beta-Lactams

"beta-Lactams" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Four-membered cyclic AMIDES, best known for the PENICILLINS based on a bicyclo-thiazolidine, as well as the CEPHALOSPORINS based on a bicyclo-thiazine, and including monocyclic MONOBACTAMS. The BETA-LACTAMASES hydrolyze the beta lactam ring, accounting for BETA-LACTAM RESISTANCE of infective bacteria.

Descriptor ID	D047090
MeSH Number(s)	D02.065.589.099 D02.886.108 D03.633.100.300
Concept/Terms	beta-Lactams beta-Lactams beta Lactams 4-Thia-1-Azabicyclo(4.2.0)Octanes 4-Thia-1-Azabicyclo(4.2.0)Octanes 4-Thia-1-Azabicyclo(3.2.0)Heptanes 4-Thia-1-Azabicyclo(3.2.0)Heptanes

Below are MeSH descriptors whose meaning is more general than "beta-Lactams".

Chemicals and Drugs [D]
Organic Chemicals [D02]
Amides [D02.065]
Lactams [D02.065.589]
beta-Lactams [D02.065.589.099]
Sulfur Compounds [D02.886]
beta-Lactams [D02.886.108]
Heterocyclic Compounds [D03]
Heterocyclic Compounds, Fused-Ring [D03.633]
Heterocyclic Compounds, 2-Ring [D03.633.100]
beta-Lactams [D03.633.100.300]

Below are MeSH descriptors whose meaning is related to "beta-Lactams".

Below are MeSH descriptors whose meaning is more specific than "beta-Lactams".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "beta-Lactams" by people in this website by year, and whether "beta-Lactams" was a major or minor topic of these publications.

Bar chart showing 7 publications over 5 distinct years, with a maximum of 2 publications in 2012 and 2023

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1997	0	1	1
2012	1	1	2
2013	0	1	1
2020	0	1	1
2023	0	2	2

Below are the most recent publications written about "beta-Lactams" by people in Profiles.

Merz LE, Huang GX, Mehta GD, Lynch DM, Maliborski N, Besz K, Wickner P, Cutler C, Castells M. Development of a Pipeline for Removing Allergy Labels in Patients Undergoing Hematopoietic Stem Cell Transplantation. Transplant Cell Ther. 2024 Mar; 30(3):322.e1-322.e10.

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Raku?a E, Fink A, Tamg?ney G, Heneka MT, Doblhammer G. Sporadic Use of Antibiotics in Older Adults and the Risk of Dementia: A Nested Case-Control Study Based on German Health Claims Data. J Alzheimers Dis. 2023; 93(4):1329-1339.

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Arensman K, Shields M, Beganovic M, Miller JL, LaChance E, Anderson M, Dela-Pena J. Fluoroquinolone versus Beta-Lactam Oral Step-Down Therapy for Uncomplicated Streptococcal Bloodstream Infections. Antimicrob Agents Chemother. 2020 10 20; 64(11).

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Fukuda T, Matsumura T, Ato M, Hamasaki M, Nishiuchi Y, Murakami Y, Maeda Y, Yoshimori T, Matsumoto S, Kobayashi K, Kinoshita T, Morita YS. Critical roles for lipomannan and lipoarabinomannan in cell wall integrity of mycobacteria and pathogenesis of tuberculosis. mBio. 2013 Feb 19; 4(1):e00472-12.

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Brown S, Xia G, Luhachack LG, Campbell J, Meredith TC, Chen C, Winstel V, Gekeler C, Irazoqui JE, Peschel A, Walker S. Methicillin resistance in Staphylococcus aureus requires glycosylated wall teichoic acids. Proc Natl Acad Sci U S A. 2012 Nov 13; 109(46):18909-14.

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Fong JJ, Ros? L, Radigan EA. Clinical outcomes with ertapenem as a first-line treatment option of infections caused by extended-spectrum ?-lactamase producing gram-negative bacteria. Ann Pharmacother. 2012 Mar; 46(3):347-52.

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Bliziotis IA, Michalopoulos A, Kasiakou SK, Samonis G, Christodoulou C, Chrysanthopoulou S, Falagas ME. Ciprofloxacin vs an aminoglycoside in combination with a beta-lactam for the treatment of febrile neutropenia: a meta-analysis of randomized controlled trials. Mayo Clin Proc. 2005 Sep; 80(9):1146-56.

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Bliziotis IA, Samonis G, Vardakas KZ, Chrysanthopoulou S, Falagas ME. Effect of aminoglycoside and beta-lactam combination therapy versus beta-lactam monotherapy on the emergence of antimicrobial resistance: a meta-analysis of randomized, controlled trials. Clin Infect Dis. 2005 Jul 15; 41(2):149-58.

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Craiu A, Gaczynska M, Akopian T, Gramm CF, Fenteany G, Goldberg AL, Rock KL. Lactacystin and clasto-lactacystin beta-lactone modify multiple proteasome beta-subunits and inhibit intracellular protein degradation and major histocompatibility complex class I antigen presentation. J Biol Chem. 1997 May 16; 272(20):13437-45.

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Shen YQ, Wolfe S, Demain AL. Enzymatic conversion of the unnatural tripeptide delta-(D-alpha-aminoadipyl)-L-cysteinyl-D-valine to beta-lactam antibiotics. J Antibiot (Tokyo). 1984 Sep; 37(9):1044-8.

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