GTP-Binding Protein alpha Subunits, Gi-Go

"GTP-Binding Protein alpha Subunits, Gi-Go" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A family of heterotrimeric GTP-binding protein alpha subunits that were originally identified by their ability to inhibit ADENYLYL CYCLASES. Members of this family can couple to beta and gamma G-protein subunits that activate POTASSIUM CHANNELS. The Gi-Go part of the name is also spelled Gi/Go.

Descriptor ID	D019206
MeSH Number(s)	D08.811.277.040.330.300.200.100.200 D12.644.360.360.100.200 D12.776.157.325.332.100.200 D12.776.476.375.100.200 D12.776.543.325.100.200
Concept/Terms	GTP-Binding Protein alpha Subunits, Gi-Go GTP-Binding Protein alpha Subunits, Gi-Go GTP Binding Protein alpha Subunits, Gi Go G-Protein, Gi-Go Subunits G Protein, Gi Go Subunits Gi-Go Subunits G-Protein Subunits G-Protein, Gi-Go Gi-Go G-Proteins G-Proteins, Gi-Go Gi Go G Proteins G-Protein, Gi-Go alpha Family G Protein, Gi Go alpha Family GTP-Binding Protein alpha Subunit, GoC GTP-Binding Protein alpha Subunit, GoC GTP Binding Protein alpha Subunit, GoC G Protein Subunit alphaoC GTP-Binding Protein alpha Subunit, Go1 GTP-Binding Protein alpha Subunit, Go1 GTP Binding Protein alpha Subunit, Go1 G-Protein, Go1 Subunit G Protein, Go1 Subunit Go1 Subunit G-Protein Subunit G-Protein, Go1 G(o1)alpha GTP-Binding Protein alpha Subunit, GoA GTP-Binding Protein alpha Subunit, GoA GTP Binding Protein alpha Subunit, GoA G Protein Subunit alphaoA GTP-Binding Protein alpha Subunit, Go GTP-Binding Protein alpha Subunit, Go GTP Binding Protein alpha Subunit, Go Guanine Nucleotide-Binding Protein Go Guanine Nucleotide Binding Protein Go Go Alpha Subunit Alpha Subunit, Go Subunit, Go Alpha G-Protein, Inhibitory Go G Protein, Inhibitory Go Go G-Protein, Inhibitory Inhibitory Go G-Protein G-Protein, Go Subunit G Protein, Go Subunit Go Subunit G-Protein Subunit G-Protein, Go G Protein Go Go, G Protein G(o) Protein GTP-Binding Protein alpha Subunit, Gi GTP-Binding Protein alpha Subunit, Gi GTP Binding Protein alpha Subunit, Gi Gi, Inhibitory G-Protein Gi, Inhibitory G Protein Inhibitory G-Protein Gi G-Protein, Inhibitory Gi G Protein, Inhibitory Gi Gi G-Protein, Inhibitory Inhibitory Gi G-Protein G-Protein, Gi Subunit G Protein, Gi Subunit Gi Subunit G-Protein Subunit G-Protein, Gi Gi alpha Subunit Subunit, Gi alpha alpha Subunit, Gi Ni Protein Gi-Alpha Protein Gi Alpha Protein

Below are MeSH descriptors whose meaning is more general than "GTP-Binding Protein alpha Subunits, Gi-Go".

Chemicals and Drugs [D]
Enzymes and Coenzymes [D08]
Enzymes [D08.811]
Hydrolases [D08.811.277]
Acid Anhydride Hydrolases [D08.811.277.040]
GTP Phosphohydrolases [D08.811.277.040.330]
GTP-Binding Proteins [D08.811.277.040.330.300]
Heterotrimeric GTP-Binding Proteins [D08.811.277.040.330.300.200]
GTP-Binding Protein alpha Subunits [D08.811.277.040.330.300.200.100]
GTP-Binding Protein alpha Subunits, Gi-Go [D08.811.277.040.330.300.200.100.200]
Amino Acids, Peptides, and Proteins [D12]
Peptides [D12.644]
Intracellular Signaling Peptides and Proteins [D12.644.360]
Heterotrimeric GTP-Binding Proteins [D12.644.360.360]
GTP-Binding Protein alpha Subunits [D12.644.360.360.100]
GTP-Binding Protein alpha Subunits, Gi-Go [D12.644.360.360.100.200]
Proteins [D12.776]
Carrier Proteins [D12.776.157]
GTP-Binding Proteins [D12.776.157.325]
Heterotrimeric GTP-Binding Proteins [D12.776.157.325.332]
GTP-Binding Protein alpha Subunits [D12.776.157.325.332.100]
GTP-Binding Protein alpha Subunits, Gi-Go [D12.776.157.325.332.100.200]
Intracellular Signaling Peptides and Proteins [D12.776.476]
Heterotrimeric GTP-Binding Proteins [D12.776.476.375]
GTP-Binding Protein alpha Subunits [D12.776.476.375.100]
GTP-Binding Protein alpha Subunits, Gi-Go [D12.776.476.375.100.200]
Membrane Proteins [D12.776.543]
Heterotrimeric GTP-Binding Proteins [D12.776.543.325]
GTP-Binding Protein alpha Subunits [D12.776.543.325.100]
GTP-Binding Protein alpha Subunits, Gi-Go [D12.776.543.325.100.200]

Below are MeSH descriptors whose meaning is related to "GTP-Binding Protein alpha Subunits, Gi-Go".

