"Topoisomerase Inhibitors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Compounds that inhibit the activity of DNA TOPOISOMERASES.
| Descriptor ID |
D059003
|
| MeSH Number(s) |
D27.505.519.389.892 D27.505.954.248.794
|
| Concept/Terms |
Topoisomerase Inhibitors- Topoisomerase Inhibitors
- Inhibitors, Topoisomerase
- DNA Topoisomerase Inhibitors
- Inhibitors, DNA Topoisomerase
- Topoisomerase Inhibitors, DNA
|
Below are MeSH descriptors whose meaning is more general than "Topoisomerase Inhibitors".
Below are MeSH descriptors whose meaning is more specific than "Topoisomerase Inhibitors".
This graph shows the total number of publications written about "Topoisomerase Inhibitors" by people in this website by year, and whether "Topoisomerase Inhibitors" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 0 | 1 | 1 |
| 2015 | 1 | 0 | 1 |
| 2019 | 0 | 1 | 1 |
| 2020 | 0 | 1 | 1 |
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click here.
Below are the most recent publications written about "Topoisomerase Inhibitors" by people in Profiles.
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Barasa L, Vemana HP, Surubhotla N, Ha SS, Kong J, Yong A, Croft JL, Dukhande VV, Yoganathan S. Synthesis and Biological Evaluation of Structurally Diverse Benzimidazole Scaffolds as Potential Chemotherapeutic Agents. Anticancer Agents Med Chem. 2020; 20(3):301-314.
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Cristillo AD, Bristow CC, Torrone E, Dillon JA, Kirkcaldy RD, Dong H, Grad YH, Nicholas RA, Rice PA, Lawrence K, Oldach D, Shafer WM, Zhou P, Wi TE, Morris SR, Klausner JD. Antimicrobial Resistance in Neisseria gonorrhoeae: Proceedings of the STAR Sexually Transmitted Infection-Clinical Trial Group Programmatic Meeting. Sex Transm Dis. 2019 03; 46(3):e18-e25.
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Zhao W, Jiang G, Bi C, Li Y, Liu J, Ye C, He H, Li L, Song D, Shao R. The dual topoisomerase inhibitor A35 preferentially and specially targets topoisomerase 2a by enhancing pre-strand and post-strand cleavage and inhibiting DNA religation. Oncotarget. 2015 Nov 10; 6(35):37871-94.
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Takada S, Kelkar A, Theurkauf WE. Drosophila checkpoint kinase 2 couples centrosome function and spindle assembly to genomic integrity. Cell. 2003 Apr 04; 113(1):87-99.