Lipase

"Lipase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

An enzyme of the hydrolase class that catalyzes the reaction of triacylglycerol and water to yield diacylglycerol and a fatty acid anion. It is produced by glands on the tongue and by the pancreas and initiates the digestion of dietary fats. (From Dorland, 27th ed) EC 3.1.1.3.

Descriptor ID	D008049
MeSH Number(s)	D08.811.277.352.100.400
Concept/Terms	Lipase Lipase Triacylglycerol Lipase Triolean Hydrolase Hydrolase, Triolean Triglyceridase Triglyceride Lipase Lipase, Triglyceride Triacylglycerol Hydrolase Hydrolase, Triacylglycerol Tributyrinase Acid Lipase A Acid Lipase A Lipase A, Acid Monoester Lipase Monoester Lipase Lipase, Monoester Acid Lipase I Acid Lipase I Lipase I, Acid Acid Lipase II Acid Lipase II Lipase II, Acid Exolipase Exolipase Acid Lipase Acid Lipase Lipase, Acid Acid Lipase B Acid Lipase B Lipase B, Acid

Below are MeSH descriptors whose meaning is more general than "Lipase".

Chemicals and Drugs [D]
Enzymes and Coenzymes [D08]
Enzymes [D08.811]
Hydrolases [D08.811.277]
Esterases [D08.811.277.352]
Carboxylic Ester Hydrolases [D08.811.277.352.100]
Lipase [D08.811.277.352.100.400]

Below are MeSH descriptors whose meaning is related to "Lipase".

Below are MeSH descriptors whose meaning is more specific than "Lipase".

Lipase
Pancrelipase

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Lipase" by people in this website by year, and whether "Lipase" was a major or minor topic of these publications.

Bar chart showing 45 publications over 17 distinct years, with a maximum of 10 publications in 2010

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2003	1	0	1
2004	0	1	1
2006	1	0	1
2008	2	1	3
2010	6	4	10
2011	3	1	4
2012	0	1	1
2014	3	1	4
2015	1	0	1
2016	2	0	2
2017	3	0	3
2018	0	2	2
2019	0	1	1
2020	1	1	2
2021	0	1	1
2024	3	2	5
2025	1	2	3

Below are the most recent publications written about "Lipase" by people in Profiles.

Ma D, Li A, Xie M, McClements DJ, Chen J. Raffinose esters of long-chain unsaturated fatty acids: Preparation, characterization, and in vitro digestive behavior. Food Res Int. 2025 Oct; 217:116772.

View in: PubMed
Wang Y, Cheng J, McClements DJ, Chen J, Ma D. A novel synergistic inhibition mechanism of pancreatic lipase by 2-mercaptobenzothiazole and stearic acid migrants from dairy contact rubbers. Food Chem. 2025 Jul 01; 479:143816.

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Cao M, Yang F, Zhang Y, McClements DJ, Liu R, Chang M, Wang X, Zhu Y, Zhang H, Wei W, Wang X. Efficient method of synthesizing sn-2 eicosapentaenoic acid (EPA) monoacylglycerols using circular ethanolysis and glycerolysis. Food Chem. 2025 May 15; 474:143047.

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Guan W, Cheng J, McClements DJ, Tu Z, Chen J, Ma D. Impact of 2,4-di-tert-butylphenol on pancreatic lipase activity in emulsions: Multispectral, molecular docking, and in vitro digestion analysis. Food Chem. 2025 Apr 01; 470:142730.

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Gu F, Wen Y, Hu X, Liao H, He C, McClements DJ, Pan W, Niu F. Novel Porous Starch Granules Fabricated Using Controlled Lipase-Amylase Treatments: Application as Delivery Systems and Resistant Starches. J Agric Food Chem. 2024 Nov 06; 72(44):24762-24775.

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Desai A, Loureiro ZY, DeSouza T, Yang Q, Solivan-Rivera J, Corvera S. cAMP driven UCP1 induction in human adipocytes requires ATGL-catalyzed lipolysis. Mol Metab. 2024 Dec; 90:102051.

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Singh A, Abhilasha KV, Acharya KR, Liu H, Nirala NK, Parthibane V, Kunduri G, Abimannan T, Tantalla J, Zhu LJ, Acharya JK, Acharya UR. A nutrient responsive lipase mediates gut-brain communication to regulate insulin secretion in Drosophila. Nat Commun. 2024 May 23; 15(1):4410.

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Huang G, McClements DJ, He K, Lin Z, Zhang Z, Zhang R, Jin Z, Chen L. Recent advances in enzymatic modification techniques to improve the quality of flour-based fried foods. Crit Rev Food Sci Nutr. 2025; 65(13):2609-2624.

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McGuire SP, Maatman TK, Keller SL, Ceppa EP, House MG, Nakeeb A, Nguyen TK, Schmidt CM, Zyromski NJ. Early postoperative serum hyperamylasemia: Harbinger of morbidity hiding in plain sight? Surgery. 2022 02; 171(2):469-475.

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Rozeveld CN, Johnson KM, Zhang L, Razidlo GL. KRAS Controls Pancreatic Cancer Cell Lipid Metabolism and Invasive Potential through the Lipase HSL. Cancer Res. 2020 11 15; 80(22):4932-4945.

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