RNA, Long Noncoding

"RNA, Long Noncoding" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A class of untranslated RNA molecules that are typically greater than 200 nucleotides in length and do not code for proteins. Members of this class have been found to play roles in transcriptional regulation, post-transcriptional processing, CHROMATIN REMODELING, and in the epigenetic control of chromatin.

Descriptor ID	D062085
MeSH Number(s)	D13.444.735.790.375
Concept/Terms	RNA, Long Noncoding RNA, Long Noncoding Noncoding RNA, Long lncRNA Long ncRNA ncRNA, Long RNA, Long Non-Translated Long Non-Translated RNA Non-Translated RNA, Long RNA, Long Non Translated Long Non-Coding RNA Long Non Coding RNA Non-Coding RNA, Long RNA, Long Non-Coding Long Non-Protein-Coding RNA Long Non Protein Coding RNA Non-Protein-Coding RNA, Long RNA, Long Non-Protein-Coding Long Noncoding RNA RNA, Long Untranslated Long Untranslated RNA Untranslated RNA, Long Long ncRNAs ncRNAs, Long Long Intergenic Non-Protein Coding RNA Long Intergenic Non-Protein Coding RNA Long Intergenic Non Protein Coding RNA LincRNAs LINC RNA

Below are MeSH descriptors whose meaning is more general than "RNA, Long Noncoding".

Chemicals and Drugs [D]
Nucleic Acids, Nucleotides, and Nucleosides [D13]
Nucleic Acids [D13.444]
RNA [D13.444.735]
RNA, Untranslated [D13.444.735.790]
RNA, Long Noncoding [D13.444.735.790.375]

Below are MeSH descriptors whose meaning is related to "RNA, Long Noncoding".

Below are MeSH descriptors whose meaning is more specific than "RNA, Long Noncoding".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "RNA, Long Noncoding" by people in this website by year, and whether "RNA, Long Noncoding" was a major or minor topic of these publications.

Bar chart showing 81 publications over 22 distinct years, with a maximum of 11 publications in 2016

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2002	0	4	4
2003	0	2	2
2004	0	1	1
2005	0	1	1
2006	0	1	1
2007	0	3	3
2008	0	1	1
2009	0	1	1
2010	0	1	1
2011	0	2	2
2012	1	1	2
2013	6	0	6
2014	6	3	9
2015	5	1	6
2016	7	4	11
2017	3	0	3
2018	6	1	7
2019	4	1	5
2020	7	2	9
2021	1	1	2
2022	3	0	3
2023	1	0	1

Below are the most recent publications written about "RNA, Long Noncoding" by people in Profiles.

Landshammer A, Bolondi A, Kretzmer H, Much C, Buschow R, Rose A, Wu HJ, Mackowiak SD, Braendl B, Giesselmann P, Tornisiello R, Parsi KM, Huey J, Mielke T, Meierhofer D, Maehr R, Hnisz D, Michor F, Rinn JL, Meissner A. T-REX17 is a transiently expressed non-coding RNA essential for human endoderm formation. Elife. 2023 01 31; 12.

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Vierbuchen T, Agarwal S, Johnson JL, Galia L, Lei X, Stein K, Olagnier D, Gaede KI, Herzmann C, Holm CK, Heine H, Pai A, O'Hara Hall A, Hoebe K, Fitzgerald KA. The lncRNA LUCAT1 is elevated in inflammatory disease and restrains inflammation by regulating the splicing and stability of NR4A2. Proc Natl Acad Sci U S A. 2023 01 03; 120(1):e2213715120.

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MacMillan HJ, Kong Y, Calvo-Roitberg E, Alonso LC, Pai AA. High-throughput analysis of ANRIL circRNA isoforms in human pancreatic islets. Sci Rep. 2022 05 11; 12(1):7745.

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Tye CE, Ghule PN, Gordon JAR, Kabala FS, Page NA, Falcone MM, Tracy KM, van Wijnen AJ, Stein JL, Lian JB, Stein GS. LncMIR181A1HG is a novel chromatin-bound epigenetic suppressor of early stage osteogenic lineage commitment. Sci Rep. 2022 05 11; 12(1):7770.

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Kolpa HJ, Creamer KM, Hall LL, Lawrence JB. SAF-A mutants disrupt chromatin structure through dominant negative effects on RNAs associated with chromatin. Mamm Genome. 2022 06; 33(2):366-381.

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Creamer KM, Kolpa HJ, Lawrence JB. Nascent RNA scaffolds contribute to chromosome territory architecture and counter chromatin compaction. Mol Cell. 2021 09 02; 81(17):3509-3525.e5.

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Agarwal S, Vierbuchen T, Ghosh S, Chan J, Jiang Z, Kandasamy RK, Ricci E, Fitzgerald KA. The long non-coding RNA LUCAT1 is a negative feedback regulator of interferon responses in humans. Nat Commun. 2020 12 11; 11(1):6348.

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Daneshvar K, Ardehali MB, Klein IA, Hsieh FK, Kratkiewicz AJ, Mahpour A, Cancelliere SOL, Zhou C, Cook BM, Li W, Pondick JV, Gupta SK, Moran SP, Young RA, Kingston RE, Mullen AC. lncRNA DIGIT and BRD3 protein form phase-separated condensates to regulate endoderm differentiation. Nat Cell Biol. 2020 10; 22(10):1211-1222.

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Das S, Shah R, Dimmeler S, Freedman JE, Holley C, Lee JM, Moore K, Musunuru K, Wang DZ, Xiao J, Yin KJ. Noncoding RNAs in Cardiovascular Disease: Current Knowledge, Tools and Technologies for Investigation, and Future Directions: A Scientific Statement From the American Heart Association. Circ Genom Precis Med. 2020 08; 13(4):e000062.

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Vierbuchen T, Fitzgerald KA. Long non-coding RNAs in antiviral immunity. Semin Cell Dev Biol. 2021 03; 111:126-134.

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