Proton Pump Inhibitors

"Proton Pump Inhibitors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Compounds that inhibit H(+)-K(+)-EXCHANGING ATPASE. They are used as ANTI-ULCER AGENTS and sometimes in place of HISTAMINE H2 ANTAGONISTS for GASTROESOPHAGEAL REFLUX.

Descriptor ID	D054328
MeSH Number(s)	D27.505.519.389.848
Concept/Terms	Proton Pump Inhibitors Proton Pump Inhibitors Inhibitors, Proton Pump

Below are MeSH descriptors whose meaning is more general than "Proton Pump Inhibitors".

Chemicals and Drugs [D]
Chemical Actions and Uses [D27]
Pharmacologic Actions [D27.505]
Molecular Mechanisms of Pharmacological Action [D27.505.519]
Enzyme Inhibitors [D27.505.519.389]
Proton Pump Inhibitors [D27.505.519.389.848]

Below are MeSH descriptors whose meaning is related to "Proton Pump Inhibitors".

Below are MeSH descriptors whose meaning is more specific than "Proton Pump Inhibitors".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Proton Pump Inhibitors" by people in this website by year, and whether "Proton Pump Inhibitors" was a major or minor topic of these publications.

Bar chart showing 32 publications over 16 distinct years, with a maximum of 4 publications in 2012 and 2013

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2006	1	0	1
2007	0	1	1
2009	2	0	2
2010	2	0	2
2011	2	0	2
2012	4	0	4
2013	2	2	4
2014	1	1	2
2015	1	1	2
2017	0	1	1
2018	1	0	1
2019	1	2	3
2021	1	1	2
2022	1	2	3
2024	0	1	1
2025	1	0	1

Below are the most recent publications written about "Proton Pump Inhibitors" by people in Profiles.

Rosenberg M, Perez Coulter A, Pepper V, Banever G, Tashjian D, Moriarty K, Tirabassi MV. Long-Term Efficacy of Pediatric Anti-reflux Surgery in Reduction of Acid-Reducing Medication. J Surg Res. 2025 Jul; 311:112-117.

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Desai M, Ruan W, Thosani NC, Amaris M, Scott JS, Saeed A, Abu Dayyeh B, Canto MI, Abidi W, Alipour O, Amateau SK, Cosgrove N, Elhanafi SE, Forbes N, Kohli DR, Kwon RS, Fujii-Lau LL, Machicado JD, Marya NB, Ngamruengphong S, Pawa S, Sheth SG, Thiruvengadam NR, Qumseya BJ. American Society for Gastrointestinal Endoscopy guideline on the diagnosis and management of GERD: summary and recommendations. Gastrointest Endosc. 2025 Feb; 101(2):267-284.

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Dinesh D, Lee JS, Scott TM, Tucker KL, Palacios N. Proton Pump Inhibitor Use and Cognitive Function in the Boston Puerto Rican Health Study. J Gerontol A Biol Sci Med Sci. 2023 08 02; 78(8):1461-1470.

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Dinesh D, Lee JS, Scott TM, Tucker KL, Palacios N. Association between Acid-Lowering Agents, Metformin, and Vitamin B12 among Boston-Area Puerto Ricans. J Nutr. 2023 08; 153(8):2380-2388.

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Yadlapati R, Gawron AJ, Gyawali CP, Chen J, Clarke J, Fass R, Jain A, Lynch K, Khan A, Katz PO, Katzka DA, Richter J, Schnoll-Sussman F, Spechler SJ, Vaezi MF, Vela M, Pandolfino JE. Clinical role of ambulatory reflux monitoring in PPI non-responders: recommendation statements. Aliment Pharmacol Ther. 2022 10; 56(8):1274-1283.

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Santoni M, Molina-Cerrillo J, Myint ZW, Massari F, Buchler T, Buti S, Matrana MR, De Giorgi U, Rizzo M, Zabalza IO, Galli L, Zucali PA, Aurilio G, Incorvaia L, Bassanelli M, Mammone G, Salfi A, Isella L, Mollica V, Grande E, Porta C, Battelli N. Concomitant Use of Statins, Metformin, or Proton Pump Inhibitors in Patients with Advanced Renal Cell Carcinoma Treated with First-Line Combination Therapies. Target Oncol. 2022 09; 17(5):571-581.

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Linsky AM, Kressin NR, Stolzmann K, Pendergast J, Rosen AK, Bokhour BG, Simon SR. Direct-to-consumer strategies to promote deprescribing in primary care: a pilot study. BMC Prim Care. 2022 03 22; 23(1):53.

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Sayej WN. Are We Making Progress in the Hunt for Biomarkers that Could Differentiate Proton Pump Inhibitor-Responsive Eosinophilic Esophagitis? J Pediatr Gastroenterol Nutr. 2022 02 01; 74(2):173-174.

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Mollica V, Santoni M, Matrana MR, Basso U, De Giorgi U, Rizzo A, Maruzzo M, Marchetti A, Rosellini M, Bleve S, Maslov D, Tawagi K, Philon E, Blake Z, Massari F. Concomitant Proton Pump Inhibitors and Outcome of Patients Treated with Nivolumab Alone or Plus Ipilimumab for Advanced Renal Cell Carcinoma. Target Oncol. 2022 01; 17(1):61-68.

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Liu JJ, Sloan ME, Owings AH, Figgins E, Gauthier J, Gharaibeh R, Robinson T, Williams H, Sindel CB, Backus F, Ayyalasomayajula K, Parker A, Senitko M, Abraham GE, Claggett B, Horwitz BH, Jobin C, Adelman RM, Diamond G, Glover SC. Increased ACE2 Levels and Mortality Risk of Patients With COVID-19 on Proton Pump Inhibitor Therapy. Am J Gastroenterol. 2021 08 01; 116(8):1638-1645.

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