Below are MeSH descriptors whose meaning is more specific than "GTP-Binding Protein alpha Subunits, Gi-Go".

GTP-Binding Protein alpha Subunits, Gi-Go
GTP-Binding Protein alpha Subunit, Gi2

publications

Timeline | Most Recent

This graph shows the total number of publications written about "GTP-Binding Protein alpha Subunits, Gi-Go" by people in this website by year, and whether "GTP-Binding Protein alpha Subunits, Gi-Go" was a major or minor topic of these publications.

Bar chart showing 11 publications over 9 distinct years, with a maximum of 2 publications in 2004 and 2013

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1998	1	0	1
2000	1	0	1
2002	1	0	1
2004	2	0	2
2010	0	1	1
2013	1	1	2
2016	1	0	1
2019	0	1	1
2024	1	0	1

Below are the most recent publications written about "GTP-Binding Protein alpha Subunits, Gi-Go" by people in Profiles.

Roy AJ, Leipprandt JR, Patterson JR, Stoll AC, Kemp CJ, Oula ZD, Mola T, Batista AR, Sortwell CE, Sena-Esteves M, Neubig RR. AAV9-Mediated Intrastriatal Delivery of GNAO1 Reduces Hyperlocomotion in Gnao1 Heterozygous R209H Mutant Mice. J Pharmacol Exp Ther. 2024 Jul 18; 390(2):250-259.

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Zurawski Z, Thompson Gray AD, Brady LJ, Page B, Church E, Harris NA, Dohn MR, Yim YY, Hyde K, Mortlock DP, Jones CK, Winder DG, Alford S, Hamm HE. Disabling the G??-SNARE interaction disrupts GPCR-mediated presynaptic inhibition, leading to physiological and behavioral phenotypes. Sci Signal. 2019 02 19; 12(569).

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Pratt CH, Dionne LA, Fairfield H, Dadras SS, Potter CS, Sundberg JP. Gnaq(M1J): An ENU-Induced Mutant Allele Affecting Pigmentation in the Mouse. J Invest Dermatol. 2016 Jan; 136(1):334-336.

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Donnelly JL, Clark CM, Leifer AM, Pirri JK, Haburcak M, Francis MM, Samuel AD, Alkema MJ. Monoaminergic orchestration of motor programs in a complex C. elegans behavior. PLoS Biol. 2013; 11(4):e1001529.

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Los FC, Ha C, Aroian RV. Neuronal Goa and CAPS regulate behavioral and immune responses to bacterial pore-forming toxins. PLoS One. 2013; 8(1):e54528.

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Fenton RA, Shea LG, Doddi C, Dobson JG. Myocardial adenosine A(1)-receptor-mediated adenoprotection involves phospholipase C, PKC-epsilon, and p38 MAPK, but not HSP27. Am J Physiol Heart Circ Physiol. 2010 Jun; 298(6):H1671-8.

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Vanhoose AM, Ritchie MD, Winder DG. Regulation of cAMP levels in area CA1 of hippocampus by Gi/o-coupled receptors is stimulus dependent in mice. Neurosci Lett. 2004 Nov 03; 370(1):80-3.

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Bauer A, McDonald AD, Nasir K, Peller L, Rade JJ, Miller JM, Heldman AW, Donahue JK. Inhibitory G protein overexpression provides physiologically relevant heart rate control in persistent atrial fibrillation. Circulation. 2004 Nov 09; 110(19):3115-20.

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Janssen PM, Schillinger W, Donahue JK, Zeitz O, Emami S, Lehnart SE, Weil J, Eschenhagen T, Hasenfuss G, Prestle J. Intracellular beta-blockade: overexpression of Galpha(i2) depresses the beta-adrenergic response in intact myocardium. Cardiovasc Res. 2002 Aug 01; 55(2):300-8.

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Donahue JK, Heldman AW, Fraser H, McDonald AD, Miller JM, Rade JJ, Eschenhagen T, Marb?n E. Focal modification of electrical conduction in the heart by viral gene transfer. Nat Med. 2000 Dec; 6(12):1395-8.

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