Cholesterol crystals induce complement-dependent inflammasome activation and cytokine release.
Samstad EO, Niyonzima N, Nymo S, Aune MH, Ryan L, Bakke SS, Lappeg?rd KT, Brekke OL, Lambris JD, Dam?s JK, Latz E, Mollnes TE, Espevik T. Cholesterol crystals induce complement-dependent inflammasome activation and cytokine release. J Immunol. 2014 Mar 15; 192(6):2837-45.