AK, Roels J, Jaksik R, Dawidowska M, Van Vlierberghe P, Hadjur S, Hughes JR, Davies JOJ, Gutierrez A, Kelliher MA, Van Loo P, Dawson MA, Mansour MR. Focal deletions of a promoter tether activate the IRX3 oncogene in T-cell acute lymphoblastic leukemia. Blood. 2024 Nov 28; 144(22):2319-2326.

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Shahzad U, Nikolopoulos M, Li C, Johnston M, Wang JJ, Sabha N, Varn FS, Riemenschneider A, Krumholtz S, Krishnamurthy PM, Smith CA, Karamchandani J, Watts JK, Verhaak RGW, Gallo M, Rutka JT, Das S. CASCADES, a novel SOX2 super-enhancer-associated long noncoding RNA, regulates cancer stem cell specification and differentiation in glioblastoma. Mol Oncol. 2025 Mar; 19(3):764-784.

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Livraghi L, Hanly JJ, Evans E, Wright CJ, Loh LS, Mazo-Vargas A, Kamrava K, Carter A, van der Heijden ESM, Reed RD, Papa R, Jiggins CD, Martin A. A long noncoding RNA at the cortex locus controls adaptive coloration in butterflies. Proc Natl Acad Sci U S A. 2024 Sep 03; 121(36):e2403326121.

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Wang F, Mehta P, Bach I. How does the Xist activator Rlim/Rnf12 regulate Xist expression? Biochem Soc Trans. 2024 06 26; 52(3):1099-1107.

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Nickerson JA, Momen-Heravi F. Long non-coding RNAs: roles in cellular stress responses and epigenetic mechanisms regulating chromatin. Nucleus. 2024 Dec; 15(1):2350180.

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O'Reilly ME, Ho S, Coronel J, Zhu L, Liu W, Xue C, Kim E, Cynn E, Matias CV, Soni RK, Wang C, Ionita-Laza I, Bauer RC, Ross L, Zhang Y, Corvera S, Fried SK, Reilly MP. linc-ADAIN, a human adipose lincRNA, regulates adipogenesis by modulating KLF5 and IL-8 mRNA stability. Cell Rep. 2024 05 28; 43(5):114240.

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Sun C, Zhou C, Daneshvar K, Ben Saad A, Kratkiewicz AJ, Toles BJ, Arghiani N, Hess A, Chen JY, Pondick JV, York SR, Li W, Moran SP, Gentile SD, Rahman RU, Li Z, Zhou P, Sparks RP, Habboub T, Kim BM, Choi MY, Affo S, Schwabe RF, Popov YV, Mullen AC. Conserved long noncoding RNA TILAM promotes liver fibrosis through interaction with PML in HSCs. Hepatology. 2025 Mar 01; 81(3):853-869.

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Gupta K, Czerminski JT, Lawrence JB. Trisomy silencing by XIST: translational prospects and challenges. Hum Genet. 2024 Jul; 143(7):843-855.

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Johnson JL, Sargsyan D, Neiman EM, Hart A, Stojmirovic A, Kosoy R, Irizar H, Su?rez-Fari?as M, Song WM, Argmann C, Avey S, Shmuel-Galia L, Vierbuchen T, Bongers G, Sun Y, Edelstein L, Perrigoue J, Towne JE, Hall AO, Fitzgerald KA, Hoebe K. Gene coexpression networks reveal a broad role for lncRNAs in inflammatory bowel disease. JCI Insight. 2024 Feb 08; 9(3).

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