"Complement C4a" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The smaller fragment formed when complement C4 is cleaved by COMPLEMENT C1S. It is an anaphylatoxin that causes symptoms of immediate hypersensitivity (HYPERSENSITIVITY, IMMEDIATE) but its activity is weaker than that of COMPLEMENT C3A or COMPLEMENT C5A.
| Descriptor ID |
D015934
|
| MeSH Number(s) |
D12.776.124.486.274.024.260 D12.776.124.486.274.350.250
|
| Concept/Terms |
Complement C4a- Complement C4a
- C4a, Complement
- Complement Component 4a
- Component 4a, Complement
- C4a Complement
- Complement, C4a
- Complement 4a
|
Below are MeSH descriptors whose meaning is more general than "Complement C4a".
Below are MeSH descriptors whose meaning is more specific than "Complement C4a".
This graph shows the total number of publications written about "Complement C4a" by people in this website by year, and whether "Complement C4a" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2021 | 0 | 1 | 1 |
| 2026 | 1 | 0 | 1 |
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Below are the most recent publications written about "Complement C4a" by people in Profiles.
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Aydemir O, Bailey JA, Agardh D, Lernmark ?, Noble JA, Andersson Sv?rd A, Blankenhorn EP, Parikh HM, Ziegler AG, Toppari J, Akolkar B, Hagopian WA, Rewers MJ, Mordes JP. Polymorphisms in intron 1 of HLA-DRA differentially associate with type 1 diabetes and celiac disease and implicate involvement of complement system genes C4A and C4B. Elife. 2026 Feb 02; 12.
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Kalinowski A, Liliental J, Anker LA, Linkovski O, Culbertson C, Hall JN, Pattni R, Sabatti C, Noordsy D, Hallmayer JF, Mellins ED, Ballon JS, O'Hara R, Levinson DF, Urban AE. Increased activation product of complement 4 protein in plasma of individuals with schizophrenia. Transl Psychiatry. 2021 09 22; 11(1):486.
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Agostoni A, Gardinali M, Frangi D, Cugno M, Cafaro C, Conciato L, Sponzilli C, Salmoirago E. Thrombolytic treatment and complement activation. Ann Ital Med Int. 1994 Jul-Sep; 9(3):178-9.