Clustered Regularly Interspaced Short Palindromic Repeats

"Clustered Regularly Interspaced Short Palindromic Repeats" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Repetitive nucleic acid sequences that are principal components of the archaeal and bacterial CRISPR-CAS SYSTEMS, which function as adaptive antiviral defense systems.

Descriptor ID	D064112
MeSH Number(s)	G02.111.570.080.708.800.325.500 G05.360.080.708.800.325.500 G05.360.340.024.850.069
Concept/Terms	Clustered Regularly Interspaced Short Palindromic Repeats Clustered Regularly Interspaced Short Palindromic Repeats CRISPRs CRISPR CRISPR Sequences CRISPR Sequence Sequence, CRISPR Sequences, CRISPR Clustered Regularly Interspaced Short Palindromic Repeat CRISPR Elements CRISPR Element Element, CRISPR Elements, CRISPR CRISPR Spacers CRISPR Spacers CRISPR Spacer Spacer, CRISPR Spacers, CRISPR CRISPR Spacer Sequences CRISPR Spacer Sequence Sequence, CRISPR Spacer Sequences, CRISPR Spacer Spacer Sequence, CRISPR Spacer Sequences, CRISPR CRISPR-Cas Loci CRISPR-Cas Loci CRISPR Cas Loci CRISPR-Cas Locus Loci, CRISPR-Cas Locus, CRISPR-Cas CRISPR Loci CRISPR Loci Loci, CRISPR Locus, CRISPR CRISPR Clusters CRISPR Cluster Cluster, CRISPR Clusters, CRISPR CRISPR Locus CRISPR Arrays Array, CRISPR Arrays, CRISPR CRISPR Array

Below are MeSH descriptors whose meaning is more general than "Clustered Regularly Interspaced Short Palindromic Repeats".

Biological Sciences [G]
Chemical Phenomena [G02]
Biochemical Phenomena [G02.111]
Molecular Structure [G02.111.570]
Base Sequence [G02.111.570.080]
Repetitive Sequences, Nucleic Acid [G02.111.570.080.708]
Tandem Repeat Sequences [G02.111.570.080.708.800]
Inverted Repeat Sequences [G02.111.570.080.708.800.325]
Clustered Regularly Interspaced Short Palindromic Repeats [G02.111.570.080.708.800.325.500]
Genetic Phenomena [G05]
Genetic Structures [G05.360]
Base Sequence [G05.360.080]
Repetitive Sequences, Nucleic Acid [G05.360.080.708]
Tandem Repeat Sequences [G05.360.080.708.800]
Inverted Repeat Sequences [G05.360.080.708.800.325]
Clustered Regularly Interspaced Short Palindromic Repeats [G05.360.080.708.800.325.500]
Genome [G05.360.340]
Genome Components [G05.360.340.024]
Tandem Repeat Sequences [G05.360.340.024.850]
Clustered Regularly Interspaced Short Palindromic Repeats [G05.360.340.024.850.069]

Below are MeSH descriptors whose meaning is related to "Clustered Regularly Interspaced Short Palindromic Repeats".

Below are MeSH descriptors whose meaning is more specific than "Clustered Regularly Interspaced Short Palindromic Repeats".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Clustered Regularly Interspaced Short Palindromic Repeats" by people in this website by year, and whether "Clustered Regularly Interspaced Short Palindromic Repeats" was a major or minor topic of these publications.

Bar chart showing 50 publications over 8 distinct years, with a maximum of 11 publications in 2018

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2014	2	3	5
2015	5	2	7
2016	5	1	6
2017	2	2	4
2018	4	7	11
2019	4	0	4
2020	4	6	10
2021	2	1	3

Below are the most recent publications written about "Clustered Regularly Interspaced Short Palindromic Repeats" by people in Profiles.

Keeler AM. Immune Responses to Adeno-Associated Virus-Mediated CRISPR Therapy. Hum Gene Ther. 2021 Dec; 32(23-24):1430-1432.

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Flotte TR. CRISPR Keeps Things Fresh: Next-Generation Tools for Gene Editing. Hum Gene Ther. 2021 03; 32(5-6):235-236.

View in: PubMed
E X, Kowalik TF. A Generally Applicable CRISPR/Cas9 Screening Technique to Identify Host Genes Required for Virus Infection as Applied to Human Cytomegalovirus (HCMV) Infection of Epithelial Cells. Methods Mol Biol. 2021; 2244:247-264.

View in: PubMed
Miyata H, Abbasi F, Visconti PE, Ikawa M. CRISPR/CAS9-mediated amino acid substitution reveals phosphorylation residues of RSPH6A are not essential for male fertility in mice†. Biol Reprod. 2020 10 29; 103(5):912-914.

View in: PubMed
Barnes KG, Lachenauer AE, Nitido A, Siddiqui S, Gross R, Beitzel B, Siddle KJ, Freije CA, Dighero-Kemp B, Mehta SB, Carter A, Uwanibe J, Ajogbasile F, Olumade T, Odia I, Sandi JD, Momoh M, Metsky HC, Boehm CK, Lin AE, Kemball M, Park DJ, Branco L, Boisen M, Sullivan B, Amare MF, Tiamiyu AB, Parker ZF, Iroezindu M, Grant DS, Modjarrad K, Myhrvold C, Garry RF, Palacios G, Hensley LE, Schaffner SF, Happi CT, Colubri A, Sabeti PC. Deployable CRISPR-Cas13a diagnostic tools to detect and report Ebola and Lassa virus cases in real-time. Nat Commun. 2020 08 17; 11(1):4131.

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Barrangou R, Sontheimer EJ. Shutting down RNA-targeting CRISPR. Science. 2020 07 03; 369(6499):31-32.

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Chatterjee P, Jakimo N, Lee J, Amrani N, Rodríguez T, Koseki SRT, Tysinger E, Qing R, Hao S, Sontheimer EJ, Jacobson J. An engineered ScCas9 with broad PAM range and high specificity and activity. Nat Biotechnol. 2020 10; 38(10):1154-1158.

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Foda BM, Ciecko AE, Serreze DV, Ridgway WM, Geurts AM, Chen YG. The CD137 Ligand Is Important for Type 1 Diabetes Development but Dispensable for the Homeostasis of Disease-Suppressive CD137+ FOXP3+ Regulatory CD4 T Cells. J Immunol. 2020 06 01; 204(11):2887-2899.

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Ohainle M, Kim K, Komurlu Keceli S, Felton A, Campbell E, Luban J, Emerman M. TRIM34 restricts HIV-1 and SIV capsids in a TRIM5?-dependent manner. PLoS Pathog. 2020 04; 16(4):e1008507.

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Krishnan G, Zhang Y, Gu Y, Kankel MW, Gao FB, Almeida S. CRISPR deletion of the C9ORF72 promoter in ALS/FTD patient motor neurons abolishes production of dipeptide repeat proteins and rescues neurodegeneration. Acta Neuropathol. 2020 07; 140(1):81-84.

View in: PubMed

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