"HLA-DR alpha-Chains" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Transmembrane proteins that form the alpha subunits of the HLA-DR antigens. They are also referred to as the HLA-DR heavy chains.
| Descriptor ID |
D059805
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| MeSH Number(s) |
D12.776.395.550.509.400.440.100 D12.776.543.550.440.400.440.100 D23.050.301.500.400.400.440.100 D23.050.301.500.450.400.440.222 D23.050.705.552.410.400.440.100 D23.050.705.552.450.400.440.222
|
| Concept/Terms |
HLA-DR alpha-Chains- HLA-DR alpha-Chains
- HLA DR alpha Chains
- alpha-Chains, HLA-DR
- HLA-DRA
- HLA-DR alpha-Chain
- HLA DR alpha Chain
- alpha-Chain, HLA-DR
- MHC Class II Antigen DRA
- HLA-DR Heavy Chain
- HLA DR Heavy Chain
- Heavy Chain, HLA-DR
- HLA-DR alpha
- HLA DR alpha
- HLA Class II Histocompatibility Antigen, DR alpha Chain
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Below are MeSH descriptors whose meaning is more general than "HLA-DR alpha-Chains".
Below are MeSH descriptors whose meaning is more specific than "HLA-DR alpha-Chains".
This graph shows the total number of publications written about "HLA-DR alpha-Chains" by people in this website by year, and whether "HLA-DR alpha-Chains" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2014 | 0 | 1 | 1 |
| 2018 | 0 | 1 | 1 |
| 2019 | 1 | 0 | 1 |
| 2026 | 1 | 0 | 1 |
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Below are the most recent publications written about "HLA-DR alpha-Chains" by people in Profiles.
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Aydemir O, Bailey JA, Agardh D, Lernmark ?, Noble JA, Andersson Sv?rd A, Blankenhorn EP, Parikh HM, Ziegler AG, Toppari J, Akolkar B, Hagopian WA, Rewers MJ, Mordes JP. Polymorphisms in intron 1 of HLA-DRA differentially associate with type 1 diabetes and celiac disease and implicate involvement of complement system genes C4A and C4B. Elife. 2026 Feb 02; 12.
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Aydemir ?, Noble JA, Bailey JA, Lernmark ?, Marsh P, Andersson Sv?rd A, Bearoff F, Blankenhorn EP, Mordes JP. Genetic Variation Within the HLA-DRA1 Gene Modulates Susceptibility to Type 1 Diabetes in HLA-DR3 Homozygotes. Diabetes. 2019 07; 68(7):1523-1527.
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Aliseychik MP, Andreeva TV, Rogaev EI. Immunogenetic Factors of Neurodegenerative Diseases: The Role of HLA Class II. Biochemistry (Mosc). 2018 Sep; 83(9):1104-1116.
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Yin L, Stern LJ. A novel method to measure HLA-DM-susceptibility of peptides bound to MHC class II molecules based on peptide binding competition assay and differential IC(50) determination. J Immunol Methods. 2014 Apr; 406:21-33.