Nicotinamide Phosphoribosyltransferase

"Nicotinamide Phosphoribosyltransferase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

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An enzyme that catalyzes the formation of nicotinamide mononucleotide (NMN) from nicotinamide and 5-phosphoribosyl-1-pyrophosphate, the rate-limiting step in the biosynthesis of the NAD coenzyme. It is also known as a growth factor for early B-LYMPHOCYTES, or an ADIPOKINE with insulin-mimetic effects (visfatin).

Descriptor ID	D054409
MeSH Number(s)	D08.811.913.400.725.575
Concept/Terms	Nicotinamide Phosphoribosyltransferase Nicotinamide Phosphoribosyltransferase Phosphoribosyltransferase, Nicotinamide NAMPT Protein Pre-B-Cell Colony-Enhancing Factor Colony-Enhancing Factor, Pre-B-Cell Pre B Cell Colony Enhancing Factor Visfatin NAmPRTase NMN Pyrophosphorylase

Below are MeSH descriptors whose meaning is more general than "Nicotinamide Phosphoribosyltransferase".

Chemicals and Drugs [D]
Enzymes and Coenzymes [D08]
Enzymes [D08.811]
Transferases [D08.811.913]
Glycosyltransferases [D08.811.913.400]
Pentosyltransferases [D08.811.913.400.725]
Nicotinamide Phosphoribosyltransferase [D08.811.913.400.725.575]

Below are MeSH descriptors whose meaning is related to "Nicotinamide Phosphoribosyltransferase".

Below are MeSH descriptors whose meaning is more specific than "Nicotinamide Phosphoribosyltransferase".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Nicotinamide Phosphoribosyltransferase" by people in this website by year, and whether "Nicotinamide Phosphoribosyltransferase" was a major or minor topic of these publications.

Bar chart showing 5 publications over 3 distinct years, with a maximum of 3 publications in 2013

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2013	3	0	3
2023	1	0	1
2025	0	1	1

Below are the most recent publications written about "Nicotinamide Phosphoribosyltransferase" by people in Profiles.

Chubanava S, Karavaeva I, Ehrlich AM, Justicia RM, Basse AL, Kulik I, Dalbram E, Ahwazi D, Heaselgrave SR, Tro?t K, Stocks B, Hodek O, Rodrigues RN, Havelund JF, Schlabs FL, Larsen S, Yonamine CY, Henriquez-Olgu?n C, Giustarini D, Rossi R, Gerhart-Hines Z, Moritz T, Zierath JR, Sakamoto K, Jensen TE, F?rgeman NJ, Lavery GG, Deshmukh AS, Treebak JT. NAD depletion in skeletal muscle does not compromise muscle function or accelerate aging. Cell Metab. 2025 Jul 01; 37(7):1460-1481.e17.

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Basse AL, Nielsen KN, Karavaeva I, Ingerslev LR, Ma T, Havelund JF, Nielsen TS, Frost M, Peics J, Dalbram E, Dall M, Zierath JR, Barr?s R, F?rgeman NJ, Treebak JT, Gerhart-Hines Z. NAMPT-dependent NAD+ biosynthesis controls circadian metabolism in a tissue-specific manner. Proc Natl Acad Sci U S A. 2023 04 04; 120(14):e2220102120.

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Zhao B, Zhang M, Han X, Zhang XY, Xing Q, Dong X, Shi QJ, Huang P, Lu YB, Wei EQ, Xia Q, Zhang WP, Tang C. Cerebral ischemia is exacerbated by extracellular nicotinamide phosphoribosyltransferase via a non-enzymatic mechanism. PLoS One. 2013; 8(12):e85403.

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Brandauer J, Vienberg SG, Andersen MA, Ringholm S, Risis S, Larsen PS, Kristensen JM, Fr?sig C, Leick L, Fentz J, J?rgensen S, Kiens B, Wojtaszewski JF, Richter EA, Zierath JR, Goodyear LJ, Pilegaard H, Treebak JT. AMP-activated protein kinase regulates nicotinamide phosphoribosyl transferase expression in skeletal muscle. J Physiol. 2013 Oct 15; 591(20):5207-20.

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Venkateshaiah SU, Khan S, Ling W, Bam R, Li X, van Rhee F, Usmani S, Barlogie B, Epstein J, Yaccoby S. NAMPT/PBEF1 enzymatic activity is indispensable for myeloma cell growth and osteoclast activity. Exp Hematol. 2013 Jun; 41(6):547-557.e2.

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Ingelsson E, Larson MG, Fox CS, Yin X, Wang TJ, Lipinska I, Pou KM, Hoffmann U, Benjamin EJ, Keaney JF, Vasan RS. Clinical correlates of circulating visfatin levels in a community-based sample. Diabetes Care. 2007 May; 30(5):1278-80.

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