Nicotinamide Phosphoribosyltransferase
"Nicotinamide Phosphoribosyltransferase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An enzyme that catalyzes the formation of nicotinamide mononucleotide (NMN) from nicotinamide and 5-phosphoribosyl-1-pyrophosphate, the rate-limiting step in the biosynthesis of the NAD coenzyme. It is also known as a growth factor for early B-LYMPHOCYTES, or an ADIPOKINE with insulin-mimetic effects (visfatin).
| Descriptor ID |
D054409
|
| MeSH Number(s) |
D08.811.913.400.725.575
|
| Concept/Terms |
Nicotinamide Phosphoribosyltransferase- Nicotinamide Phosphoribosyltransferase
- Phosphoribosyltransferase, Nicotinamide
- NAMPT Protein
- Pre-B-Cell Colony-Enhancing Factor
- Colony-Enhancing Factor, Pre-B-Cell
- Pre B Cell Colony Enhancing Factor
- Visfatin
- NAmPRTase
- NMN Pyrophosphorylase
|
Below are MeSH descriptors whose meaning is more general than "Nicotinamide Phosphoribosyltransferase".
Below are MeSH descriptors whose meaning is more specific than "Nicotinamide Phosphoribosyltransferase".
This graph shows the total number of publications written about "Nicotinamide Phosphoribosyltransferase" by people in this website by year, and whether "Nicotinamide Phosphoribosyltransferase" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2013 | 3 | 0 | 3 |
| 2023 | 1 | 0 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Nicotinamide Phosphoribosyltransferase" by people in Profiles.
-
Basse AL, Nielsen KN, Karavaeva I, Ingerslev LR, Ma T, Havelund JF, Nielsen TS, Frost M, Peics J, Dalbram E, Dall M, Zierath JR, Barr?s R, F?rgeman NJ, Treebak JT, Gerhart-Hines Z. NAMPT-dependent NAD+ biosynthesis controls circadian metabolism in a tissue-specific manner. Proc Natl Acad Sci U S A. 2023 04 04; 120(14):e2220102120.
-
Zhao B, Zhang M, Han X, Zhang XY, Xing Q, Dong X, Shi QJ, Huang P, Lu YB, Wei EQ, Xia Q, Zhang WP, Tang C. Cerebral ischemia is exacerbated by extracellular nicotinamide phosphoribosyltransferase via a non-enzymatic mechanism. PLoS One. 2013; 8(12):e85403.
-
Brandauer J, Vienberg SG, Andersen MA, Ringholm S, Risis S, Larsen PS, Kristensen JM, Fr?sig C, Leick L, Fentz J, J?rgensen S, Kiens B, Wojtaszewski JF, Richter EA, Zierath JR, Goodyear LJ, Pilegaard H, Treebak JT. AMP-activated protein kinase regulates nicotinamide phosphoribosyl transferase expression in skeletal muscle. J Physiol. 2013 Oct 15; 591(20):5207-20.
-
Venkateshaiah SU, Khan S, Ling W, Bam R, Li X, van Rhee F, Usmani S, Barlogie B, Epstein J, Yaccoby S. NAMPT/PBEF1 enzymatic activity is indispensable for myeloma cell growth and osteoclast activity. Exp Hematol. 2013 Jun; 41(6):547-557.e2.
-
Ingelsson E, Larson MG, Fox CS, Yin X, Wang TJ, Lipinska I, Pou KM, Hoffmann U, Benjamin EJ, Keaney JF, Vasan RS. Clinical correlates of circulating visfatin levels in a community-based sample. Diabetes Care. 2007 May; 30(5):1278-80.